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Q8AYP7

- Q8AYP7_CHICK

UniProt

Q8AYP7 - Q8AYP7_CHICK

Protein
Submitted name:

Hexokinase2

Gene

HK2

Organism
Gallus gallus (Chicken)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. hexokinase activity Source: InterPro

    GO - Biological processi

    1. carbohydrate metabolic process Source: Reactome
    2. glucose transport Source: Reactome
    3. glycolytic process Source: UniProtKB-KW
    4. small molecule metabolic process Source: Reactome

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Biological processi

    GlycolysisUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    ReactomeiREACT_115616. Glucose transport.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Hexokinase2Imported
    Gene namesi
    Name:HK2Imported
    OrganismiGallus gallus (Chicken)Imported
    Taxonomic identifieri9031 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus

    Subcellular locationi

    GO - Cellular componenti

    1. cytosol Source: Reactome

    PTM / Processingi

    Proteomic databases

    PaxDbiQ8AYP7.
    PRIDEiQ8AYP7.

    Interactioni

    Protein-protein interaction databases

    STRINGi9031.ENSGALP00000035324.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8AYP7.
    SMRiQ8AYP7. Positions 17-913.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the hexokinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG5026.
    HOGENOMiHOG000162671.
    HOVERGENiHBG005020.
    KOiK00844.
    PhylomeDBiQ8AYP7.

    Family and domain databases

    InterProiIPR001312. Hexokinase.
    IPR022673. Hexokinase_C.
    IPR019807. Hexokinase_CS.
    IPR022672. Hexokinase_N.
    [Graphical view]
    PANTHERiPTHR19443. PTHR19443. 1 hit.
    PfamiPF00349. Hexokinase_1. 2 hits.
    PF03727. Hexokinase_2. 2 hits.
    [Graphical view]
    PRINTSiPR00475. HEXOKINASE.
    PROSITEiPS00378. HEXOKINASES. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8AYP7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIASHLLAYF FTELNHDQAQ KVDKYLYHMR LSEDTLQEVS ERFRKEMEKG    50
    LGADTNPTAS VKMLPSFVRS TPDGTEDGDF LALDLGGTNF RVLRVKVSDN 100
    GLQKVEMESQ IYEIHEDLMR GSGMQLFDHI AECLGNFMEK LKIKDKKLPL 150
    GFTFSFPCHQ TKLDESILVN WTKGFKCSSV EGKDVVSLLR RAIKKRGDFD 200
    IDIVAVVNDT VGTMMSCGYD DQNCEVGLIV GTGTNACYME EMRHIDLVEG 250
    DEGRMCINME WGAFGDDGAL NDIRTEFDHE IDMGSLNPGK QLFEKMISGM 300
    YMGELVRLIL VKMAKEGLLF QGKLSSDLRT TGHFETRFVS AIEKEKEGLQ 350
    KAHEILTKLG LEPSHEDCLA THRICQIVST RSANLCGATL AARLRRIKEY 400
    KGVDPLRSTV GVDGSVYKKY PHFARRLHKT VRKLLPDCEI RFVRSEDGSG 450
    KGAAMVTAVA YRLAAQHKAR QKILEALKLS HEQLLEVKRR MRVEMEKGLG 500
    KETHAEATVK MLPTYVCSTP DGTEKGDFLA LDLGGTNFRV LLVRVRNGMR 550
    RGVEMHNKIY SIPLEVMQGT GEELFDHIVH CISDFLEYMG MKGVSLPLGF 600
    TFSFPCKQTN LDEGILLKWT KGFKATGCEG EDVVSLLKEA IHRREEFDLD 650
    VVAVVNDTVG TMMTCGYEDP YCEVGLIVGT GSNACYMEEM RNVELVEGDE 700
    GRMCVNMEWG AFGDNGCLDD IQTEFDLAVD ELSLNPGKQR FEKMISGMYL 750
    GEIVRNILMD FTKRGLLFRG RISERLKTRG IFETKFLSQI ESDCLALLQV 800
    RSILQHLGLE STCDDSIIVK EVCTVVARRA AQLCGAGMAA VVDKIRENRG 850
    LDFLKVTVGV DGTLYKLHPH FSAIMQDTVR QLSPCCEVTF LQSEDGSGKG 900
    AALITAVACR IREAGQ 916
    Length:916
    Mass (Da):102,417
    Last modified:March 1, 2003 - v1
    Checksum:i81E4A1E7D76FF550
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB083370 mRNA. Translation: BAC20933.1.
    RefSeqiNP_989543.1. NM_204212.1.
    UniGeneiGga.1055.

    Genome annotation databases

    GeneIDi374044.
    KEGGigga:374044.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB083370 mRNA. Translation: BAC20933.1 .
    RefSeqi NP_989543.1. NM_204212.1.
    UniGenei Gga.1055.

    3D structure databases

    ProteinModelPortali Q8AYP7.
    SMRi Q8AYP7. Positions 17-913.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9031.ENSGALP00000035324.

    Proteomic databases

    PaxDbi Q8AYP7.
    PRIDEi Q8AYP7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 374044.
    KEGGi gga:374044.

    Organism-specific databases

    CTDi 3099.

    Phylogenomic databases

    eggNOGi COG5026.
    HOGENOMi HOG000162671.
    HOVERGENi HBG005020.
    KOi K00844.
    PhylomeDBi Q8AYP7.

    Enzyme and pathway databases

    Reactomei REACT_115616. Glucose transport.

    Miscellaneous databases

    NextBioi 20813567.

    Family and domain databases

    InterProi IPR001312. Hexokinase.
    IPR022673. Hexokinase_C.
    IPR019807. Hexokinase_CS.
    IPR022672. Hexokinase_N.
    [Graphical view ]
    PANTHERi PTHR19443. PTHR19443. 1 hit.
    Pfami PF00349. Hexokinase_1. 2 hits.
    PF03727. Hexokinase_2. 2 hits.
    [Graphical view ]
    PRINTSi PR00475. HEXOKINASE.
    PROSITEi PS00378. HEXOKINASES. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and gene expression of hexokinase I and II in the chicken skeletal muscle."
      Seki Y., Sato K., Kono T., Akiba Y.
      Anim. Sci. J. 76:491-497(2005)
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ8AYP7_CHICK
    AccessioniPrimary (citable) accession number: Q8AYP7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)