Q8AYP7 (Q8AYP7_CHICK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hexokinase2 EMBL BAC20933.1

Gene names

Name:

HK2 EMBL BAC20933.1

Organism

Gallus gallus (Chicken) EMBL BAC20933.1

Taxonomic identifier

9031 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Sauropsida › Sauria › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Phasianinae › Gallus

Protein attributes

Sequence length	916 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the hexokinase family. RuleBase RU004510

Ontologies

Keywords
Biological process	Glycolysis RuleBase RU004049 SAAS SAAS001312
Ligand	ATP-binding RuleBase RU004049 SAAS SAAS001312 Nucleotide-binding
Molecular function	Kinase SAAS SAAS001312 RuleBase RU004049 EMBL BAC20933.1 Transferase
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Traceable author statement. Source: Reactome glucose transport Traceable author statement. Source: Reactome glycolysis Inferred from electronic annotation. Source: UniProtKB-KW small molecule metabolic process Traceable author statement. Source: Reactome
Cellular_component	cytosol Traceable author statement. Source: Reactome
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW hexokinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8AYP7 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 81E4A1E7D76FF550	FASTA	916	102,417
	10 20 30 40 50 60 MIASHLLAYF FTELNHDQAQ KVDKYLYHMR LSEDTLQEVS ERFRKEMEKG LGADTNPTAS 70 80 90 100 110 120 VKMLPSFVRS TPDGTEDGDF LALDLGGTNF RVLRVKVSDN GLQKVEMESQ IYEIHEDLMR 130 140 150 160 170 180 GSGMQLFDHI AECLGNFMEK LKIKDKKLPL GFTFSFPCHQ TKLDESILVN WTKGFKCSSV 190 200 210 220 230 240 EGKDVVSLLR RAIKKRGDFD IDIVAVVNDT VGTMMSCGYD DQNCEVGLIV GTGTNACYME 250 260 270 280 290 300 EMRHIDLVEG DEGRMCINME WGAFGDDGAL NDIRTEFDHE IDMGSLNPGK QLFEKMISGM 310 320 330 340 350 360 YMGELVRLIL VKMAKEGLLF QGKLSSDLRT TGHFETRFVS AIEKEKEGLQ KAHEILTKLG 370 380 390 400 410 420 LEPSHEDCLA THRICQIVST RSANLCGATL AARLRRIKEY KGVDPLRSTV GVDGSVYKKY 430 440 450 460 470 480 PHFARRLHKT VRKLLPDCEI RFVRSEDGSG KGAAMVTAVA YRLAAQHKAR QKILEALKLS 490 500 510 520 530 540 HEQLLEVKRR MRVEMEKGLG KETHAEATVK MLPTYVCSTP DGTEKGDFLA LDLGGTNFRV 550 560 570 580 590 600 LLVRVRNGMR RGVEMHNKIY SIPLEVMQGT GEELFDHIVH CISDFLEYMG MKGVSLPLGF 610 620 630 640 650 660 TFSFPCKQTN LDEGILLKWT KGFKATGCEG EDVVSLLKEA IHRREEFDLD VVAVVNDTVG 670 680 690 700 710 720 TMMTCGYEDP YCEVGLIVGT GSNACYMEEM RNVELVEGDE GRMCVNMEWG AFGDNGCLDD 730 740 750 760 770 780 IQTEFDLAVD ELSLNPGKQR FEKMISGMYL GEIVRNILMD FTKRGLLFRG RISERLKTRG 790 800 810 820 830 840 IFETKFLSQI ESDCLALLQV RSILQHLGLE STCDDSIIVK EVCTVVARRA AQLCGAGMAA 850 860 870 880 890 900 VVDKIRENRG LDFLKVTVGV DGTLYKLHPH FSAIMQDTVR QLSPCCEVTF LQSEDGSGKG 910 AALITAVACR IREAGQ

References

[1]	"Cloning and gene expression of hexokinase I and II in the chicken skeletal muscle." Seki Y., Sato K., Kono T., Akiba Y. Anim. Sci. J. 76:491-497(2005) Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB083370 mRNA. Translation: BAC20933.1.
IPI	IPI00582456.
RefSeq	NP_989543.1. NM_204212.1.
UniGene	Gga.1055.
3D structure databases
ProteinModelPortal	Q8AYP7.
SMR	Q8AYP7. Positions 17-913.
ModBase	Search...
Protein-protein interaction databases
STRING	9031.ENSGALP00000035324.
Proteomic databases
PaxDb	Q8AYP7.
PRIDE	Q8AYP7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	374044.
KEGG	gga:374044.
Organism-specific databases
CTD	3099.
Phylogenomic databases
eggNOG	COG5026.
HOGENOM	HOG000162671.
HOVERGEN	HBG005020.
KO	K00844.
Enzyme and pathway databases
Reactome	REACT_115655. Metabolism.
Family and domain databases
InterPro	IPR001312. Hexokinase. IPR022673. Hexokinase_C. IPR019807. Hexokinase_CS. IPR022672. Hexokinase_N. [Graphical view]
PANTHER	PTHR19443. PTHR19443. 1 hit.
Pfam	PF00349. Hexokinase_1. 2 hits. PF03727. Hexokinase_2. 2 hits. [Graphical view]
PRINTS	PR00475. HEXOKINASE.
PROSITE	PS00378. HEXOKINASES. 2 hits. [Graphical view]
ProtoNet	Search...
Other
NextBio	20813567.

Entry information

Entry name

Q8AYP7_CHICK

Accession

Primary (citable) accession number: Q8AYP7

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	May 29, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)