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Protein
Submitted name:

Hexokinase2

Gene

HK2

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseSAAS annotationImported, Transferase
Biological processGlycolysisSAAS annotation
LigandATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-GGA-352832. Glucose transport.

Names & Taxonomyi

Protein namesi
Submitted name:
Hexokinase2Imported
Gene namesi
Name:HK2Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Structurei

3D structure databases

ProteinModelPortaliQ8AYP7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini22 – 219Hexokinase_1InterPro annotationAdd BLAST198
Domaini225 – 459Hexokinase_2InterPro annotationAdd BLAST235
Domaini471 – 667Hexokinase_1InterPro annotationAdd BLAST197
Domaini673 – 907Hexokinase_2InterPro annotationAdd BLAST235

Sequence similaritiesi

Belongs to the hexokinase family.SAAS annotation

Phylogenomic databases

HOGENOMiHOG000162671.
HOVERGENiHBG005020.
PhylomeDBiQ8AYP7.

Family and domain databases

InterProiView protein in InterPro
IPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
PANTHERiPTHR19443. PTHR19443. 4 hits.
PfamiView protein in Pfam
PF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
PROSITEiView protein in PROSITE
PS00378. HEXOKINASE_1. 2 hits.
PS51748. HEXOKINASE_2. 2 hits.

Sequencei

Sequence statusi: Complete.

Q8AYP7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIASHLLAYF FTELNHDQAQ KVDKYLYHMR LSEDTLQEVS ERFRKEMEKG
60 70 80 90 100
LGADTNPTAS VKMLPSFVRS TPDGTEDGDF LALDLGGTNF RVLRVKVSDN
110 120 130 140 150
GLQKVEMESQ IYEIHEDLMR GSGMQLFDHI AECLGNFMEK LKIKDKKLPL
160 170 180 190 200
GFTFSFPCHQ TKLDESILVN WTKGFKCSSV EGKDVVSLLR RAIKKRGDFD
210 220 230 240 250
IDIVAVVNDT VGTMMSCGYD DQNCEVGLIV GTGTNACYME EMRHIDLVEG
260 270 280 290 300
DEGRMCINME WGAFGDDGAL NDIRTEFDHE IDMGSLNPGK QLFEKMISGM
310 320 330 340 350
YMGELVRLIL VKMAKEGLLF QGKLSSDLRT TGHFETRFVS AIEKEKEGLQ
360 370 380 390 400
KAHEILTKLG LEPSHEDCLA THRICQIVST RSANLCGATL AARLRRIKEY
410 420 430 440 450
KGVDPLRSTV GVDGSVYKKY PHFARRLHKT VRKLLPDCEI RFVRSEDGSG
460 470 480 490 500
KGAAMVTAVA YRLAAQHKAR QKILEALKLS HEQLLEVKRR MRVEMEKGLG
510 520 530 540 550
KETHAEATVK MLPTYVCSTP DGTEKGDFLA LDLGGTNFRV LLVRVRNGMR
560 570 580 590 600
RGVEMHNKIY SIPLEVMQGT GEELFDHIVH CISDFLEYMG MKGVSLPLGF
610 620 630 640 650
TFSFPCKQTN LDEGILLKWT KGFKATGCEG EDVVSLLKEA IHRREEFDLD
660 670 680 690 700
VVAVVNDTVG TMMTCGYEDP YCEVGLIVGT GSNACYMEEM RNVELVEGDE
710 720 730 740 750
GRMCVNMEWG AFGDNGCLDD IQTEFDLAVD ELSLNPGKQR FEKMISGMYL
760 770 780 790 800
GEIVRNILMD FTKRGLLFRG RISERLKTRG IFETKFLSQI ESDCLALLQV
810 820 830 840 850
RSILQHLGLE STCDDSIIVK EVCTVVARRA AQLCGAGMAA VVDKIRENRG
860 870 880 890 900
LDFLKVTVGV DGTLYKLHPH FSAIMQDTVR QLSPCCEVTF LQSEDGSGKG
910
AALITAVACR IREAGQ
Length:916
Mass (Da):102,417
Last modified:March 1, 2003 - v1
Checksum:i81E4A1E7D76FF550
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB083370 mRNA. Translation: BAC20933.1.
RefSeqiNP_989543.1. NM_204212.1.
UniGeneiGga.1055.

Genome annotation databases

GeneIDi374044.

Similar proteinsi

Entry informationi

Entry nameiQ8AYP7_CHICK
AccessioniPrimary (citable) accession number: Q8AYP7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: October 25, 2017
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)