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Q8AYP7

- Q8AYP7_CHICK

UniProt

Q8AYP7 - Q8AYP7_CHICK

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Protein
Submitted name: Hexokinase2
Gene
HK2
Organism
Gallus gallus (Chicken)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. hexokinase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. carbohydrate metabolic process Source: Reactome
  2. glucose transport Source: Reactome
  3. glycolytic process Source: UniProtKB-KW
  4. small molecule metabolic process Source: Reactome
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

ReactomeiREACT_115616. Glucose transport.

Names & Taxonomyi

Protein namesi
Submitted name:
Hexokinase2Imported
Gene namesi
Name:HK2Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: Reactome
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ8AYP7.
PRIDEiQ8AYP7.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000035324.

Structurei

3D structure databases

ProteinModelPortaliQ8AYP7.
SMRiQ8AYP7. Positions 17-913.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG5026.
HOGENOMiHOG000162671.
HOVERGENiHBG005020.
KOiK00844.
PhylomeDBiQ8AYP7.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8AYP7-1 [UniParc]FASTAAdd to Basket

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MIASHLLAYF FTELNHDQAQ KVDKYLYHMR LSEDTLQEVS ERFRKEMEKG    50
LGADTNPTAS VKMLPSFVRS TPDGTEDGDF LALDLGGTNF RVLRVKVSDN 100
GLQKVEMESQ IYEIHEDLMR GSGMQLFDHI AECLGNFMEK LKIKDKKLPL 150
GFTFSFPCHQ TKLDESILVN WTKGFKCSSV EGKDVVSLLR RAIKKRGDFD 200
IDIVAVVNDT VGTMMSCGYD DQNCEVGLIV GTGTNACYME EMRHIDLVEG 250
DEGRMCINME WGAFGDDGAL NDIRTEFDHE IDMGSLNPGK QLFEKMISGM 300
YMGELVRLIL VKMAKEGLLF QGKLSSDLRT TGHFETRFVS AIEKEKEGLQ 350
KAHEILTKLG LEPSHEDCLA THRICQIVST RSANLCGATL AARLRRIKEY 400
KGVDPLRSTV GVDGSVYKKY PHFARRLHKT VRKLLPDCEI RFVRSEDGSG 450
KGAAMVTAVA YRLAAQHKAR QKILEALKLS HEQLLEVKRR MRVEMEKGLG 500
KETHAEATVK MLPTYVCSTP DGTEKGDFLA LDLGGTNFRV LLVRVRNGMR 550
RGVEMHNKIY SIPLEVMQGT GEELFDHIVH CISDFLEYMG MKGVSLPLGF 600
TFSFPCKQTN LDEGILLKWT KGFKATGCEG EDVVSLLKEA IHRREEFDLD 650
VVAVVNDTVG TMMTCGYEDP YCEVGLIVGT GSNACYMEEM RNVELVEGDE 700
GRMCVNMEWG AFGDNGCLDD IQTEFDLAVD ELSLNPGKQR FEKMISGMYL 750
GEIVRNILMD FTKRGLLFRG RISERLKTRG IFETKFLSQI ESDCLALLQV 800
RSILQHLGLE STCDDSIIVK EVCTVVARRA AQLCGAGMAA VVDKIRENRG 850
LDFLKVTVGV DGTLYKLHPH FSAIMQDTVR QLSPCCEVTF LQSEDGSGKG 900
AALITAVACR IREAGQ 916
Length:916
Mass (Da):102,417
Last modified:March 1, 2003 - v1
Checksum:i81E4A1E7D76FF550
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB083370 mRNA. Translation: BAC20933.1.
RefSeqiNP_989543.1. NM_204212.1.
UniGeneiGga.1055.

Genome annotation databases

GeneIDi374044.
KEGGigga:374044.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB083370 mRNA. Translation: BAC20933.1 .
RefSeqi NP_989543.1. NM_204212.1.
UniGenei Gga.1055.

3D structure databases

ProteinModelPortali Q8AYP7.
SMRi Q8AYP7. Positions 17-913.
ModBasei Search...

Protein-protein interaction databases

STRINGi 9031.ENSGALP00000035324.

Proteomic databases

PaxDbi Q8AYP7.
PRIDEi Q8AYP7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 374044.
KEGGi gga:374044.

Organism-specific databases

CTDi 3099.

Phylogenomic databases

eggNOGi COG5026.
HOGENOMi HOG000162671.
HOVERGENi HBG005020.
KOi K00844.
PhylomeDBi Q8AYP7.

Enzyme and pathway databases

Reactomei REACT_115616. Glucose transport.

Miscellaneous databases

NextBioi 20813567.

Family and domain databases

InterProi IPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view ]
PANTHERi PTHR19443. PTHR19443. 1 hit.
Pfami PF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view ]
PRINTSi PR00475. HEXOKINASE.
PROSITEi PS00378. HEXOKINASES. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cloning and gene expression of hexokinase I and II in the chicken skeletal muscle."
    Seki Y., Sato K., Kono T., Akiba Y.
    Anim. Sci. J. 76:491-497(2005)
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ8AYP7_CHICK
AccessioniPrimary (citable) accession number: Q8AYP7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: September 3, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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