Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Hemoglobin beta chain

Gene
N/A
Organism
Thunnus thynnus (Atlantic bluefin tuna) (Scomber thynnus)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi93 – 931Iron (heme axial ligand); via tele nitrogenCombined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Oxygen transportUniRule annotationSAAS annotation, Transport

Keywords - Ligandi

HemeUniRule annotationCombined sourcesSAAS annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Hemoglobin beta chainImported
OrganismiThunnus thynnus (Atlantic bluefin tuna) (Scomber thynnus)Imported
Taxonomic identifieri8237 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataPelagiariaScombriformesScombridaeThunnus

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1V4UX-ray2.00B/D2-147[»]
1V4WX-ray1.70B/D2-147[»]
1V4XX-ray1.60B/D2-147[»]
ProteinModelPortaliQ8AYM1.
SMRiQ8AYM1. Positions 2-147.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8AYM1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 147143GLOBINInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the globin family.UniRule annotationSAAS annotation

Phylogenomic databases

HOVERGENiHBG009709.

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin/Proto.
IPR002337. Haemoglobin_b.
[Graphical view]
PfamiPF00042. Globin. 1 hit.
[Graphical view]
PRINTSiPR00814. BETAHAEM.
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8AYM1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVEWTQQERS IIAGIFANLN YEDIGPKALA RCLIVYPWTQ RYFGAYGDLS
60 70 80 90 100
TPDAIKGNAK IAAHGVKVLH GLDRAVKNMD NINEAYSELS VLHSDKLHVD
110 120 130 140
PDNFRILGDC LTVVIAANLG DAFTVETQCA FQKFLAVVVF ALGRKYH
Length:147
Mass (Da):16,313
Last modified:March 1, 2003 - v1
Checksum:iD22C5A98EC4A2F4A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB093568 mRNA. Translation: BAC21255.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB093568 mRNA. Translation: BAC21255.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1V4UX-ray2.00B/D2-147[»]
1V4WX-ray1.70B/D2-147[»]
1V4XX-ray1.60B/D2-147[»]
ProteinModelPortaliQ8AYM1.
SMRiQ8AYM1. Positions 2-147.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG009709.

Miscellaneous databases

EvolutionaryTraceiQ8AYM1.

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin/Proto.
IPR002337. Haemoglobin_b.
[Graphical view]
PfamiPF00042. Globin. 1 hit.
[Graphical view]
PRINTSiPR00814. BETAHAEM.
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Novel mechanisms of pH sensitivity in tuna hemoglobin: a structural explanation of the root effect."
    Yokoyama T., Chong K.T., Miyazaki G., Morimoto H., Shih D.T., Unzai S., Tame J.R., Park S.Y.
    J. Biol. Chem. 279:28632-28640(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ8AYM1_THUTH
AccessioniPrimary (citable) accession number: Q8AYM1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: May 11, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.