Unreviewed, UniProtKB/TrEMBL Q8AYM1 (Q8AYM1_THUTH)

Names and origin

Protein names	Submitted name:     Hemoglobin beta chain EMBL BAC21255.1
Organism	Thunnus thynnus (Bluefin tuna) EMBL BAC21255.1
Taxonomic identifier	8237 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Euteleostei › Neoteleostei › Acanthomorpha › Acanthopterygii › Percomorpha › Perciformes › Scombroidei › Scombridae › Thunnus

Protein attributes

Sequence length	147 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Belongs to the globin family. RuleBase RU000356V1

Ontologies

Keywords
Biological process	Oxygen transport Spearmint SPM002337 RuleBase RU000356V1 Transport
Ligand	Heme Spearmint SPM002337 RuleBase RU000356V1 Iron Metal-binding
Gene Ontology (GO)
Biological process	oxygen transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	hemoglobin complex Inferred from electronic annotation. Source: InterPro
Molecular function	heme binding Inferred from electronic annotation. Source: InterPro oxygen binding Inferred from electronic annotation. Source: InterPro oxygen transporter activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8AYM1-1 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: D22C5A98EC4A2F4A	FASTA	147	16,313
	10 20 30 40 50 60 MVEWTQQERS IIAGIFANLN YEDIGPKALA RCLIVYPWTQ RYFGAYGDLS TPDAIKGNAK 70 80 90 100 110 120 IAAHGVKVLH GLDRAVKNMD NINEAYSELS VLHSDKLHVD PDNFRILGDC LTVVIAANLG 130 140 DAFTVETQCA FQKFLAVVVF ALGRKYH

References

[1]	"Novel mechanisms of pH sensitivity in tuna hemoglobin: a structural explanation of the root effect." Yokoyama T., Chong K.T., Miyazaki G., Morimoto H., Shih D.T., Unzai S., Tame J.R., Park S.Y. J. Biol. Chem. 279:28632-28640(2004) [PubMed: 15117955] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBLGenBankDDBJ

AB093568 mRNA. Translation: BAC21255.1.

3D structure databases

PDBPDBe

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1V4U	X-ray	2.00	B/D	2-147	[»]
1V4W	X-ray	1.70	B/D	2-147	[»]
1V4X	X-ray	1.60	B/D	2-147	[»]

ModBase

Search...

Phylogenomic databases

HOVERGEN

Q8AYM1.

Family and domain databases

InterPro

IPR012292. Globin.
IPR009050. Globin-like.
IPR000971. Globin_subset.
IPR002337. Haemoglobin_b.
[Graphical view]

Gene3D

G3DSA:1.10.490.10. Globin_related. 1 hit.

PANTHER

PTHR11442:SF7. Beta_haem. 1 hit.

Pfam

PF00042. Globin. 1 hit.
[Graphical view]

PRINTS

PR00814. BETAHAEM.

PROSITE

PS01033. GLOBIN. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q8AYM1_THUTH

Accession

Primary (citable) accession number: Q8AYM1

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	November 3, 2009
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)