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Protein
Submitted name:

Hemoglobin alpha chain 1

Gene
N/A
Organism
Thunnus thynnus (Atlantic bluefin tuna) (Scomber thynnus)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi61Iron (heme distal ligand)PROSITE-ProRule annotation1
Metal bindingi90Iron (heme 1 axial ligand); via tele nitrogenCombined sources1
Metal bindingi90Iron (heme proximal ligand)PROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Biological processOxygen transportPROSITE-ProRule annotationSAAS annotation, Transport
LigandHemePROSITE-ProRule annotationCombined sourcesSAAS annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Hemoglobin alpha chain 1Imported
OrganismiThunnus thynnus (Atlantic bluefin tuna) (Scomber thynnus)Imported
Taxonomic identifieri8237 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataPelagiariaScombriformesScombridaeThunnus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1V4UX-ray2.00A/C2-144[»]
1V4WX-ray1.70A/C2-144[»]
1V4XX-ray1.60A/C2-144[»]
ProteinModelPortaliQ8AYM0
SMRiQ8AYM0
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8AYM0

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 144GLOBINInterPro annotationAdd BLAST141

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

HOVERGENiHBG009709

Family and domain databases

CDDicd08927 Hb-alpha_like, 1 hit
Gene3Di1.10.490.10, 1 hit
InterProiView protein in InterPro
IPR000971 Globin
IPR009050 Globin-like_sf
IPR012292 Globin/Proto
IPR002338 Haemoglobin_a-typ
IPR002339 Haemoglobin_pi
PfamiView protein in Pfam
PF00042 Globin, 1 hit
PRINTSiPR00612 ALPHAHAEM
PR00815 PIHAEM
SUPFAMiSSF46458 SSF46458, 1 hit
PROSITEiView protein in PROSITE
PS01033 GLOBIN, 1 hit

Sequencei

Sequence statusi: Complete.

Q8AYM0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTLSDKDKS TVKALWGKIS KSADAIGADA LGRMLAVYPQ TKTYFSHWPD
60 70 80 90 100
MSPGSGPVKA HGKKVMGGVA LAVSKIDDLT TGLGDLSELH AFKMRVDPSN
110 120 130 140
FKILSHCILV VVAKMFPKEF TPDAHVSLDK FLASVALALA ERYR
Length:144
Mass (Da):15,563
Last modified:March 1, 2003 - v1
Checksum:i5793FECA3ACB9DF6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB093569 mRNA Translation: BAC21256.1

Similar proteinsi

Entry informationi

Entry nameiQ8AYM0_THUTH
AccessioniPrimary (citable) accession number: Q8AYM0
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: April 25, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

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