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Protein
Submitted name:

Hemoglobin alpha chain 1

Gene
N/A
Organism
Thunnus thynnus (Atlantic bluefin tuna) (Scomber thynnus)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi61Iron (heme distal ligand)PROSITE-ProRule annotation1
Metal bindingi90Iron (heme 1 axial ligand); via tele nitrogenCombined sources1
Metal bindingi90Iron (heme proximal ligand)PROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Biological processOxygen transportPROSITE-ProRule annotationSAAS annotation, Transport
LigandHemePROSITE-ProRule annotationCombined sourcesSAAS annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Hemoglobin alpha chain 1Imported
OrganismiThunnus thynnus (Atlantic bluefin tuna) (Scomber thynnus)Imported
Taxonomic identifieri8237 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataPelagiariaScombriformesScombridaeThunnus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1V4UX-ray2.00A/C2-144[»]
1V4WX-ray1.70A/C2-144[»]
1V4XX-ray1.60A/C2-144[»]
ProteinModelPortaliQ8AYM0.
SMRiQ8AYM0.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8AYM0.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 144GLOBINInterPro annotationAdd BLAST141

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

HOVERGENiHBG009709.

Family and domain databases

CDDicd08927. Hb-alpha_like. 1 hit.
InterProiView protein in InterPro
IPR000971. Globin.
IPR009050. Globin-like.
IPR002338. Haemoglobin_a-typ.
IPR002339. Haemoglobin_pi.
PfamiView protein in Pfam
PF00042. Globin. 1 hit.
PRINTSiPR00612. ALPHAHAEM.
PR00815. PIHAEM.
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiView protein in PROSITE
PS01033. GLOBIN. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8AYM0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTLSDKDKS TVKALWGKIS KSADAIGADA LGRMLAVYPQ TKTYFSHWPD
60 70 80 90 100
MSPGSGPVKA HGKKVMGGVA LAVSKIDDLT TGLGDLSELH AFKMRVDPSN
110 120 130 140
FKILSHCILV VVAKMFPKEF TPDAHVSLDK FLASVALALA ERYR
Length:144
Mass (Da):15,563
Last modified:March 1, 2003 - v1
Checksum:i5793FECA3ACB9DF6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB093569 mRNA. Translation: BAC21256.1.

Similar proteinsi

Entry informationi

Entry nameiQ8AYM0_THUTH
AccessioniPrimary (citable) accession number: Q8AYM0
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: August 30, 2017
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources