Hemoglobin alpha chain 1 - Thunnus thynnus (Bluefin tuna)

Contribute

Read comments (0) or add your own

Unreviewed, UniProtKB/TrEMBL Q8AYM0 (Q8AYM0_THUTH)

Last modified November 3, 2009. Version 40. History...

Clusters with 100%, 90%, 50% identity |

Third-party data |

Customize display

text xml rdf/xml gff fasta

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information

Names and origin

Protein names	Submitted name: Hemoglobin alpha chain 1 EMBL BAC21256.1
Organism	Thunnus thynnus (Bluefin tuna) EMBL BAC21256.1
Taxonomic identifier	8237 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Euteleostei › Neoteleostei › Acanthomorpha › Acanthopterygii › Percomorpha › Perciformes › Scombroidei › Scombridae › Thunnus

Protein attributes

Sequence length	144 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level.

General annotation (Comments)

Sequence similarities

Belongs to the globin family.

Ontologies

Keywords
Biological process	Oxygen transport RuleBase RU000356V1 Spearmint SPM002338 Transport
Ligand	Heme RuleBase RU000356V1 Spearmint SPM002338 Iron Metal-binding
Gene Ontology (GO)
Biological process	oxygen transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	hemoglobin complex Inferred from electronic annotation. Source: InterPro
Molecular function	heme binding Inferred from electronic annotation. Source: InterPro oxygen binding Inferred from electronic annotation. Source: InterPro oxygen transporter activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

Q8AYM0-1 [UniParc].

Last modified March 1, 2003. Version 1.
Checksum: 5793FECA3ACB9DF6
Show »

144

15,563

        10         20         30         40         50         60 
MTTLSDKDKS TVKALWGKIS KSADAIGADA LGRMLAVYPQ TKTYFSHWPD MSPGSGPVKA 

        70         80         90        100        110        120 
HGKKVMGGVA LAVSKIDDLT TGLGDLSELH AFKMRVDPSN FKILSHCILV VVAKMFPKEF 

       130        140 
TPDAHVSLDK FLASVALALA ERYR

References

[1]	"Novel mechanisms of pH sensitivity in tuna hemoglobin: a structural explanation of the root effect." Yokoyama T., Chong K.T., Miyazaki G., Morimoto H., Shih D.T., Unzai S., Tame J.R., Park S.Y. J. Biol. Chem. 279:28632-28640(2004) [PubMed: 15117955] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AB093569 mRNA. Translation: BAC21256.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1V4U	X-ray	2.00	A/C	2-144	[»]
1V4W	X-ray	1.70	A/C	2-144	[»]
1V4X	X-ray	1.60	A/C	2-144	[»]

ModBase

Phylogenomic databases

HOVERGEN

Family and domain databases

InterPro

IPR012292. Globin.
IPR009050. Globin-like.
IPR000971. Globin_subset.
IPR002338. Haemoglobin_a.
IPR002339. Haemoglobin_pi.
[Graphical view]

Gene3D

G3DSA:1.10.490.10. Globin_related. 1 hit.

Pfam

PF00042. Globin. 1 hit.
[Graphical view]

PRINTS

PR00612. ALPHAHAEM.
PR00815. PIHAEM.

PROSITE

PS01033. GLOBIN. 1 hit.
[Graphical view]

ProtoNet

Entry information

Entry name

Q8AYM0_THUTH

Accession

Primary (citable) accession number: Q8AYM0

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	November 3, 2009
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information