Q8AYI3 (Q8AYI3_CHICK) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Aconitase EMBL AAN63562.1
EC=4.2.1.3 EMBL AAN63562.1

Gene names

Name:

ACO2 EMBL AAN63562.1

Organism

Gallus gallus (Chicken) EMBL AAN63562.1

Taxonomic identifier

9031 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Phasianinae › Gallus

Protein attributes

Sequence length	785 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	Transit peptide EMBL AAN63562.1
Molecular function	Lyase EMBL AAN63562.1
Gene Ontology (GO)
Molecular function	4 iron, 4 sulfur cluster binding Inferred from electronic annotation. Source: InterPro aconitate hydratase activity Inferred from electronic annotation. Source: EC citrate hydro-lyase (cis-aconitate-forming) activity Inferred from electronic annotation. Source: EC isocitrate hydro-lyase (cis-aconitate-forming) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 29	29	Potential EMBL AAN63562.1
	Chain	30 – 785	756	aconitase EMBL AAN63562.1		PRO_5000061703

Sequences

	Sequence		Length	Mass (Da)
	Q8AYI3 [UniParc]. Last modified March 1, 2003. Version 1. Checksum: 3EFC4E1178D12852	FASTA	785	85,791
	10 20 30 40 50 60 MAPYCVWLAR LRHALNGGIR RYHVASVLCQ RAKVAMSHFE PNEYINYEKL EKNINIVRKR 70 80 90 100 110 120 LDRPLTLSEK IVYGHLDDPA KQEIERGKTY LRLRPDRVAM QDATAQMAML QFISSGLPKV 130 140 150 160 170 180 AVPSTIHCDH LIEAQLGGEK DLRRAKDINQ EVYNFLSTAG AKYGVGFWKP GSGIIHQIIL 190 200 210 220 230 240 ENYSYPGVML IGTDSHTPNG GGLGGICIGV GGADAVDVMA GIPWELKCPK VIGVKLTGKL 250 260 270 280 290 300 SGWSSPKDVI LKVAGILTVK GGTGAIIEYH GPGVDSISCT GMATICNMGA EIGATTSVFP 310 320 330 340 350 360 YNTRMKKYLG KTGRADIAAL ADEFQQYLVP DAGCQYDQVI EINLSELKPH INGPFTPDLA 370 380 390 400 410 420 HPVSDVGAVA EKEGWPVDIR VGLIGSCTNS SYEDMGRSAA VAKQALAHGL KCKSKFTITP 430 440 450 460 470 480 GSEQIRATIE RDGYAQILRD VGGLILANAC GPCIGQWDRK DIKKGEKNTI VTSYNRNFTG 490 500 510 520 530 540 RNDANPETHA FVTSPEIVTA LSIAGTLKFN PETDFLTGAD GKKFKLEAPD ADELPRLDFD 550 560 570 580 590 600 PGQDTYQYPP KDGSGQHVDV SPTSQRLQLL EPFDKWDGKD LEDMLILIKV KGKCTTDHIS 610 620 630 640 650 660 AAGPWLKFRG HLDNISNNLL IGAINIENGK ANSVRNALTQ EFGPVPDTAR YYKKMGVKWA 670 680 690 700 710 720 VIGDENYGEG SSREHAALEP RHLGGRVIIT KSFARIHETN LKKQGLLPLT FADPADYNKI 730 740 750 760 770 780 HPVDKLSIVG LADFAPGKPL KCIIKHPNGS QETIMLNHTF NESQIEWFQA GSALNRMKEL QQKSS

References

[1]	"Linkage mapping of the mitochondrial aconitase (ACO2) gene to chicken chromosome 1." Shimogiri T., Miyagawa S., Lee E.J., Mannen H., Okamoto S., Maeda Y., Tsuji S. Anim. Genet. 33:312-312(2002) [PubMed: 12139513] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Heart EMBL AAN63562.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF428141 mRNA. Translation: AAN63562.1.
IPI	IPI00576187.
RefSeq	NP_989519.1. NM_204188.2.
UniGene	Gga.4054.
3D structure databases
HSSP	HSSP built from PDB template 7ACN based on UniProtKB P16276.
ProteinModelPortal	Q8AYI3.
SMR	Q8AYI3. Positions 31-783.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8AYI3.
Proteomic databases
PRIDE	Q8AYI3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	374009.
KEGG	gga:374009.
Organism-specific databases
CTD	50.
Phylogenomic databases
GeneTree	ENSGT00530000063060.
HOVERGEN	HBG000248.
InParanoid	Q8AYI3.
Family and domain databases
InterPro	IPR015931. Acnase/IPM_dHydase_lsu_aba_1/3. IPR015937. Acoase/IPM_deHydtase. IPR001030. Acoase/IPM_deHydtase_lsu_aba. IPR015928. Aconitase/3IPM_dehydase_swvl. IPR015932. Aconitase/IPMdHydase_lsu_aba_2. IPR018136. Aconitase_4Fe-4S_BS. IPR006248. Aconitase_mito-like. IPR000573. AconitaseA/IPMdHydase_ssu_swvl. [Graphical view]
Gene3D	G3DSA:3.30.499.10. Acnase/IPM_dHydase_lsu_aba_1/3. 2 hits. G3DSA:3.20.19.10. Aconitase/3IPM_dehydase_swvl. 1 hit. G3DSA:3.40.1060.10. Aconitase/IPMdHydase_lsu_aba_2. 1 hit.
KO	K01681.
PANTHER	PTHR11670. Aconitase-like_core. 1 hit. PTHR11670:SF5. Aconitase_mito. 1 hit.
Pfam	PF00330. Aconitase. 1 hit. PF00694. Aconitase_C. 1 hit. [Graphical view]
PRINTS	PR00415. ACONITASE.
SUPFAM	SSF52016. Aconitase/3IPM_dehydase_swvl. 1 hit. SSF53732. Aconitase_N. 1 hit.
TIGRFAMs	TIGR01340. Aconitase_mito. 1 hit.
PROSITE	PS00450. ACONITASE_1. 1 hit. PS01244. ACONITASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8AYI3_CHICK

Accession

Primary (citable) accession number: Q8AYI3

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2003
Last sequence update:	March 1, 2003
Last modified:	November 16, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)