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Q8AXI4

- Q8AXI4_GINCI

UniProt

Q8AXI4 - Q8AXI4_GINCI

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Protein
Submitted name:

Novel antigen receptor

Gene
N/A
Organism
Ginglymostoma cirratum (Nurse shark)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei12 – 121ChlorideImported
Binding sitei19 – 191Chloride; via amide nitrogenImported

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Novel antigen receptorImported
OrganismiGinglymostoma cirratum (Nurse shark)Imported
Taxonomic identifieri7801 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataChondrichthyesElasmobranchiiGaleomorphiiGaleoideaOrectolobiformesGinglymostomatidaeGinglymostoma

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1SQ2X-ray1.45N1-113[»]
1T6VX-ray1.70N/O1-113[»]
ProteinModelPortaliQ8AXI4.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8AXI4.

Family & Domainsi

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00409. IG. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8AXI4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
ARVDQTPRSV TKETGESLTI NCVLRDASYA LGSTCWYRKK SGEGNEESIS
60 70 80 90 100
KGGRYVETVN SGSKSFSLRI NDLTVEDGGT YRCGLGVAGG YCDYALCSSR
110
YAECGDGTAV TVN
Length:113
Mass (Da):12,042
Last modified:March 1, 2003 - v1
Checksum:i71522771FEA75661
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei113 – 1131Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF447096 mRNA. Translation: AAN75852.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF447096 mRNA. Translation: AAN75852.1 .

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1SQ2 X-ray 1.45 N 1-113 [» ]
1T6V X-ray 1.70 N/O 1-113 [» ]
ProteinModelPortali Q8AXI4.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

EvolutionaryTracei Q8AXI4.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
[Graphical view ]
Pfami PF07686. V-set. 1 hit.
[Graphical view ]
SMARTi SM00409. IG. 1 hit.
[Graphical view ]
PROSITEi PS50835. IG_LIKE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Selection and characterization of naturally occurring single-domain (IgNAR) antibody fragments from immunized sharks by phage display."
    Dooley H., Flajnik M.F., Porter A.J.
    Mol. Immunol. 40:25-33(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Crystal structure of a shark single-domain antibody V region in complex with lysozyme."
    Stanfield R.L., Dooley H., Flajnik M.F., Wilson I.A.
    Science 305:1770-1773(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.45 ANGSTROMS).

Entry informationi

Entry nameiQ8AXI4_GINCI
AccessioniPrimary (citable) accession number: Q8AXI4
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: October 29, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3