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Q8AXI4

- Q8AXI4_GINCI

UniProt

Q8AXI4 - Q8AXI4_GINCI

Protein
Submitted name:

Novel antigen receptor

Gene
N/A
Organism
Ginglymostoma cirratum (Nurse shark)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei12 – 121ChlorideImported
    Binding sitei19 – 191Chloride; via amide nitrogenImported

    Keywords - Molecular functioni

    ReceptorImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Novel antigen receptorImported
    OrganismiGinglymostoma cirratum (Nurse shark)Imported
    Taxonomic identifieri7801 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataChondrichthyesElasmobranchiiGaleomorphiiGaleoideaOrectolobiformesGinglymostomatidaeGinglymostoma

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1SQ2X-ray1.45N1-113[»]
    1T6VX-ray1.70N/O1-113[»]
    ProteinModelPortaliQ8AXI4.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ8AXI4.

    Family & Domainsi

    Family and domain databases

    Gene3Di2.60.40.10. 1 hit.
    InterProiIPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003599. Ig_sub.
    IPR013106. Ig_V-set.
    [Graphical view]
    PfamiPF07686. V-set. 1 hit.
    [Graphical view]
    SMARTiSM00409. IG. 1 hit.
    [Graphical view]
    PROSITEiPS50835. IG_LIKE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q8AXI4-1 [UniParc]FASTAAdd to Basket

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    ARVDQTPRSV TKETGESLTI NCVLRDASYA LGSTCWYRKK SGEGNEESIS    50
    KGGRYVETVN SGSKSFSLRI NDLTVEDGGT YRCGLGVAGG YCDYALCSSR 100
    YAECGDGTAV TVN 113
    Length:113
    Mass (Da):12,042
    Last modified:March 1, 2003 - v1
    Checksum:i71522771FEA75661
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei113 – 1131Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF447096 mRNA. Translation: AAN75852.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF447096 mRNA. Translation: AAN75852.1 .

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1SQ2 X-ray 1.45 N 1-113 [» ]
    1T6V X-ray 1.70 N/O 1-113 [» ]
    ProteinModelPortali Q8AXI4.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    EvolutionaryTracei Q8AXI4.

    Family and domain databases

    Gene3Di 2.60.40.10. 1 hit.
    InterProi IPR007110. Ig-like_dom.
    IPR013783. Ig-like_fold.
    IPR003599. Ig_sub.
    IPR013106. Ig_V-set.
    [Graphical view ]
    Pfami PF07686. V-set. 1 hit.
    [Graphical view ]
    SMARTi SM00409. IG. 1 hit.
    [Graphical view ]
    PROSITEi PS50835. IG_LIKE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Selection and characterization of naturally occurring single-domain (IgNAR) antibody fragments from immunized sharks by phage display."
      Dooley H., Flajnik M.F., Porter A.J.
      Mol. Immunol. 40:25-33(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    2. "Crystal structure of a shark single-domain antibody V region in complex with lysozyme."
      Stanfield R.L., Dooley H., Flajnik M.F., Wilson I.A.
      Science 305:1770-1773(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.45 ANGSTROMS).

    Entry informationi

    Entry nameiQ8AXI4_GINCI
    AccessioniPrimary (citable) accession number: Q8AXI4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2003
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3