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Protein

Alpha-(1,3)-fucosyltransferase 11

Gene

FUT11

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Probable fucosyltransferase.By similarity

Pathwayi: protein glycosylation

This protein is involved in the pathway protein glycosylation, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein glycosylation and in Protein modification.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

UniPathwayiUPA00378.

Protein family/group databases

CAZyiGT10. Glycosyltransferase Family 10.

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-(1,3)-fucosyltransferase 11 (EC:2.4.1.-)
Alternative name(s):
Fucosyltransferase XI
Short name:
Fuc-TXI
Short name:
FucT-XI
Galactoside 3-L-fucosyltransferase 11
Short name:
Fucosyltransferase 11
Gene namesi
Name:FUT11
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Unplaced

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 1212CytoplasmicSequence analysisAdd
BLAST
Transmembranei13 – 2917Helical; Signal-anchor for type II membrane proteinSequence analysisAdd
BLAST
Topological domaini30 – 505476LumenalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 505505Alpha-(1,3)-fucosyltransferase 11PRO_0000299012Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi79 – 791N-linked (GlcNAc...)Sequence analysis
Disulfide bondi110 ↔ 115By similarity
Glycosylationi178 – 1781N-linked (GlcNAc...)Sequence analysis
Glycosylationi330 – 3301N-linked (GlcNAc...)Sequence analysis
Disulfide bondi401 ↔ 404By similarity
Glycosylationi483 – 4831N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ8AWC7.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000008285.

Structurei

3D structure databases

ProteinModelPortaliQ8AWC7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 10 family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2619. Eukaryota.
ENOG410ZIMX. LUCA.
HOGENOMiHOG000006538.
HOVERGENiHBG055521.
InParanoidiQ8AWC7.
KOiK11257.
PhylomeDBiQ8AWC7.

Family and domain databases

InterProiIPR017176. Alpha-1_3-FUT_met.
IPR031481. Glyco_tran_10_N.
IPR001503. Glyco_trans_10.
[Graphical view]
PANTHERiPTHR11929. PTHR11929. 1 hit.
PfamiPF17039. Glyco_tran_10_N. 1 hit.
PF00852. Glyco_transf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF037332. Alpha1_3FUT_met. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8AWC7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGGGPGRAA RRGPTCLWVT LALAWGAGSR AAAGDGDGDG EPGPGDAGTP
60 70 80 90 100
CGAEGWARAA VPPGPAFVAA ASYRGPGNND TRSNKALPIL LWWSGSLFPH
110 120 130 140 150
FPGDTERIDC PRGSCLVTRS RRAARHRRTK ALIFYGTDFR AYEAPLPRLP
160 170 180 190 200
HQTWALFHEE SPMNNYLLSH PPGIRLFNYT ATFRRESDYP LTLQWLPGAG
210 220 230 240 250
YLRGPALPLA EKDAWRRRGY GPVLYMQSHC DVPSDRDRYV RELMKYIQVD
260 270 280 290 300
SYGKCLHNRE LPSERLRDTS TATTEDPEFM AFIARYKFHL ALENAICNDY
310 320 330 340 350
MTEKLWRPMH LGAVPVYRGS PAVRDWMPNN LSIILIDDFD SPQELAKYLD
360 370 380 390 400
FLDKNGEEYM KYLEYKNLDG IKNQFLLESL ERREWGVNDM TLPNYLNGFE
410 420 430 440 450
CFICDRENAR VRAEQEHKKS RGKTPAPSPH IAHFQHMGCP MPTPGFGSVE
460 470 480 490 500
DLPGEDSWKE MWLQDYWQSL DQGEALTAMI RHNESHQGRF WDYMHEIFLK

RTRQH
Length:505
Mass (Da):57,516
Last modified:March 1, 2003 - v1
Checksum:iCA5102A0537B37F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ535752 mRNA. Translation: CAD59736.1.
RefSeqiNP_989759.1. NM_204428.1.
UniGeneiGga.4652.

Genome annotation databases

GeneIDi395071.
KEGGigga:395071.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ535752 mRNA. Translation: CAD59736.1.
RefSeqiNP_989759.1. NM_204428.1.
UniGeneiGga.4652.

3D structure databases

ProteinModelPortaliQ8AWC7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000008285.

Protein family/group databases

CAZyiGT10. Glycosyltransferase Family 10.

Proteomic databases

PaxDbiQ8AWC7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi395071.
KEGGigga:395071.

Organism-specific databases

CTDi170384.

Phylogenomic databases

eggNOGiKOG2619. Eukaryota.
ENOG410ZIMX. LUCA.
HOGENOMiHOG000006538.
HOVERGENiHBG055521.
InParanoidiQ8AWC7.
KOiK11257.
PhylomeDBiQ8AWC7.

Enzyme and pathway databases

UniPathwayiUPA00378.

Miscellaneous databases

NextBioi20815164.
PROiQ8AWC7.

Family and domain databases

InterProiIPR017176. Alpha-1_3-FUT_met.
IPR031481. Glyco_tran_10_N.
IPR001503. Glyco_trans_10.
[Graphical view]
PANTHERiPTHR11929. PTHR11929. 1 hit.
PfamiPF17039. Glyco_tran_10_N. 1 hit.
PF00852. Glyco_transf_10. 1 hit.
[Graphical view]
PIRSFiPIRSF037332. Alpha1_3FUT_met. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Cloning expression and genomic organization of a new human alpha3-fucosyltransferase (FUT11)."
    Candelier J.-J., Martinez-Duncker I., Oriol R., Mollicone R.
    Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiFUT11_CHICK
AccessioniPrimary (citable) accession number: Q8AWC7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 21, 2007
Last sequence update: March 1, 2003
Last modified: December 9, 2015
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.