Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Trypsin

Gene

prss1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Serine proteaseUniRule annotation

Enzyme and pathway databases

ReactomeiR-DRE-1442490 Collagen degradation
R-DRE-1592389 Activation of Matrix Metalloproteinases
R-DRE-196741 Cobalamin (Cbl, vitamin B12) transport and metabolism
R-DRE-6798695 Neutrophil degranulation

Protein family/group databases

MEROPSiS01.151

Names & Taxonomyi

Protein namesi
Submitted name:
TrypsinImported
Gene namesi
Name:prss1Imported
Synonyms:tryImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 16

Organism-specific databases

ZFINiZDB-GENE-010131-7 prss1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 15Sequence analysisAdd BLAST15
ChainiPRO_501458881516 – 243Sequence analysisAdd BLAST228

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000042993

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 243Peptidase S1InterPro annotationAdd BLAST219

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00760000118862
HOGENOMiHOG000251820
HOVERGENiHBG013304

Family and domain databases

CDDicd00190 Tryp_SPc, 1 hit
InterProiView protein in InterPro
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
IPR033116 TRYPSIN_SER
PfamiView protein in Pfam
PF00089 Trypsin, 1 hit
PRINTSiPR00722 CHYMOTRYPSIN
SMARTiView protein in SMART
SM00020 Tryp_SPc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
PROSITEiView protein in PROSITE
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit
PS00135 TRYPSIN_SER, 1 hit

Sequencei

Sequence statusi: Complete.

Q8AV83-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKAFILLALF AVAYAAPLGD DDDKIVGGYE CTKNGVPYQV SLNSGYHFCG
60 70 80 90 100
GSLISNLWVV SAAHCYKSRV QVRLGEHNID VTEGTEQFIN SEKVIRHPSY
110 120 130 140 150
NSNTLDNDVM LIKLSSSAQI NSYVKTVSLP SSCASSGTSC LISGWGNMSA
160 170 180 190 200
SGSNYPSRLM CLNAPILSDS TCRNAYPGQI SSNMFCAGFM EGGKDSCQGD
210 220 230 240
SGGPVVCNNQ LQGIVSWGYG CAQRNKPGVY AKVCTSPPGS ETP
Length:243
Mass (Da):25,773
Last modified:March 1, 2003 - v1
Checksum:iDFA4B453FBDA777E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX539313 Genomic DNA No translation available.
CU062628 Genomic DNA No translation available.
AF541952 mRNA Translation: AAO16212.1
UniGeneiDr.75547

Genome annotation databases

EnsembliENSDART00000063125; ENSDARP00000063124; ENSDARG00000042993

Similar proteinsi

Entry informationi

Entry nameiQ8AV83_DANRE
AccessioniPrimary (citable) accession number: Q8AV83
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2003
Last sequence update: March 1, 2003
Last modified: May 23, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health