Q8AAQ0 (CYSD_BACTN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sulfate adenylyltransferase subunit 2
EC=2.7.7.4

Alternative name(s):
ATP-sulfurylase small subunit
Sulfate adenylate transferase
Short name=SAT

Gene names

Name:	cysD
Ordered Locus Names:	BT_0414

Organism

Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

Taxonomic identifier

226186 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	302 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + sulfate = diphosphate + adenylyl sulfate. HAMAP MF_00064
Pathway	Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3. HAMAP MF_00064
Subunit structure	Heterodimer composed of CysD, the smaller subunit, and CysN By similarity.
Sequence similarities	Belongs to the PAPS reductase family. CysD subfamily.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	sulfate reduction Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW sulfate adenylyltransferase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 302	302	Sulfate adenylyltransferase subunit 2 HAMAP MF_00064		PRO_1000092199

Sequences

	Sequence		Length	Mass (Da)
	Q8AAQ0 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: BB352F754932A9BA	FASTA	302	35,520
	10 20 30 40 50 60 MEEYKLSHLK ELEAESIHII REVAAEFENP VMLYSIGKDS SVMVRLAEKA FYPGKVPFPL 70 80 90 100 110 120 MHIDSKWKFK EMIQFRDEYA KKHGWNLIVE SNMEAFHAGV GPFTHGSKVH TDLMKTQALL 130 140 150 160 170 180 HALDKYKFDA AFGGARRDEE KSRAKERIFS FRDKFHQWDP KNQRPELWDI YNARVHKGES 190 200 210 220 230 240 IRVFPISNWT ELDIWQYIRL ENIPIVPLYY AKERPVINLD GNIIMADDDR LPEKYRDQIE 250 260 270 280 290 300 MKMVRFRTLG CWPLTGAVES GAATIEEIVE EMMTTTKSER TTRVIDFDQE GSMEQKKREG YF

References

[1]

"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis." Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I. Science 299:2074-2076(2003) [PubMed: 12663928] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE015928 Genomic DNA. Translation: AAO75521.1.
RefSeq	NP_809327.1. NC_004663.1.
3D structure databases
HSSP	HSSP built from PDB template 1ZUN based on UniProtKB Q87WW0.
ProteinModelPortal	Q8AAQ0.
SMR	Q8AAQ0. Positions 5-211.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1072785.
GenomeReviews	Gene locus BT_0414 in contig AE015928_GR.
KEGG	bth:BT_0414.
NMPDR	fig|226186.1.peg.414.
PATRIC	21055567. VBIBacThe70966_0411.
Phylogenomic databases
HOGENOM	HBG758022.
OMA	HRWDPRN.
PhylomeDB	Q8AAQ0.
ProtClustDB	PRK05253.
Enzyme and pathway databases
BioCyc	BTHE226186:BT_0414-MONOMER.
Family and domain databases
HAMAP	MF_00064. Sulf_adenylyltr_sub2. [Tree]
InterPro	IPR002500. PAPS_reduct. IPR014729. Rossmann-like_a/b/a_fold. IPR011784. SO4_adenylTrfase_ssu. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
KO	K00957.
Pfam	PF01507. PAPS_reduct. 1 hit. [Graphical view]
PIRSF	PIRSF002936. CysDAde_trans. 1 hit.
TIGRFAMs	TIGR02039. CysD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CYSD_BACTN

Accession

Primary (citable) accession number: Q8AAQ0

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 24, 2009
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program