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Q8AAP1

- IF3_BACTN

UniProt

Q8AAP1 - IF3_BACTN

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Protein

Translation initiation factor IF-3

Gene

infC

Organism
Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.UniRule annotation

GO - Molecular functioni

  1. translation initiation factor activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Enzyme and pathway databases

BioCyciBTHE226186:GJXV-424-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-3UniRule annotation
Gene namesi
Name:infCUniRule annotation
Ordered Locus Names:BT_0423
OrganismiBacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Taxonomic identifieri226186 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
ProteomesiUP000001414: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 185185Translation initiation factor IF-3PRO_0000177483Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi226186.BT_0423.

Structurei

3D structure databases

ProteinModelPortaliQ8AAP1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the IF-3 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0290.
InParanoidiQ8AAP1.
KOiK02520.
OMAiKLKHIKR.
OrthoDBiEOG63JRGJ.

Family and domain databases

Gene3Di3.10.20.80. 1 hit.
3.30.110.10. 1 hit.
HAMAPiMF_00080. IF_3.
InterProiIPR019813. Translation_initiation_fac3_CS.
IPR001288. Translation_initiation_fac_3.
IPR019815. Translation_initiation_fac_3_C.
IPR019814. Translation_initiation_fac_3_N.
[Graphical view]
PANTHERiPTHR10938. PTHR10938. 1 hit.
PfamiPF00707. IF3_C. 1 hit.
PF05198. IF3_N. 1 hit.
[Graphical view]
SUPFAMiSSF54364. SSF54364. 1 hit.
SSF55200. SSF55200. 1 hit.
TIGRFAMsiTIGR00168. infC. 1 hit.
PROSITEiPS00938. IF3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8AAP1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKNDTLKGQY RINEQIRAKE VRIVGDEIEP KVYPIFQALK MAEEKELDLV
60 70 80 90 100
EISPNAQPPV CRIIDYSKFL YQLKKRQKEQ KAKQVKVNVK EIRFGPQTDD
110 120 130 140 150
HDYNFKLKHA RGFLEDGDKV KAYVFFKGRS ILFKEQGEVL LLRFANDLED
160 170 180
FAKVDQMPVL EGKRMTIQLS PKKRKCLKNR RLPNR
Length:185
Mass (Da):21,841
Last modified:June 1, 2003 - v1
Checksum:iBE60146914573F09
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE015928 Genomic DNA. Translation: AAO75530.1.
RefSeqiNP_809336.1. NC_004663.1.

Genome annotation databases

EnsemblBacteriaiAAO75530; AAO75530; BT_0423.
GeneIDi1074772.
KEGGibth:BT_0423.
PATRICi21055589. VBIBacThe70966_0422.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE015928 Genomic DNA. Translation: AAO75530.1 .
RefSeqi NP_809336.1. NC_004663.1.

3D structure databases

ProteinModelPortali Q8AAP1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 226186.BT_0423.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO75530 ; AAO75530 ; BT_0423 .
GeneIDi 1074772.
KEGGi bth:BT_0423.
PATRICi 21055589. VBIBacThe70966_0422.

Phylogenomic databases

eggNOGi COG0290.
InParanoidi Q8AAP1.
KOi K02520.
OMAi KLKHIKR.
OrthoDBi EOG63JRGJ.

Enzyme and pathway databases

BioCyci BTHE226186:GJXV-424-MONOMER.

Family and domain databases

Gene3Di 3.10.20.80. 1 hit.
3.30.110.10. 1 hit.
HAMAPi MF_00080. IF_3.
InterProi IPR019813. Translation_initiation_fac3_CS.
IPR001288. Translation_initiation_fac_3.
IPR019815. Translation_initiation_fac_3_C.
IPR019814. Translation_initiation_fac_3_N.
[Graphical view ]
PANTHERi PTHR10938. PTHR10938. 1 hit.
Pfami PF00707. IF3_C. 1 hit.
PF05198. IF3_N. 1 hit.
[Graphical view ]
SUPFAMi SSF54364. SSF54364. 1 hit.
SSF55200. SSF55200. 1 hit.
TIGRFAMsi TIGR00168. infC. 1 hit.
PROSITEi PS00938. IF3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis."
    Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I.
    Science 299:2074-2076(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.

Entry informationi

Entry nameiIF3_BACTN
AccessioniPrimary (citable) accession number: Q8AAP1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: June 1, 2003
Last modified: October 29, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Translation initiation factors
    List of translation initiation factor entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3