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Q8AAP1

- IF3_BACTN

UniProt

Q8AAP1 - IF3_BACTN

Protein

Translation initiation factor IF-3

Gene

infC

Organism
Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 69 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.UniRule annotation

    GO - Molecular functioni

    1. translation initiation factor activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Initiation factor

    Keywords - Biological processi

    Protein biosynthesis

    Enzyme and pathway databases

    BioCyciBTHE226186:GJXV-424-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Translation initiation factor IF-3UniRule annotation
    Gene namesi
    Name:infCUniRule annotation
    Ordered Locus Names:BT_0423
    OrganismiBacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
    Taxonomic identifieri226186 [NCBI]
    Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
    ProteomesiUP000001414: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 185185Translation initiation factor IF-3PRO_0000177483Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi226186.BT_0423.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8AAP1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the IF-3 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0290.
    KOiK02520.
    OMAiKLKHIKR.
    OrthoDBiEOG63JRGJ.

    Family and domain databases

    Gene3Di3.10.20.80. 1 hit.
    3.30.110.10. 1 hit.
    HAMAPiMF_00080. IF_3.
    InterProiIPR019813. Translation_initiation_fac3_CS.
    IPR001288. Translation_initiation_fac_3.
    IPR019815. Translation_initiation_fac_3_C.
    IPR019814. Translation_initiation_fac_3_N.
    [Graphical view]
    PANTHERiPTHR10938. PTHR10938. 1 hit.
    PfamiPF00707. IF3_C. 1 hit.
    PF05198. IF3_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF54364. SSF54364. 1 hit.
    SSF55200. SSF55200. 1 hit.
    TIGRFAMsiTIGR00168. infC. 1 hit.
    PROSITEiPS00938. IF3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8AAP1-1 [UniParc]FASTAAdd to Basket

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    MKNDTLKGQY RINEQIRAKE VRIVGDEIEP KVYPIFQALK MAEEKELDLV    50
    EISPNAQPPV CRIIDYSKFL YQLKKRQKEQ KAKQVKVNVK EIRFGPQTDD 100
    HDYNFKLKHA RGFLEDGDKV KAYVFFKGRS ILFKEQGEVL LLRFANDLED 150
    FAKVDQMPVL EGKRMTIQLS PKKRKCLKNR RLPNR 185
    Length:185
    Mass (Da):21,841
    Last modified:June 1, 2003 - v1
    Checksum:iBE60146914573F09
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015928 Genomic DNA. Translation: AAO75530.1.
    RefSeqiNP_809336.1. NC_004663.1.
    WP_011107263.1. NC_004663.1.

    Genome annotation databases

    EnsemblBacteriaiAAO75530; AAO75530; BT_0423.
    GeneIDi1074772.
    KEGGibth:BT_0423.
    PATRICi21055589. VBIBacThe70966_0422.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015928 Genomic DNA. Translation: AAO75530.1 .
    RefSeqi NP_809336.1. NC_004663.1.
    WP_011107263.1. NC_004663.1.

    3D structure databases

    ProteinModelPortali Q8AAP1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 226186.BT_0423.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAO75530 ; AAO75530 ; BT_0423 .
    GeneIDi 1074772.
    KEGGi bth:BT_0423.
    PATRICi 21055589. VBIBacThe70966_0422.

    Phylogenomic databases

    eggNOGi COG0290.
    KOi K02520.
    OMAi KLKHIKR.
    OrthoDBi EOG63JRGJ.

    Enzyme and pathway databases

    BioCyci BTHE226186:GJXV-424-MONOMER.

    Family and domain databases

    Gene3Di 3.10.20.80. 1 hit.
    3.30.110.10. 1 hit.
    HAMAPi MF_00080. IF_3.
    InterProi IPR019813. Translation_initiation_fac3_CS.
    IPR001288. Translation_initiation_fac_3.
    IPR019815. Translation_initiation_fac_3_C.
    IPR019814. Translation_initiation_fac_3_N.
    [Graphical view ]
    PANTHERi PTHR10938. PTHR10938. 1 hit.
    Pfami PF00707. IF3_C. 1 hit.
    PF05198. IF3_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54364. SSF54364. 1 hit.
    SSF55200. SSF55200. 1 hit.
    TIGRFAMsi TIGR00168. infC. 1 hit.
    PROSITEi PS00938. IF3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis."
      Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I.
      Science 299:2074-2076(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.

    Entry informationi

    Entry nameiIF3_BACTN
    AccessioniPrimary (citable) accession number: Q8AAP1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 15, 2003
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 69 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Translation initiation factors
      List of translation initiation factor entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3