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Q8AAP1 (IF3_BACTN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Translation initiation factor IF-3
Gene names
Name:infC
Ordered Locus Names:BT_0423
OrganismBacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482) [Reference proteome] [HAMAP]
Taxonomic identifier226186 [NCBI]
Taxonomic lineageBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides

Protein attributes

Sequence length185 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins By similarity. HAMAP-Rule MF_00080

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00080

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00080.

Sequence similarities

Belongs to the IF-3 family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   Molecular functionInitiation factor
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiontranslation initiation factor activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 185185Translation initiation factor IF-3 HAMAP-Rule MF_00080
PRO_0000177483

Sequences

Sequence LengthMass (Da)Tools
Q8AAP1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: BE60146914573F09

FASTA18521,841
        10         20         30         40         50         60 
MKNDTLKGQY RINEQIRAKE VRIVGDEIEP KVYPIFQALK MAEEKELDLV EISPNAQPPV 

        70         80         90        100        110        120 
CRIIDYSKFL YQLKKRQKEQ KAKQVKVNVK EIRFGPQTDD HDYNFKLKHA RGFLEDGDKV 

       130        140        150        160        170        180 
KAYVFFKGRS ILFKEQGEVL LLRFANDLED FAKVDQMPVL EGKRMTIQLS PKKRKCLKNR 


RLPNR 

« Hide

References

[1]"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis."
Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I.
Science 299:2074-2076(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE015928 Genomic DNA. Translation: AAO75530.1.
RefSeqNP_809336.1. NC_004663.1.

3D structure databases

ProteinModelPortalQ8AAP1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING226186.BT_0423.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO75530; AAO75530; BT_0423.
GeneID1074772.
KEGGbth:BT_0423.
PATRIC21055589. VBIBacThe70966_0422.

Phylogenomic databases

eggNOGCOG0290.
KOK02520.
OMAKLKHIKR.
OrthoDBEOG63JRGJ.

Enzyme and pathway databases

BioCycBTHE226186:GJXV-424-MONOMER.

Family and domain databases

Gene3D3.10.20.80. 1 hit.
3.30.110.10. 1 hit.
HAMAPMF_00080. IF_3.
InterProIPR019813. Translation_initiation_fac3_CS.
IPR001288. Translation_initiation_fac_3.
IPR019815. Translation_initiation_fac_3_C.
IPR019814. Translation_initiation_fac_3_N.
[Graphical view]
PANTHERPTHR10938. PTHR10938. 1 hit.
PfamPF00707. IF3_C. 1 hit.
PF05198. IF3_N. 1 hit.
[Graphical view]
SUPFAMSSF54364. SSF54364. 1 hit.
SSF55200. SSF55200. 1 hit.
TIGRFAMsTIGR00168. infC. 1 hit.
PROSITEPS00938. IF3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameIF3_BACTN
AccessionPrimary (citable) accession number: Q8AAP1
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: June 1, 2003
Last modified: May 14, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries