Q8A9K7 (Q8A9K7_BACTN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative signal peptidase EMBL AAO75915.1

Gene names

Ordered Locus Names:

BT_0808

Organism

Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

Taxonomic identifier

226186 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	186 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein specifically catalyzes the removal of signal peptides from prolipoproteins By similarity. SAAS SAAS001872
Catalytic activity	Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains. SAAS SAAS001872
Pathway	Protein modification; lipoprotein biosynthesis (signal peptide cleavage). SAAS SAAS001872
Sequence similarities	Belongs to the peptidase A8 family. RuleBase RU004181

Ontologies

Keywords
Cellular component	Cell membrane SAAS SAAS001872 Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS001872
Molecular function	Aspartyl protease SAAS SAAS001872 Hydrolase Protease
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	aspartic-type endopeptidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8A9K7 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 7D8E965E7179F7E7	FASTA	186	21,485
	10 20 30 40 50 60 MYWHESIRVT DWFYIYFTEN NGMAFGMEIF GKLFLTTFRI VAVGLIGYYL YKIIKKGFKT 70 80 90 100 110 120 GYIVCVALIL TGALGNIIDS VFYGVFFNES THSQIASFMP EGGGYSTWFY GKVVDMFYFP 130 140 150 160 170 180 IIDTNWPTWM PFVGGEHFIF FSPIFNFADA AISCGIIALL LFYSKYLNES YHSLDKNKKE SVDHEE

References

[1]

"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis." Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I. Science 299:2074-2076(2003) [PubMed: 12663928] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE015928 Genomic DNA. Translation: AAO75915.1.
RefSeq	NP_809721.1. NC_004663.1.
3D structure databases
ModBase	Search...
Protein family/group databases
MEROPS	A08.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1073632.
GenomeReviews	Gene locus BT_0808 in contig AE015928_GR.
KEGG	bth:BT_0808.
NMPDR	fig|226186.1.peg.808.
PATRIC	21056413. VBIBacThe70966_0826.
Phylogenomic databases
HOGENOM	HBG724422.
OMA	HGKVVDM.
PhylomeDB	Q8A9K7.
ProtClustDB	PRK14788.
Family and domain databases
InterPro	IPR001872. Peptidase_A8. [Graphical view]
KO	K03101.
Pfam	PF01252. Peptidase_A8. 1 hit. [Graphical view]
PRINTS	PR00781. LIPOSIGPTASE.
ProtoNet	Search...

Entry information

Entry name

Q8A9K7_BACTN

Accession

Primary (citable) accession number: Q8A9K7

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)