Q8A9C0 (Q8A9C0_BACTN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrodipicolinate synthase EMBL AAO76002.1

Gene names

Ordered Locus Names:

BT_0895

Organism

Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

Taxonomic identifier

226186 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	297 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-aspartate 4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H2O. SAAS SAAS005263
Pathway	Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4. SAAS SAAS005263
Subunit structure	Homotetramer By similarity. SAAS SAAS005263
Subcellular location	Cytoplasm By similarity SAAS SAAS005263.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Diaminopimelate biosynthesis SAAS SAAS005263 Lysine biosynthesis SAAS SAAS005263
Cellular component	Cytoplasm SAAS SAAS005263
Ligand	Schiff base SAAS SAAS005263
Molecular function	Lyase SAAS SAAS005263
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	diaminopimelate biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	dihydrodipicolinate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8A9C0 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 5C0D3F7D70A625AA	FASTA	297	32,810
	10 20 30 40 50 60 MIQTKLKGMG VALITPFKED ESVDYDALMR LVDYLLQNNA DFLCVLGTTA ETPTLTEEEK 70 80 90 100 110 120 KTIKKMVIDR VNGRIPILLG VGGNNTRAIV ETLKNDDFTG VDAILSVVPY YNKPSQEGIY 130 140 150 160 170 180 QHYKAISEAT ELPIVLYNVP GRTGVNMTAE TTLRIARNFS NVIAIKEASG NITQMDDIIK 190 200 210 220 230 240 NKPDNFNVIS GDDGITFPLI TLGAVGVISV IGNAFPREFS RMTRLALQGD FANALTIHHR 250 260 270 280 290 FTELFDLLFV DGNPAGVKSM LNAMGMIENK LRLPLVPTRI TTFEAIRKVL NELNIKC

References

[1]

"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis." Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I. Science 299:2074-2076(2003) [PubMed: 12663928] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE015928 Genomic DNA. Translation: AAO76002.1.
RefSeq	NP_809808.1. NC_004663.1.
3D structure databases
HSSP	HSSP built from PDB template 1O5K based on UniProtKB Q9X1K9.
ProteinModelPortal	Q8A9C0.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1074492.
GenomeReviews	Gene locus BT_0895 in contig AE015928_GR.
KEGG	bth:BT_0895.
NMPDR	fig|226186.1.peg.895.
PATRIC	21056583. VBIBacThe70966_0907.
Phylogenomic databases
HOGENOM	HBG358848.
OMA	CEMEDSN.
PhylomeDB	Q8A9C0.
ProtClustDB	PRK03170.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR002220. Dihydrodipicolinate_synth-like. IPR020625. Dihydrodipicolinate_synth_AS. IPR005263. Dihydrodipicolinate_synth_DapA. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01714.
PANTHER	PTHR12128. DHDPS. 1 hit.
Pfam	PF00701. DHDPS. 1 hit. [Graphical view]
PIRSF	PIRSF001365. DHDPS. 1 hit.
PRINTS	PR00146. DHPICSNTHASE.
TIGRFAMs	TIGR00674. DapA. 1 hit.
PROSITE	PS00666. DHDPS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8A9C0_BACTN

Accession

Primary (citable) accession number: Q8A9C0

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)