Q8A997 (GCP_BACTN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	BT_0920

Organism

Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

Taxonomic identifier

226186 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	339 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 339	339	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303273

Sequences

	Sequence		Length	Mass (Da)
	Q8A997 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 60C5904913EFCC9A	FASTA	339	36,774
	10 20 30 40 50 60 MSAIILGIES SCDDTSAAVI KDGYLLSNVV SSQAVHEAYG GVVPELASRA HQQNIVPVVH 70 80 90 100 110 120 EALKRAGVTK EELSAVAFTR GPGLMGSLLV GVSFAKGFAR SLGIPLIDVN HLTGHVLAHF 130 140 150 160 170 180 IKAEGEENIQ PKFPFLCLLV SGGNSQIILV KAYNDMEILG QTIDDAAGEA IDKCSKVMGL 190 200 210 220 230 240 GYPGGPIIDK LARQGNPKAY TFSKPHIPGL DYSFSGLKTS FLYSLRDWMK DDPDFIEHHK 250 260 270 280 290 300 VDLAASLEAT VVDILMDKLR KAAKEYKIKE VAVAGGVSAN NGLRNSFREH AEKYGWNIFI 310 320 330 PKFSYTTDNA AMIAITGYFK YLDKDFCSID LPAYSRVTL

References

[1]

"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis." Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I. Science 299:2074-2076(2003) [PubMed: 12663928] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE015928 Genomic DNA. Translation: AAO76027.1.
RefSeq	NP_809833.1. NC_004663.1.
3D structure databases
ProteinModelPortal	Q8A997.
ModBase	Search...
Protein family/group databases
MEROPS	M22.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1073463.
GenomeReviews	Gene locus BT_0920 in contig AE015928_GR.
KEGG	bth:BT_0920.
NMPDR	fig|226186.1.peg.920.
PATRIC	21056641. VBIBacThe70966_0933.
Phylogenomic databases
HOGENOM	HBG304663.
OMA	MEVIGQT.
PhylomeDB	Q8A997.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	BTHE226186:BT_0920-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_BACTN

Accession

Primary (citable) accession number: Q8A997

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program