Beta-galactosidase - Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

Preferred order of sections

Names and origin

Protein names

Submitted name:
Beta-galactosidase EMBL AAO76733.1

Gene names

Ordered Locus Names:

Organism

Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482) [Reference proteome] [HAMAP] EMBL AAO76733.1

Taxonomic identifier

226186 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides ›

Protein attributes

Sequence length	1022 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. SAAS SAAS013812

Ontologies

Keywords
Ligand	Magnesium PDB 3BGA Metal-binding PDB 3BGA
Molecular function	Glycosidase SAAS SAAS023230 Hydrolase
Technical term	3D-structure PDB 3BGA Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	beta-galactosidase complex Inferred from electronic annotation. Source: InterPro
Molecular_function	beta-galactosidase activity Inferred from electronic annotation. Source: InterPro carbohydrate binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Sites

Metal binding

438

1

Magnesium PDB 3BGA

Metal binding

440

1

Magnesium; via pros nitrogen PDB 3BGA

Metal binding

484

1

Magnesium PDB 3BGA

Sequences

Sequence

Length

Mass (Da)

Tools

Q8A799 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 57CE3BF43338F6A2
Show »

FASTA

1,022

116,257

        10         20         30         40         50         60 
MKLKKRTFLI LMAALTATFA SAQKQPLPEW QSQYAVGLNK LAPHTYVWPY ADASDIGKPG 

        70         80         90        100        110        120 
GYEQSPYYMS LNGKWKFNWV KNPDNRPKDF YQPSYYTGGW ADINVPGNWE RQGYGTAIYV 

       130        140        150        160        170        180 
NETYEFDDKM FNFKKNPPLV PFAENEVGSY RRTFKVPADW KGRRVVLCCE GVISFYYVWV 

       190        200        210        220        230        240 
NGKLLGYNQG SKTAAEWDIT DVLSEGENVV ALEVYRWSSG AYLECQDMWR LSGIERDVYL 

       250        260        270        280        290        300 
YSTPKQYIAD YKVSASLDKE KYKEGIFNLE VTVEGPSATA SSIAYTLKDA SGKAVLQDAI 

       310        320        330        340        350        360 
NIKSRGLSNF IAFDEKKIAE VKAWNAEHPN LYTLVLELKD AQGKVTELTG CEVGFRTSEI 

       370        380        390        400        410        420 
KDGRFCINGV PVLVKGTNRH EHSQLGRTVS KELMEQDIRL MKQHNINMVR NSHYPTHPYW 

       430        440        450        460        470        480 
YQLCDRYGLY MIDEANIESH GMGYGPASLA KDSTWLTAHM DRTHRMYERS KNHPAIVIWS 

       490        500        510        520        530        540 
QGNEAGNGIN FERTYDWLKS VEKGRPVQYE RAELNYNTDI YCRMYRSVDE IKAYVGKKDI 

       550        560        570        580        590        600 
YRPFILCEYL HAMGNSCGGM KEYWEVFENE PMAQGGCIWD WVDQNFREID KDGKWYWTYG 

       610        620        630        640        650        660 
GDYGPEGIPS FGNFCGNGLV NAVREPHPHL LEVKKIYQNI KATLSDRKNL KVCIKNWYDF 

       670        680        690        700        710        720 
SNLNEYILRW NVKGEDGTVL AEGTKEVDCE PHATVDVTLG AVKLPNTVRE AYLNLSWSRK 

       730        740        750        760        770        780 
EATPLVDTDW EVAYDQFVLA GNKNTTAYRP QKAGETAFVV DKNTGALSSL TLDGKELLAA 

       790        800        810        820        830        840 
PITLSLFRPA TDNDNRDRNG ARLWRKAGLN NLTQKVVSLK EEKTSATVRA EILNGKGQKV 

       850        860        870        880        890        900 
GMADFVYALD KNGALKVRTT FQPDTAIVKS MARLGLTFRM ADAYNQVSYL GRGDHETYID 

       910        920        930        940        950        960 
RNQSGRIGLY DTTVERMFHY YATPQSTANR TDVRWAKLTD QAGEGVFMES NRPFQFSIIP 

       970        980        990       1000       1010       1020 
FSDVLLEKAH HINELERDGM ITIHLDAEQA GVGTATCGPG VLPQYLVPVK KQSFEFTLYP 


VK

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis." Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I. Science 299:2074-2076(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.
[2]	"Crystal structure analysis of beta-galactosidase from Bacteroides thetaiotaomicron VPI-5482." Kumaran D., Burley S.K., Swaminathan S. Submitted (NOV-2007) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) OF 24-1022 IN COMPLEX WITH MAGNESIUM.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE015928 Genomic DNA. Translation: AAO76733.1.

RefSeq

NP_810539.1. NC_004663.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3BGA	X-ray	2.10	A/B	24-1022	[»]

ProteinModelPortal

Q8A799.

SMR

Q8A799. Positions 24-1022.

ModBase

Search...

Protein-protein interaction databases

STRING

226186.BT_1626.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

AAO76733; AAO76733; BT_1626.

GeneID

1075755.

KEGG

bth:BT_1626.

PATRIC

21058136. VBIBacThe70966_1664.

Phylogenomic databases

KO

K01190.

OMA

NSHYPTH.

ProtClustDB

CLSK822807.

Enzyme and pathway databases

BioCyc

BTHE226186:GJXV-1658-MONOMER.

Family and domain databases

Gene3D

2.60.40.320. 2 hits.
2.70.98.10. 1 hit.
3.20.20.80. 1 hit.

InterPro

IPR004199. B-gal_small/dom_5.
IPR011013. Gal_mutarotase_SF_dom.
IPR008979. Galactose-bd-like.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR023230. Glyco_hydro_2_CS.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]

Pfam

PF02929. Bgal_small_N. 1 hit.
PF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view]

PRINTS

PR00132. GLHYDRLASE2.

SMART

SM01038. Bgal_small_N. 1 hit.
[Graphical view]

SUPFAM

SSF49785. Gal_bind_like. 1 hit.
SSF74650. Gal_mut_like. 1 hit.
SSF49303. Glyco_hydro_2Ig. 2 hits.
SSF51445. Glyco_hydro_cat. 1 hit.

PROSITE

PS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q8A799.

Entry information

Entry name

Q8A799_BACTN

Accession

Primary (citable) accession number: Q8A799

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	May 1, 2013
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)