Q8A767 (TAL_BACTN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable transaldolase
EC=2.2.1.2

Gene names

Name:	tal
Ordered Locus Names:	BT_1658

Organism

Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

Taxonomic identifier

226186 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	218 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity. HAMAP MF_00494
Catalytic activity	Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP MF_00494
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP MF_00494
Subcellular location	Cytoplasm By similarity HAMAP MF_00494.
Sequence similarities	Belongs to the transaldolase family. Type 3B subfamily.

Ontologies

Keywords
Biological process	Pentose shunt
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 218	218	Probable transaldolase HAMAP MF_00494		PRO_0000173659
Sites
	Active site	87	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8A767 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 3FC4F3516694DA94	FASTA	218	23,775
	10 20 30 40 50 60 MKFFIDTANL EQIQEAYDLG VLDGVTTNPS LMAKEGIKGT ENQREHYIKI CKIVNADVSA 70 80 90 100 110 120 EVIATDYEGM IREGEELAAL NPHIVVKVPC IADGIKAIKY FTEKGIRTNC TLVFSVGQAL 130 140 150 160 170 180 LAAKAGATYV SPFVGRLDDI CEDGVGLVGD IVRMYRTYDY KTQVLAASIR NTKHIIECVE 190 200 210 VGADVATCPL SAIKGLLNHP LTDSGLKKFL EDYKKVNG

References

[1]

"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis." Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I. Science 299:2074-2076(2003) [PubMed: 12663928] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE015928 Genomic DNA. Translation: AAO76765.1.
RefSeq	NP_810571.1. NC_004663.1.
3D structure databases
ProteinModelPortal	Q8A767.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1075635.
GenomeReviews	Gene locus BT_1658 in contig AE015928_GR.
KEGG	bth:BT_1658.
NMPDR	fig|226186.1.peg.1658.
PATRIC	21058206. VBIBacThe70966_1699.
Phylogenomic databases
HOGENOM	HBG533000.
OMA	KVNVTLC.
PhylomeDB	Q8A767.
ProtClustDB	PRK01362.
Enzyme and pathway databases
BioCyc	BTHE226186:BT_1658-MONOMER.
Family and domain databases
HAMAP	MF_00494. Transaldolase_3b. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001585. Transaldolase. IPR004731. Transaldolase_3A/3B. IPR022999. Transaldolase_3B. IPR018225. Transaldolase_AS. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K00616.
PANTHER	PTHR10683. Transaldolase. 1 hit.
Pfam	PF00923. Transaldolase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00875. Fsa_talC_mipB. 1 hit.
PROSITE	PS01054. TRANSALDOLASE_1. 1 hit. PS00958. TRANSALDOLASE_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TAL_BACTN

Accession

Primary (citable) accession number: Q8A767

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 16, 2004
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program