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Q8A5W2

- G6PI_BACTN

UniProt

Q8A5W2 - G6PI_BACTN

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Protein
Glucose-6-phosphate isomerase
Gene
pgi, BT_2124
Organism
Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei287 – 2871Proton donor By similarity
Active sitei308 – 3081 By similarity
Active sitei422 – 4221 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciBTHE226186:GJXV-2164-MONOMER.
UniPathwayiUPA00109; UER00181.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:BT_2124
OrganismiBacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Taxonomic identifieri226186 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
ProteomesiUP000001414: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 445445Glucose-6-phosphate isomeraseUniRule annotation
PRO_0000180597Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi226186.BT_2124.

Structurei

3D structure databases

ProteinModelPortaliQ8A5W2.
SMRiQ8A5W2. Positions 2-445.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiANMFKIL.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8A5W2-1 [UniParc]FASTAAdd to Basket

« Hide

MISLNIEKTF GFISKEKVSA YEAEVKAAQE MLEKGTGEGN DFLGWLHLPS    50
SISKEHLADL NATAKVLRDN CEVVIVAGIG GSYLGARAVI EALSNSFTWL 100
QDKKTAPVMI YAGHNISEDY LYELTEYLKD KKFGVINISK SGTTTETALA 150
FRLLKKQCED QRGKETAKKV IVAVTDAKKG AARVTADKEG YKTFIIPDNV 200
GGRFSVLTPV GLLPIAVAGF DIDKLVAGAA DMEKACGSDV PFAENPAAIY 250
AATRNELYRQ GKKIEILVNF CPKLHYVSEW WKQLYGESEG KDNKGIFPAS 300
VDFSTDLHSM GQWIQEGERS IFETVISLDK VDHKLEVPFD EANLDGLNFL 350
AGKRVDEVNK MAELGTQLAH VDGGVPNMRI VLPELSEYNI GGLLYFFEKA 400
CGISGYLLGV NPFNQPGVEA YKKNMFALLN KPGYEEESKA IQAKL 445
Length:445
Mass (Da):48,891
Last modified:May 23, 2003 - v1
Checksum:iC80209EA1A7E63AA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE015928 Genomic DNA. Translation: AAO77231.1.
RefSeqiNP_811037.1. NC_004663.1.

Genome annotation databases

EnsemblBacteriaiAAO77231; AAO77231; BT_2124.
GeneIDi1075192.
KEGGibth:BT_2124.
PATRICi21059198. VBIBacThe70966_2186.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE015928 Genomic DNA. Translation: AAO77231.1 .
RefSeqi NP_811037.1. NC_004663.1.

3D structure databases

ProteinModelPortali Q8A5W2.
SMRi Q8A5W2. Positions 2-445.
ModBasei Search...

Protein-protein interaction databases

STRINGi 226186.BT_2124.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO77231 ; AAO77231 ; BT_2124 .
GeneIDi 1075192.
KEGGi bth:BT_2124.
PATRICi 21059198. VBIBacThe70966_2186.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000100403.
KOi K01810.
OMAi ANMFKIL.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
BioCyci BTHE226186:GJXV-2164-MONOMER.

Family and domain databases

HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis."
    Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I.
    Science 299:2074-2076(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.

Entry informationi

Entry nameiG6PI_BACTN
AccessioniPrimary (citable) accession number: Q8A5W2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 23, 2003
Last sequence update: May 23, 2003
Last modified: June 11, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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