Q8A5Q2 (Q8A5Q2_BACTN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
3-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210 RuleBase RU000531
EC=2.5.1.19 HAMAP MF_00210 RuleBase RU000531

Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase HAMAP MF_00210

Gene names

Name:	aroA HAMAP MF_00210
Ordered Locus Names:	BT_2186

Organism

Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

Taxonomic identifier

226186 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	410 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210 RuleBase RU000531
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210
Subunit structure	Monomer By similarity. HAMAP MF_00210
Subcellular location	Cytoplasm By similarity HAMAP MF_00210.
Sequence similarities	Belongs to the EPSP synthase family. HAMAP MF_00210 RuleBase RU004164

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00210 RuleBase RU000531
Cellular component	Cytoplasm HAMAP MF_00210
Molecular function	Transferase HAMAP MF_00210 RuleBase RU000531 EMBL AAO77293.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-phosphoshikimate 1-carboxyvinyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8A5Q2 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 6A70F9049ADBA4FB	FASTA	410	45,278
	10 20 30 40 50 60 MMLYKLISPS MVKATIQLPA SKSISNRALI INALGKGIYP PENLSDCDDT QVMIKALTEG 70 80 90 100 110 120 KETIDIMAAG TAMRFLTAYL SATSGERIIT GTARMQQRPI QILVNALREL GAEIEYTHNE 130 140 150 160 170 180 GYPPLRIKGA ELKGNEITLK GNVSSQYISA LLMIGPVLKD GLTLHLTGEI ISRPYINLTL 190 200 210 220 230 240 QLMQDFGAKA AWTSPSSISV APQPYQSVPF TVESDWSAAS YWYQIAALSP EAEIELLGLF 250 260 270 280 290 300 RNSYQGDSRG AEVFSRLGIT TEFTPKGVKI KKTGKTPERL EEDFVDIPDL AQTFVVTCAL 310 320 330 340 350 360 LNIPFRFTGL QSLKIKETDR IAALRTELKK LGYLIEEEND SVLMWNGERC EPEAVPVIAT 370 380 390 400 410 YEDHRMAMAF APAVITFPKL LIADPQVVSK SYPGYWEDLK LAGFQVINEG

References

[1]

"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis." Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I. Science 299:2074-2076(2003) [PubMed: 12663928] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE015928 Genomic DNA. Translation: AAO77293.1.
RefSeq	NP_811099.1. NC_004663.1.
3D structure databases
HSSP	HSSP built from PDB template 1Q36 based on UniProtKB P07638.
ProteinModelPortal	Q8A5Q2.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1075243.
GenomeReviews	Gene locus BT_2186 in contig AE015928_GR.
KEGG	bth:BT_2186.
NMPDR	fig|226186.1.peg.2186.
PATRIC	21059328. VBIBacThe70966_2250.
Phylogenomic databases
HOGENOM	HBG646626.
OMA	ERKSWSF.
PhylomeDB	Q8A5Q2.
ProtClustDB	CLSK2757416.
Family and domain databases
HAMAP	MF_00210. EPSP_synth. [Tree]
InterPro	IPR001986. Enolpyruvate_Tfrase_dom. IPR006264. EPSP_synthase. IPR023193. EPSP_synthase_CS. IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b. [Graphical view]
Gene3D	G3DSA:3.65.10.10. EPSP_synthase. 3 hits.
KO	K00800.
Pfam	PF00275. EPSP_synthase. 2 hits. [Graphical view]
PIRSF	PIRSF000505. EPSPS. 1 hit.
SUPFAM	SSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMs	TIGR01356. AroA. 1 hit.
PROSITE	PS00885. EPSP_SYNTHASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8A5Q2_BACTN

Accession

Primary (citable) accession number: Q8A5Q2

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)