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Q8A5G6 (Q8A5G6_BACTN) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribosomal RNA small subunit methyltransferase I HAMAP MF_01877
EC=2.1.1.198 HAMAP MF_01877
Alternative name(s):
16S rRNA 2'-O-ribose C1402 methyltransferase HAMAP MF_01877
rRNA (cytidine-2'-O-)-methyltransferase RsmI HAMAP MF_01877
Gene names
Name:rsmI HAMAP MF_01877
Ordered Locus Names:BT_2273
OrganismBacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Taxonomic identifier226186 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length224 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA By similarity. HAMAP MF_01877

Catalytic activity

S-adenosyl-L-methionine + cytosine(1402) in 16S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytosine(1402) in 16S rRNA. HAMAP MF_01877

Subcellular location

Cytoplasm By similarity HAMAP MF_01877.

Sequence similarities

Belongs to the methyltransferase superfamily. RsmI family. HAMAP MF_01877

Sequences

Sequence LengthMass (Da)Tools
Q8A5G6 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 7B054492BD1F0541

FASTA22424,912
        10         20         30         40         50         60 
MGKLYVVPTP VGNLEDMTFR AIRVLKEVDL ILAEDTRTSG ILLKHFEIKN AMQSHHKFNE 

        70         80         90        100        110        120 
HKTVESVVNR IKAGETVALI SDAGTPGISD PGFLVVRECV RNGIEVQCLP GATAFVPALV 

       130        140        150        160        170        180 
ASGLPNEKFC FEGFLPQKKG RQTRLKALAE EHRTMVFYES PHRLLKTLTQ FAEYFGTERQ 

       190        200        210        220 
ATVSREISKL HEETVRGSLA ELIEHFTATE PRGEIVIVLA GIDD

« Hide

References

« Hide 'large scale' references
[1]"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis."
Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I.
Science 299:2074-2076(2003) [PubMed: 12663928] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.
[2]"The crystal structure of a methyltransferase domain from Bacteroides thetaiotaomicron VPI."
Tan K., Tesar C., Cobb G., Joachimiak A.
Submitted (JAN-2009) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.36 ANGSTROMS) OF 113-224.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE015928 Genomic DNA. Translation: AAO77380.1.
RefSeqNP_811186.1. NC_004663.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3FQ6X-ray2.36A/B113-224[»]
ProteinModelPortalQ8A5G6.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1076108.
GenomeReviewsGene locus BT_2273 in contig AE015928_GR.
KEGGbth:BT_2273.
NMPDRfig|226186.1.peg.2273.
PATRIC21059501. VBIBacThe70966_2336.

Phylogenomic databases

HOGENOMHBG529058.
OMAGREMTKI.
PhylomeDBQ8A5G6.
ProtClustDBCLSK823102.

Family and domain databases

HAMAPMF_01877. 16SrRNA_methyltr_I.
[Tree]
InterProIPR000878. 4pyrrol_Mease.
IPR014777. 4pyrrole_Mease_sub1.
IPR014776. 4pyrrole_Mease_sub2.
IPR008189. rRNA_ssu_MeTfrase_I.
IPR018063. SAM_MeTrfase_RsmI_CS.
[Graphical view]
Gene3DG3DSA:3.40.1010.10. 4pyrrole_Mease_sub1. 1 hit.
G3DSA:3.30.950.10. 4pyrrole_Mease_sub2. 1 hit.
KOK07056.
PANTHERPTHR21091:SF18. PTHR21091:SF18. 1 hit.
PfamPF00590. TP_methylase. 1 hit.
[Graphical view]
PIRSFPIRSF005917. MTase_YraL. 1 hit.
SUPFAMSSF53790. Cor/por_Metransf. 1 hit.
TIGRFAMsTIGR00096. TIGR00096. 1 hit.
PROSITEPS01296. RSMI. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ8A5G6_BACTN
AccessionPrimary (citable) accession number: Q8A5G6
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: January 25, 2012
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info