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Protein

Glutamate decarboxylase

Gene

BT_2570

Organism
Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciBTHE:G13PU-7520-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:BT_2570Imported
OrganismiBacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)Imported
Taxonomic identifieri226186 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
Proteomesi
  • UP000001414 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei274N6-(pyridoxal phosphate)lysineUniRule annotation1

Proteomic databases

PaxDbiQ8A4M9
PRIDEiQ8A4M9

Interactioni

Protein-protein interaction databases

STRINGi226186.BT_2570

Structurei

3D structure databases

ProteinModelPortaliQ8A4M9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CVK Bacteria
COG0076 LUCA
InParanoidiQ8A4M9
KOiK01580
OMAiRPNLVMG
OrthoDBiPOG091H06F5

Family and domain databases

Gene3Di3.40.640.10, 1 hit
InterProiView protein in InterPro
IPR010107 Glutamate_decarboxylase
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
PANTHERiPTHR43321 PTHR43321, 1 hit
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR01788 Glu-decarb-GAD, 1 hit

Sequencei

Sequence statusi: Complete.

Q8A4M9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDLNFRKGD AKTDVFGSDR MLQPSPVERI PDGPTTPEVA YQMVKDETFA
60 70 80 90 100
QTQPRLNLAT FVTTYMDDYA TKLMNEAINI NYIDETEYPR IAVMNGKCIN
110 120 130 140 150
IVANLWNSPE KDTWKTGALA IGSSEACMLG GVAAWLRWRK KRQAQGKPFD
160 170 180 190 200
KPNFVISTGF QVVWEKFAQL WQIEMREVPL TLEKTTLDPE EALKMCDENT
210 220 230 240 250
ICVVPIQGVT WTGLNDDVEA LDKALDAYNA KTGYDIPIHV DAASGGFILP
260 270 280 290 300
FLYPDTKWDF RLKWVLSISV SGHKFGLVYP GLGWVCWKGK EYLPEEMSFS
310 320 330 340 350
VNYLGANITQ VGLNFSRPAA QILGQYYQFI RLGFQGYKEV QYNSLQIAKY
360 370 380 390 400
IHGEIAKMAP FVNYSENVVN PLFIWYLKPE YAKSAKWTLY DLQDKLSQHG
410 420 430 440 450
WMVPAYTLPS KLEDYVVMRV VVRQGFSRDM ADMLLGDIKN AIAELEKLDF
460 470 480
PTPTRMAQEK NLPVEAKMFN HGGRRHKTVK K
Length:481
Mass (Da):54,854
Last modified:June 1, 2003 - v1
Checksum:i2E9B278043D23AD2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015928 Genomic DNA Translation: AAO77677.1
RefSeqiNP_811483.1, NC_004663.1
WP_011108358.1, NC_004663.1

Genome annotation databases

EnsemblBacteriaiAAO77677; AAO77677; BT_2570
GeneIDi1072177
31618833
KEGGibth:BT_2570
PATRICifig|226186.12.peg.2622

Similar proteinsi

Entry informationi

Entry nameiQ8A4M9_BACTN
AccessioniPrimary (citable) accession number: Q8A4M9
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health