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Q8A4M9

- Q8A4M9_BACTN

UniProt

Q8A4M9 - Q8A4M9_BACTN

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Protein

Glutamate decarboxylase

Gene

BT_2570

Organism
Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

Note: Pyridoxal phosphate.UniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciBTHE226186:GJXV-2618-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:BT_2570Imported
OrganismiBacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)Imported
Taxonomic identifieri226186 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
ProteomesiUP000001414: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi226186.BT_2570.

Structurei

3D structure databases

ProteinModelPortaliQ8A4M9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

InParanoidiQ8A4M9.
KOiK01580.
OMAiVHAKMAS.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8A4M9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEDLNFRKGD AKTDVFGSDR MLQPSPVERI PDGPTTPEVA YQMVKDETFA
60 70 80 90 100
QTQPRLNLAT FVTTYMDDYA TKLMNEAINI NYIDETEYPR IAVMNGKCIN
110 120 130 140 150
IVANLWNSPE KDTWKTGALA IGSSEACMLG GVAAWLRWRK KRQAQGKPFD
160 170 180 190 200
KPNFVISTGF QVVWEKFAQL WQIEMREVPL TLEKTTLDPE EALKMCDENT
210 220 230 240 250
ICVVPIQGVT WTGLNDDVEA LDKALDAYNA KTGYDIPIHV DAASGGFILP
260 270 280 290 300
FLYPDTKWDF RLKWVLSISV SGHKFGLVYP GLGWVCWKGK EYLPEEMSFS
310 320 330 340 350
VNYLGANITQ VGLNFSRPAA QILGQYYQFI RLGFQGYKEV QYNSLQIAKY
360 370 380 390 400
IHGEIAKMAP FVNYSENVVN PLFIWYLKPE YAKSAKWTLY DLQDKLSQHG
410 420 430 440 450
WMVPAYTLPS KLEDYVVMRV VVRQGFSRDM ADMLLGDIKN AIAELEKLDF
460 470 480
PTPTRMAQEK NLPVEAKMFN HGGRRHKTVK K
Length:481
Mass (Da):54,854
Last modified:June 1, 2003 - v1
Checksum:i2E9B278043D23AD2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015928 Genomic DNA. Translation: AAO77677.1.
RefSeqiNP_811483.1. NC_004663.1.
WP_011108358.1. NC_004663.1.

Genome annotation databases

EnsemblBacteriaiAAO77677; AAO77677; BT_2570.
GeneIDi1072177.
KEGGibth:BT_2570.
PATRICi21060087. VBIBacThe70966_2622.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015928 Genomic DNA. Translation: AAO77677.1 .
RefSeqi NP_811483.1. NC_004663.1.
WP_011108358.1. NC_004663.1.

3D structure databases

ProteinModelPortali Q8A4M9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 226186.BT_2570.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAO77677 ; AAO77677 ; BT_2570 .
GeneIDi 1072177.
KEGGi bth:BT_2570.
PATRICi 21060087. VBIBacThe70966_2622.

Phylogenomic databases

InParanoidi Q8A4M9.
KOi K01580.
OMAi VHAKMAS.
OrthoDBi EOG6TFCPW.

Enzyme and pathway databases

BioCyci BTHE226186:GJXV-2618-MONOMER.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
InterProi IPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
Pfami PF00282. Pyridoxal_deC. 1 hit.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 1 hit.
TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis."
    Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I.
    Science 299:2074-2076(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: VPI-5482Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482Imported.

Entry informationi

Entry nameiQ8A4M9_BACTN
AccessioniPrimary (citable) accession number: Q8A4M9
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: November 26, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3