Q8A4A1 (RS4_BACTN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
30S ribosomal protein S4

Gene names

Name:	rpsD
Ordered Locus Names:	BT_2702

Organism

Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

Taxonomic identifier

226186 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	201 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit By similarity. HAMAP MF_01306_B With S5 and S12 plays an important role in translational accuracy By similarity. HAMAP MF_01306_B
Subunit structure	Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity By similarity.
Sequence similarities	Belongs to the ribosomal protein S4P family. Contains 1 S4 RNA-binding domain.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	small ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 201	201	30S ribosomal protein S4 HAMAP MF_01306_B		PRO_0000132340
Regions
	Domain	92 – 155	64	S4 RNA-binding

Sequences

	Sequence		Length	Mass (Da)
	Q8A4A1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 2B5F6C9C6DA389D7	FASTA	201	22,597
	10 20 30 40 50 60 MARYTGPKSR IARKFGEGIF GADKVLSKKN YPPGQHGNSR KRKTSEYGVQ LREKQKAKYT 70 80 90 100 110 120 YGVLEKQFRN LFEKAATAKG ITGEVLLQLL EGRLDNVVFR LGIAPTRAAA RQLVSHKHIT 130 140 150 160 170 180 VDGEVVNIPS FAVKPGQLIG VRERSKSLEV IANSLAGFNH SKYAWLEWDE TSKVGKMLHI 190 200 PERADIPENI KEHLIVELYS K

References

[1]

"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis." Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I. Science 299:2074-2076(2003) [PubMed: 12663928] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE015928 Genomic DNA. Translation: AAO77808.1.
RefSeq	NP_811614.1. NC_004663.1.
3D structure databases
ProteinModelPortal	Q8A4A1.
SMR	Q8A4A1. Positions 2-201.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1072470.
GenomeReviews	Gene locus BT_2702 in contig AE015928_GR.
KEGG	bth:BT_2702.
NMPDR	fig|226186.1.peg.2701.
PATRIC	21060345. VBIBacThe70966_2744.
Phylogenomic databases
HOGENOM	HBG285740.
OMA	QLVVELY.
PhylomeDB	Q8A4A1.
ProtClustDB	PRK05327.
Enzyme and pathway databases
BioCyc	BTHE226186:BT_2702-MONOMER.
Family and domain databases
HAMAP	MF_01306_B. Ribosomal_S4_B. [Tree]
InterPro	IPR022801. Ribosomal_S4/S9. IPR001912. Ribosomal_S4/S9_N. IPR005709. Ribosomal_S4_bac-type. IPR018079. Ribosomal_S4_CS. IPR002942. S4_RNA-bd. [Graphical view]
Gene3D	G3DSA:1.10.1050.10. G3DSA:1.10.1050.10. 1 hit. G3DSA:3.10.290.10. G3DSA:3.10.290.10. 1 hit.
KO	K02986.
PANTHER	PTHR11831. Ribosomal_S4. 1 hit.
Pfam	PF00163. Ribosomal_S4. 1 hit. PF01479. S4. 1 hit. [Graphical view]
SMART	SM00363. S4. 1 hit. [Graphical view]
TIGRFAMs	TIGR01017. RpsD_bact. 1 hit.
PROSITE	PS00632. RIBOSOMAL_S4. 1 hit. PS50889. S4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RS4_BACTN

Accession

Primary (citable) accession number: Q8A4A1

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 16, 2004
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 56 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program