Reviewed, UniProtKB/Swiss-Prot Q8A3X5 (SYR_BACTN)

Names and origin

Protein names

Recommended name:
    Arginyl-tRNA synthetase
    EC=6.1.1.19
Alternative name(s):
    Arginine--tRNA ligase
      Short name=ArgRS

Gene names

Name:	argS
Ordered Locus Names:	BT_2829

Organism

Bacteroides thetaiotaomicron [Complete proteome] [HAMAP]

Taxonomic identifier

818 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	597 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00123
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 597	597	Arginyl-tRNA synthetase HAMAP MF_00123		PRO_0000151531
Regions
	Motif	125 – 135	11	"HIGH" region HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	Q8A3X5-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 14983726E8F617B0	FASTA	597	66,954
	10 20 30 40 50 60 MKIEDKLVAS VINGLKALYG QEVPEKMVQL QKTKKEFEGH LTLVVFPFLK MSRKGPEQTA 70 80 90 100 110 120 QEIGEYLKAN EPAVAAFNVI KGFLNLTIAS ATWIELLNEI QSDEEYGLVK ATETSPLVMI 130 140 150 160 170 180 EYSSPNTNKP LHLGHVRNNL LGNALANIVA ANGNRVVKTN IVNDRGIHIC KSMLAWKKYG 190 200 210 220 230 240 NGETPESTGK KGDHLVGDYY VSFDKHYKAE LAELMEKGMT KEEAEAASPL MQEAREMLVK 250 260 270 280 290 300 WEAGDPEVRA LWEMMNNWVY AGFDETYRKM GVGFDKIYYE SNTYLEGKEK VMEGLEKGFF 310 320 330 340 350 360 FKKEDGSVWV DLTAEGLDHK LLLRGDGTSV YMTQDIGTAK LRFADYPIDK MIYVVGNEQN 370 380 390 400 410 420 YHFQVLSILL DKLGFEWGKG LVHFSYGMVE LPEGKMKSRE GTVVDADDLM EEMVSTAKET 430 440 450 460 470 480 SQELGKLDGL TQEEADDIAR IVGLGALKYF ILKVDARKNM TFNPKESIDF NGNTGPFIQY 490 500 510 520 530 540 TYARIQSVLR KAAESGIVIP EQIPAGIELS EKEEGLIQLV ADFAAVVKQA GEDYSPSIIA 550 560 570 580 590 NYTYDLVKEY NQFYHDFSIL REENEAVKVF RIALSANVAK VVRLGMGLLG IEVPSRM

References

[1]

"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis." Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I. Science 299:2074-2076(2003) [PubMed: 12663928] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE015928 Genomic DNA. Translation: AAO77935.1.
RefSeq	NP_811741.1.
3D structure databases
HSSP	HSSP built from PDB template 1IQ0 based on UniProtKB Q93RP5.
ModBase	Search...
Genome annotation databases
GeneID	1076299.
GenomeReviews	Gene locus BT_2829 in contig AE015928_GR.
KEGG	bth:BT_2829.
NMPDR	fig|226186.1.peg.2828.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8A3X5.
OMA	YNDDLQP.
Enzyme and pathway databases
BioCyc	BTHE226186:BT_2829-MON.
BRENDA	6.1.1.19. 21018.
Family and domain databases
HAMAP	MF_00123. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ic. IPR015945. Arg-tRNA-synth_Ic_core. IPR005148. Arg-tRNA-synth_Ic_N. IPR008909. DALR_anticod_bd. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_BACTN

Accession

Primary (citable) accession number: Q8A3X5

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 14, 2003
Last sequence update:	June 1, 2003
Last modified:	November 3, 2009
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)