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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei48NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Enzyme and pathway databases

BioCyciBTHE:G13PU-8179-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:BT_3213
OrganismiBacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Taxonomic identifieri226186 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
Proteomesi
  • UP000001414 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001217931 – 240tRNA pseudouridine synthase BAdd BLAST240

Proteomic databases

PaxDbiQ8A2U2

Interactioni

Protein-protein interaction databases

STRINGi226186.BT_3213

Structurei

3D structure databases

ProteinModelPortaliQ8A2U2
SMRiQ8A2U2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D0T Bacteria
COG0130 LUCA
HOGENOMiHOG000231223
InParanoidiQ8A2U2
KOiK03177
OMAiVDCSKGT
OrthoDBiPOG091H02G9

Family and domain databases

HAMAPiMF_01080 TruB_bact, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR002501 PsdUridine_synth_N
IPR014780 tRNA_psdUridine_synth_TruB
IPR032819 TruB_C
PANTHERiPTHR13767 PTHR13767, 1 hit
PfamiView protein in Pfam
PF16198 TruB_C_2, 1 hit
PF01509 TruB_N, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00431 TruB, 1 hit

Sequencei

Sequence statusi: Complete.

Q8A2U2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNFKKGEVLF FNKPLGWTSF KVVGHVRYHI CRRIGVKKLK VGHAGTLDPL
60 70 80 90 100
ATGVMILCTG KATKRIEEFQ YHTKEYVATL RLGATTPSYD LEHEIDATYP
110 120 130 140 150
TGHITRELVE ETLTHFLGAI EQVPPAFSAC MVDGKRAYEL ARKGEEVELK
160 170 180 190 200
AKQLVIDEIE LLECRLDDPE PTIRIRVVCS KGTYIRALAR DIGEALQSGA
210 220 230 240
HLTELIRTRV GDVRLEDCLD PEHFKEWIDR QEIENDEDNN
Length:240
Mass (Da):27,290
Last modified:June 1, 2003 - v1
Checksum:i5FAF762E7C0A0AAE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015928 Genomic DNA Translation: AAO78319.1
RefSeqiNP_812125.1, NC_004663.1
WP_008762820.1, NC_004663.1

Genome annotation databases

EnsemblBacteriaiAAO78319; AAO78319; BT_3213
GeneIDi1075890
31619483
KEGGibth:BT_3213
PATRICifig|226186.12.peg.3276

Similar proteinsi

Entry informationi

Entry nameiTRUB_BACTN
AccessioniPrimary (citable) accession number: Q8A2U2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2003
Last sequence update: June 1, 2003
Last modified: March 28, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health