Q8A2B0 (ARGB_BACTN) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 69.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Acetylglutamate kinase EC=2.7.2.8 Alternative name(s): N-acetyl-L-glutamate 5-phosphotransferase NAG kinase Short name=AGK | ||||
| Gene names |
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| Organism | Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482) | ||||
| Taxonomic identifier | 226186 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides |
Protein attributes
| Sequence length | 257 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate. HAMAP MF_00082_B |
| Pathway | Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4. HAMAP MF_00082_B |
| Subcellular location | Cytoplasm By similarity HAMAP MF_00082_B. |
| Sequence similarities | Belongs to the acetylglutamate kinase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Arginine biosynthesis |
| Cellular component | Cytoplasm |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Kinase Transferase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | arginine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetylglutamate kinase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 257 | 257 | Acetylglutamate kinase HAMAP MF_00082_B | PRO_0000112588 | |||||
Regions | |||||||||
| Region | 41 – 42 | 2 | Substrate binding By similarity | ||||||
Sites | |||||||||
| Binding site | 63 | 1 | Substrate By similarity | ||||||
| Binding site | 158 | 1 | Substrate By similarity | ||||||
| Site | 9 | 1 | Transition state stabilizer By similarity | ||||||
| Site | 224 | 1 | Transition state stabilizer By similarity | ||||||
Sequences
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References
| [1] | "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis." Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I. Science 299:2074-2076(2003) [PubMed: 12663928] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AE015928 Genomic DNA. Translation: AAO78501.1. |
| RefSeq | NP_812307.1. NC_004663.1. |
3D structure databases | |
| ProteinModelPortal | Q8A2B0. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 1076301. |
| GenomeReviews | Gene locus BT_3395 in contig AE015928_GR. |
| KEGG | bth:BT_3395. |
| NMPDR | fig|226186.1.peg.3394. |
| PATRIC | 21061803. VBIBacThe70966_3463. |
Phylogenomic databases | |
| HOGENOM | HBG497643. |
| OMA | GGCLVDD. |
| PhylomeDB | Q8A2B0. |
| ProtClustDB | CLSK913611. |
Enzyme and pathway databases | |
| BioCyc | BTHE226186:BT_3395-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00082_B. ArgB_B. [Tree] |
| InterPro | IPR004662. AcgluKinase. IPR001048. Asp/Glu/Uridylate_kinase. [Graphical view] |
| Gene3D | G3DSA:3.40.1160.10. Aa_kinase. 1 hit. |
| KO | K00930. |
| Pfam | PF00696. AA_kinase. 1 hit. [Graphical view] |
| PIRSF | PIRSF000728. NAGK. 1 hit. |
| SUPFAM | SSF53633. Aa_kinase. 1 hit. |
| TIGRFAMs | TIGR00761. ArgB. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | ARGB_BACTN | ||||||||
| Accession | Primary (citable) accession number: Q8A2B0 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with