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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei143GTPUniRule annotation1
Binding sitei147GTPUniRule annotation1
Binding sitei190GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi24 – 28GTPUniRule annotation5
Nucleotide bindingi112 – 114GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, SeptationUniRule annotation

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:BT_3444Imported
OrganismiBacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)Imported
Taxonomic identifieri226186 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
Proteomesi
  • UP000001414 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

PTM / Processingi

Proteomic databases

PaxDbiQ8A262.

Interactioni

Protein-protein interaction databases

STRINGi226186.BT_3444.

Structurei

3D structure databases

ProteinModelPortaliQ8A262.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 208TubulinInterPro annotationAdd BLAST193
Domaini210 – 329Tubulin_CInterPro annotationAdd BLAST120

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili334 – 357Sequence analysisAdd BLAST24

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105CDK. Bacteria.
COG0206. LUCA.
HOGENOMiHOG000049094.
InParanoidiQ8A262.
KOiK03531.
OMAiMSIFARM.
OrthoDBiPOG091H02KK.

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiIPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamiPF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
[Graphical view]
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiPS01135. FTSZ_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8A262-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDEIVQFDFP TDSPKIIKVI GVGGGGGNAV NHMYREGIHD VTFVLCNTDN
60 70 80 90 100
QALAESPVPV KLQLGRSITQ GLGAGNRPER ARDAAEESID DIKEQLNDGT
110 120 130 140 150
KMVFITAGMG GGTGTGAAPV IARIAKEMDI LTVGIVTIPF IFEGEKKIIQ
160 170 180 190 200
ALDGVERIAQ HVDALLVINN ERLREIYADL TFMNAFGKAD DTLSIAAKSI
210 220 230 240 250
AEIITMRGTV NLDFADVKTI LKDGGVAIMS TGFGEGENRV TKAIDDALHS
260 270 280 290 300
PLLNNNDIFN AKKVMLNVSF CPTSELMMEE MNEIHEFMSK FREGVEVIWG
310 320 330 340 350
VAVDNSLDTK VKITVLATGF GVEDVPGMDT LHEARSQEEE ERQLQLEEEK
360 370 380 390 400
EKNKERIRKA YGESAGIGKK SLRSRRHIYI FNTEDLDNDD IIAMIEESPT
410 420 430
YTRDKTKLLK IKTKAALEEE VAMEEATDND GVITF
Length:435
Mass (Da):47,799
Last modified:June 1, 2003 - v1
Checksum:i248A99CA0DB7B7BC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015928 Genomic DNA. Translation: AAO78550.1.
RefSeqiNP_812356.1. NC_004663.1.
WP_008763706.1. NC_004663.1.

Genome annotation databases

EnsemblBacteriaiAAO78550; AAO78550; BT_3444.
GeneIDi1073669.
KEGGibth:BT_3444.
PATRICi21061895. VBIBacThe70966_3508.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015928 Genomic DNA. Translation: AAO78550.1.
RefSeqiNP_812356.1. NC_004663.1.
WP_008763706.1. NC_004663.1.

3D structure databases

ProteinModelPortaliQ8A262.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi226186.BT_3444.

Proteomic databases

PaxDbiQ8A262.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO78550; AAO78550; BT_3444.
GeneIDi1073669.
KEGGibth:BT_3444.
PATRICi21061895. VBIBacThe70966_3508.

Phylogenomic databases

eggNOGiENOG4105CDK. Bacteria.
COG0206. LUCA.
HOGENOMiHOG000049094.
InParanoidiQ8A262.
KOiK03531.
OMAiMSIFARM.
OrthoDBiPOG091H02KK.

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiIPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PfamiPF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
[Graphical view]
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiPS01135. FTSZ_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8A262_BACTN
AccessioniPrimary (citable) accession number: Q8A262
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: November 30, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.