ID   ACKA_BACTN              Reviewed;         399 AA.
AC   Q8A1G8;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   16-JUN-2009, entry version 45.
DE   RecName: Full=Acetate kinase;
DE            EC=2.7.2.1;
DE   AltName: Full=Acetokinase;
GN   Name=ackA; OrderedLocusNames=BT_3693;
OS   Bacteroides thetaiotaomicron.
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=818;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482;
RX   MEDLINE=22550858; PubMed=12663928; DOI=10.1126/science.1080029;
RA   Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K.,
RA   Chiang H.C., Hooper L.V., Gordon J.I.;
RT   "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis.";
RL   Science 299:2074-2076(2003).
CC   -!- CATALYTIC ACTIVITY: ATP + acetate = ADP + acetyl phosphate.
CC   -!- CATALYTIC ACTIVITY: ATP + propanoate = ADP + propanoyl phosphate.
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; acetyl-CoA
CC       biosynthesis; acetyl-CoA from acetate: step 1/2.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the acetokinase family.
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DR   EMBL; AE015928; AAO78798.1; -; Genomic_DNA.
DR   RefSeq; NP_812604.1; -.
DR   HSSP; P38502; 1G99.
DR   GeneID; 1076294; -.
DR   GenomeReviews; AE015928_GR; BT_3693.
DR   KEGG; bth:BT_3693; -.
DR   NMPDR; fig|226186.1.peg.3691; -.
DR   HOGENOM; Q8A1G8; -.
DR   OMA; Q8A1G8; SSDFRDV.
DR   BioCyc; BTHE226186:BT_3693-MON; -.
DR   BRENDA; 2.7.2.1; 21018.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008776; F:acetate kinase activity; IEA:HAMAP.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006082; P:organic acid metabolic process; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:HAMAP.
DR   HAMAP; MF_00020; -; 1.
DR   InterPro; IPR000890; Acetate_kin.
DR   InterPro; IPR004372; AckA.
DR   PANTHER; PTHR21060; Acetate_kin; 1.
DR   PANTHER; PTHR21060:SF11; AckA; 1.
DR   Pfam; PF00871; Acetate_kinase; 1.
DR   PIRSF; PIRSF000722; Acetate_prop_kin; 1.
DR   PRINTS; PR00471; ACETATEKNASE.
DR   TIGRFAMs; TIGR00016; ackA; 1.
DR   PROSITE; PS01075; ACETATE_KINASE_1; 1.
DR   PROSITE; PS01076; ACETATE_KINASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding;
KW   Transferase.
FT   CHAIN         1    399       Acetate kinase.
FT                                /FTId=PRO_0000107535.
SQ   SEQUENCE   399 AA;  43340 MW;  9161287FEC871298 CRC64;
     MKILVLNCGS SSIKYKLFDM TTKEVIAQGG IEKIGLKGSF LKLTLPNGEK KVLEKDIPEH
     TIGVEFILNT LISPEYGAIK SLDEINAVGH RMVHGGERFS ESVLLNKEVL EAFAACNDLA
     PLHNPANLKG VNAVSAILPN IPQVGVFDTA FHQTMPDYAY MYAIPYEMYE KYGVRRYGFH
     GTSHRYVSKR VCEFLGVNPV GQKIITCHIG NGGSIAAIKD GKCIDTTMGL TPLEGLMMGT
     RSGDIDAGAV TFIMEKEGLN TTGISNLLNK KSGVLGISGV SSDMRELLAA CANGNERAIL
     AEKMYYYRIK KYIGAYAAAL GGVDIILFTG GVGENQFECR ESVCKDMEFM GIKLDNNVNA
     KVRGEEAIIS TADSKVKVVV IPTDEELLIA SDTMDILKK
//