Reviewed, UniProtKB/Swiss-Prot Q8A1G8 (ACKA_BACTN)

Names and origin

Protein names

Recommended name:
    Acetate kinase
    EC=2.7.2.1
Alternative name(s):
    Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	BT_3693

Organism

Bacteroides thetaiotaomicron [Complete proteome] [HAMAP]

Taxonomic identifier

818 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	399 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 399	399	Acetate kinase HAMAP MF_00020		PRO_0000107535

Sequences

	Sequence		Length	Mass (Da)
	Q8A1G8-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 9161287FEC871298	FASTA	399	43,340
	10 20 30 40 50 60 MKILVLNCGS SSIKYKLFDM TTKEVIAQGG IEKIGLKGSF LKLTLPNGEK KVLEKDIPEH 70 80 90 100 110 120 TIGVEFILNT LISPEYGAIK SLDEINAVGH RMVHGGERFS ESVLLNKEVL EAFAACNDLA 130 140 150 160 170 180 PLHNPANLKG VNAVSAILPN IPQVGVFDTA FHQTMPDYAY MYAIPYEMYE KYGVRRYGFH 190 200 210 220 230 240 GTSHRYVSKR VCEFLGVNPV GQKIITCHIG NGGSIAAIKD GKCIDTTMGL TPLEGLMMGT 250 260 270 280 290 300 RSGDIDAGAV TFIMEKEGLN TTGISNLLNK KSGVLGISGV SSDMRELLAA CANGNERAIL 310 320 330 340 350 360 AEKMYYYRIK KYIGAYAAAL GGVDIILFTG GVGENQFECR ESVCKDMEFM GIKLDNNVNA 370 380 390 KVRGEEAIIS TADSKVKVVV IPTDEELLIA SDTMDILKK

References

[1]

"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis." Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I. Science 299:2074-2076(2003) [PubMed: 12663928] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE015928 Genomic DNA. Translation: AAO78798.1.
RefSeq	NP_812604.1.
3D structure databases
HSSP	HSSP built from PDB template 1G99 based on UniProtKB P38502.
ModBase	Search...
Genome annotation databases
GeneID	1076294.
GenomeReviews	Gene locus BT_3693 in contig AE015928_GR.
KEGG	bth:BT_3693.
NMPDR	fig|226186.1.peg.3691.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8A1G8.
OMA	Q8A1G8. SSDFRDV.
Enzyme and pathway databases
BioCyc	BTHE226186:BT_3693-MON.
BRENDA	2.7.2.1. 21018.
Family and domain databases
HAMAP	MF_00020. [Tree]
InterPro	IPR000890. Acetate_kin. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_BACTN

Accession

Primary (citable) accession number: Q8A1G8

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 1, 2005
Last sequence update:	June 1, 2003
Last modified:	June 16, 2009
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)