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Q8A1G8 (ACKA_BACTN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:BT_3693
OrganismBacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Taxonomic identifier226186 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length399 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 399399Acetate kinase HAMAP MF_00020
PRO_0000107535

Sequences

Sequence LengthMass (Da)Tools
Q8A1G8 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 9161287FEC871298

FASTA39943,340
        10         20         30         40         50         60 
MKILVLNCGS SSIKYKLFDM TTKEVIAQGG IEKIGLKGSF LKLTLPNGEK KVLEKDIPEH 

        70         80         90        100        110        120 
TIGVEFILNT LISPEYGAIK SLDEINAVGH RMVHGGERFS ESVLLNKEVL EAFAACNDLA 

       130        140        150        160        170        180 
PLHNPANLKG VNAVSAILPN IPQVGVFDTA FHQTMPDYAY MYAIPYEMYE KYGVRRYGFH 

       190        200        210        220        230        240 
GTSHRYVSKR VCEFLGVNPV GQKIITCHIG NGGSIAAIKD GKCIDTTMGL TPLEGLMMGT 

       250        260        270        280        290        300 
RSGDIDAGAV TFIMEKEGLN TTGISNLLNK KSGVLGISGV SSDMRELLAA CANGNERAIL 

       310        320        330        340        350        360 
AEKMYYYRIK KYIGAYAAAL GGVDIILFTG GVGENQFECR ESVCKDMEFM GIKLDNNVNA 

       370        380        390 
KVRGEEAIIS TADSKVKVVV IPTDEELLIA SDTMDILKK

« Hide

References

[1]"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis."
Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I.
Science 299:2074-2076(2003) [PubMed: 12663928] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE015928 Genomic DNA. Translation: AAO78798.1.
RefSeqNP_812604.1. NC_004663.1.

3D structure databases

ProteinModelPortalQ8A1G8.
SMRQ8A1G8. Positions 1-399.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1076294.
GenomeReviewsGene locus BT_3693 in contig AE015928_GR.
KEGGbth:BT_3693.
NMPDRfig|226186.1.peg.3691.
PATRIC21062387. VBIBacThe70966_3753.

Phylogenomic databases

HOGENOMHBG285863.
OMALIDMTNE.
PhylomeDBQ8A1G8.
ProtClustDBPRK00180.

Enzyme and pathway databases

BioCycBTHE226186:BT_3693-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_BACTN
AccessionPrimary (citable) accession number: Q8A1G8
Entry history
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: June 1, 2003
Last modified: January 25, 2012
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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