Reviewed,
UniProtKB/Swiss-Prot Q8A0L8 (SURE_BACTN)
Last modified
June 16, 2009.
Version 45.
History...
Clusters with 100%,
90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: 5'-nucleotidase surE EC=3.1.3.5 Alternative name(s): Nucleoside 5'-monophosphate phosphohydrolase | ||||
| Gene names |
| ||||
| Organism | Bacteroides thetaiotaomicron [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 818 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides |
Protein attributes
| Sequence length | 259 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. |
| Catalytic activity | A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060 |
| Cofactor | Binds 1 divalent metal cation per subunit By similarity. |
| Subcellular location | Cytoplasm Potential. |
| Sequence similarities | Belongs to the surE nucleotidase family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm |
| Ligand | Metal-binding Nucleotide-binding |
| Molecular function | Hydrolase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | 5'-nucleotidase activity Inferred from electronic annotation. Source: HAMAP metal ion bindingInferred from electronic annotation. Source: HAMAP nucleotide bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 259 | 259 | 5'-nucleotidase surE HAMAP MF_00060 | PRO_0000111789 | |||||
Sites | |||||||||
| Metal binding | 13 | 1 | Divalent metal cation By similarity | ||||||
| Metal binding | 14 | 1 | Divalent metal cation By similarity | ||||||
| Metal binding | 44 | 1 | Divalent metal cation By similarity | ||||||
| Metal binding | 100 | 1 | Divalent metal cation By similarity | ||||||
Sequences
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References
| [1] | "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis." Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I. Science 299:2074-2076(2003) [PubMed: 12663928] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482. |
Cross-references
Sequence databases | |
|---|---|
| AE015928 Genomic DNA. Translation: AAO79108.1. | |
| RefSeq | NP_812914.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1J9L based on UniProtKB P96112. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1074660. |
| GenomeReviews | Gene locus BT_4003 in contig AE015928_GR. |
| KEGG | bth:BT_4003. |
| NMPDR | fig|226186.1.peg.4001. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | Q8A0L8. |
| OMA | Q8A0L8. SINIPIK. |
Enzyme and pathway databases | |
| BioCyc | BTHE226186:BT_4003-MON. |
| BRENDA | 3.1.3.5. 21018. |
Family and domain databases | |
| HAMAP | MF_00060. [Tree] |
| InterPro | IPR002828. SurE-like_Pase/nucleotidase. [Graphical view] |
| Gene3D | G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit. |
| Pfam | PF01975. SurE. 1 hit. [Graphical view] |
| ProDom | PD005378. SurE. 1 hit. [Graphical view] [Entries sharing at least one domain] |
| TIGRFAMs | TIGR00087. surE. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | SURE_BACTN | ||||||||
| Accession | Primary (citable) accession number: Q8A0L8 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||

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