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Protein

Beta-galactosidase

Gene

BT_4050

Organism
Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.SAAS annotation

GO - Molecular functioni

  1. beta-galactosidase activity Source: UniProtKB-EC
  2. carbohydrate binding Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseSAAS annotation, Hydrolase

Enzyme and pathway databases

BioCyciBTHE226186:GJXV-4128-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidaseSAAS annotation (EC:3.2.1.23SAAS annotation)
Gene namesi
Ordered Locus Names:BT_4050Imported
OrganismiBacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)Imported
Taxonomic identifieri226186 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
ProteomesiUP000001414: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. beta-galactosidase complex Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi226186.BT_4050.

Structurei

3D structure databases

ProteinModelPortaliQ8A0H1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000252444.
InParanoidiQ8A0H1.
KOiK01190.
OMAiFHISEYA.
OrthoDBiEOG6XWV0T.

Family and domain databases

Gene3Di2.60.120.260. 2 hits.
2.60.40.320. 2 hits.
2.70.98.10. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR004199. B-gal_small/dom_5.
IPR004867. CHB_HEX_C_dom.
IPR000421. Coagulation_fac_5/8-C_type_dom.
IPR011013. Gal_mutarotase_SF_dom.
IPR008979. Galactose-bd-like.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02929. Bgal_small_N. 1 hit.
PF03174. CHB_HEX_C. 1 hit.
PF00754. F5_F8_type_C. 1 hit.
PF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view]
PRINTSiPR00132. GLHYDRLASE2.
SMARTiSM01038. Bgal_small_N. 1 hit.
SM00231. FA58C. 1 hit.
[Graphical view]
SUPFAMiSSF49303. SSF49303. 2 hits.
SSF49785. SSF49785. 2 hits.
SSF51445. SSF51445. 1 hit.
SSF74650. SSF74650. 2 hits.
PROSITEiPS50022. FA58C_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8A0H1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKTLLTGLL CCSLSIQSFA DQPLEGFTYG SVNAPTGKEW ESPENLALNK
60 70 80 90 100
EQPHAYFFPF QHLDNARKVL PENSKYWQSL DGDWKFHWAP DPDSRPKDFY
110 120 130 140 150
QTEYDVSSWD AIPVPSSWNI YGIQKDGSQK YGTPIYVNQP VIFQHSVKVD
160 170 180 190 200
DWRGGVMRTP PANWTTYKDR NEVGSFRRDF EIPQDWDGRE VFISFDGVDS
210 220 230 240 250
FFYLWINGQY VGFSKNSRNT ANFNITPYLQ KGKNTVAAEV YRSSDGSFLE
260 270 280 290 300
AQDMFRLPGI FRTVALYSVP KVHFRDLVAT PDLDATYTDG SLTVNAEIRN
310 320 330 340 350
LDKKAIKDYK VYYSLYANKL YSDENTLVDG FLSPVIDKIA PNETGSVQTV
360 370 380 390 400
LKVKAPNKWS AEFPYRYTLV AELKDKKNRT VEMVSTIVGF RKVEIKDTPA
410 420 430 440 450
SEDEFGLAGR YYYVNGKTVK LKGVNRHESN PGVGHAITRE MMEKEIMLMK
460 470 480 490 500
RANINHVRNS HYPDDPYWYF LCNKYGIYLE DEANIESHEY YYGAASLSHP
510 520 530 540 550
VEWKNAHVAR VMEMVRANVN NPSIVIWSLG NEAGPGKNFV AAYDALKKFD
560 570 580 590 600
TSRPVQYERN NDIVDMGSNQ YPSIGWVRGA VQGKYDIKYP FHISEYAHSM
610 620 630 640 650
GNACGNLIDY WEAMESTNFF CGGAIWDWVD QSMYNYDPKT GVRYLAYGGD
660 670 680 690 700
FGDTPNDGQF VMNGIVFGDL EPKPQYYEVK KVYQHIGVKA IDTEKGVFEI
710 720 730 740 750
FNKYYFKNLA EDYQLVYSLY EDGKPIMTGK PMDINIAPRQ RAQITLPYDH
760 770 780 790 800
ASLKKDAEYF MKLQFILKDQ RPWAAKGFPM AEEQILIKEA TDRPSISEVT
810 820 830 840 850
AGAAKLDGFV LDKDTKRILI KGADFEAIFD PQTGSIYSLK YGNETVIADG
860 870 880 890 900
NGPKLDALRA FTNNDNWFYA PWFEHGLHNL IHKATEYKVL NKGNGTLVLS
910 920 930 940 950
FTVESQAPNA ARIKGGTSSG KNSIEELTDR KFGSNDFKFV TNQIWTVYPD
960 970 980 990 1000
GSIELQSSIT SNRSSLVLPR LGYVMKVPQQ YSNFTYYGRG PIDNYADRKS
1010 1020 1030 1040 1050
GQFIEQYTNS VAGEFVNFPK PQDMGNHEDV RWCALTNQAG NGAVFVATDR
1060 1070 1080 1090 1100
LSASALQYSA LDLILASHPY QLPKAGDTYL HLDCAVTGLG GNSCGQGAPL
1110 1120 1130 1140 1150
VHDRVFANQH SMGFIIRPAD KELSVVANVA PAGDLPLSIT RTPAGMVELT
1160 1170 1180 1190 1200
SAKKDAVICY SIDGSKKVQE YTEPVPMRNG GTIKAWYKDS KDISSTMKFE
1210 1220 1230 1240 1250
KIESIQTQVV YASSQESGEG DASHLTDGDP NTIWHTMYSV TVAKYPHWVD
1260 1270 1280 1290 1300
LDAGEVKEIK GFTYLPRQNG GNGNIKDYSI QVSMDGKEWG EPVNKGTFAR
1310 1320 1330 1340
DSKEKRVLFD KPVKARYIRF TALSEQNGQD FASGAEITIL AN
Length:1,342
Mass (Da):151,288
Last modified:June 1, 2003 - v1
Checksum:i1F4BC3289C137A1B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015928 Genomic DNA. Translation: AAO79155.1.
RefSeqiNP_812961.1. NC_004663.1.
WP_011109085.1. NC_004663.1.

Genome annotation databases

EnsemblBacteriaiAAO79155; AAO79155; BT_4050.
GeneIDi1073210.
KEGGibth:BT_4050.
PATRICi21063130. VBIBacThe70966_4112.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015928 Genomic DNA. Translation: AAO79155.1.
RefSeqiNP_812961.1. NC_004663.1.
WP_011109085.1. NC_004663.1.

3D structure databases

ProteinModelPortaliQ8A0H1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi226186.BT_4050.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAO79155; AAO79155; BT_4050.
GeneIDi1073210.
KEGGibth:BT_4050.
PATRICi21063130. VBIBacThe70966_4112.

Phylogenomic databases

HOGENOMiHOG000252444.
InParanoidiQ8A0H1.
KOiK01190.
OMAiFHISEYA.
OrthoDBiEOG6XWV0T.

Enzyme and pathway databases

BioCyciBTHE226186:GJXV-4128-MONOMER.

Family and domain databases

Gene3Di2.60.120.260. 2 hits.
2.60.40.320. 2 hits.
2.70.98.10. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR004199. B-gal_small/dom_5.
IPR004867. CHB_HEX_C_dom.
IPR000421. Coagulation_fac_5/8-C_type_dom.
IPR011013. Gal_mutarotase_SF_dom.
IPR008979. Galactose-bd-like.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02929. Bgal_small_N. 1 hit.
PF03174. CHB_HEX_C. 1 hit.
PF00754. F5_F8_type_C. 1 hit.
PF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view]
PRINTSiPR00132. GLHYDRLASE2.
SMARTiSM01038. Bgal_small_N. 1 hit.
SM00231. FA58C. 1 hit.
[Graphical view]
SUPFAMiSSF49303. SSF49303. 2 hits.
SSF49785. SSF49785. 2 hits.
SSF51445. SSF51445. 1 hit.
SSF74650. SSF74650. 2 hits.
PROSITEiPS50022. FA58C_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis."
    Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I.
    Science 299:2074-2076(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: VPI-5482Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482Imported.

Entry informationi

Entry nameiQ8A0H1_BACTN
AccessioniPrimary (citable) accession number: Q8A0H1
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: March 4, 2015
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.