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Protein

Beta-galactosidase

Gene

BT_4050

Organism
Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseSAAS annotation, Hydrolase

Enzyme and pathway databases

BioCyciBTHE:G13PU-9030-MONOMER

Protein family/group databases

CAZyiGH2 Glycoside Hydrolase Family 2

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-galactosidaseSAAS annotation (EC:3.2.1.23SAAS annotation)
Gene namesi
Ordered Locus Names:BT_4050Imported
OrganismiBacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)Imported
Taxonomic identifieri226186 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides
Proteomesi
  • UP000001414 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500430282821 – 1342Beta-galactosidaseSequence analysisAdd BLAST1322

Proteomic databases

PaxDbiQ8A0H1
PRIDEiQ8A0H1

Interactioni

Protein-protein interaction databases

STRINGi226186.BT_4050

Structurei

3D structure databases

ProteinModelPortaliQ8A0H1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1190 – 1342F5/8 type CInterPro annotationAdd BLAST153

Sequence similaritiesi

Belongs to the glycosyl hydrolase 2 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4105CNT Bacteria
COG3250 LUCA
HOGENOMiHOG000252444
InParanoidiQ8A0H1
KOiK01190
OMAiDSFFYLW
OrthoDBiPOG091H07QB

Family and domain databases

Gene3Di2.60.120.260, 2 hits
2.60.40.10, 2 hits
2.70.98.10, 1 hit
InterProiView protein in InterPro
IPR004199 B-gal_small/dom_5
IPR036156 Beta-gal/glucu_dom_sf
IPR000421 FA58C
IPR011013 Gal_mutarotase_sf_dom
IPR008979 Galactose-bd-like_sf
IPR014718 GH-type_carb-bd
IPR006101 Glyco_hydro_2
IPR006103 Glyco_hydro_2_cat
IPR006102 Glyco_hydro_2_Ig-like
IPR006104 Glyco_hydro_2_N
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
IPR032312 LacZ_4
PfamiView protein in Pfam
PF02929 Bgal_small_N, 1 hit
PF16353 DUF4981, 1 hit
PF00754 F5_F8_type_C, 1 hit
PF00703 Glyco_hydro_2, 1 hit
PF02836 Glyco_hydro_2_C, 1 hit
PF02837 Glyco_hydro_2_N, 1 hit
PRINTSiPR00132 GLHYDRLASE2
SMARTiView protein in SMART
SM01038 Bgal_small_N, 1 hit
SUPFAMiSSF49303 SSF49303, 2 hits
SSF49785 SSF49785, 2 hits
SSF51445 SSF51445, 1 hit
SSF74650 SSF74650, 2 hits
PROSITEiView protein in PROSITE
PS50022 FA58C_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q8A0H1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKTLLTGLL CCSLSIQSFA DQPLEGFTYG SVNAPTGKEW ESPENLALNK
60 70 80 90 100
EQPHAYFFPF QHLDNARKVL PENSKYWQSL DGDWKFHWAP DPDSRPKDFY
110 120 130 140 150
QTEYDVSSWD AIPVPSSWNI YGIQKDGSQK YGTPIYVNQP VIFQHSVKVD
160 170 180 190 200
DWRGGVMRTP PANWTTYKDR NEVGSFRRDF EIPQDWDGRE VFISFDGVDS
210 220 230 240 250
FFYLWINGQY VGFSKNSRNT ANFNITPYLQ KGKNTVAAEV YRSSDGSFLE
260 270 280 290 300
AQDMFRLPGI FRTVALYSVP KVHFRDLVAT PDLDATYTDG SLTVNAEIRN
310 320 330 340 350
LDKKAIKDYK VYYSLYANKL YSDENTLVDG FLSPVIDKIA PNETGSVQTV
360 370 380 390 400
LKVKAPNKWS AEFPYRYTLV AELKDKKNRT VEMVSTIVGF RKVEIKDTPA
410 420 430 440 450
SEDEFGLAGR YYYVNGKTVK LKGVNRHESN PGVGHAITRE MMEKEIMLMK
460 470 480 490 500
RANINHVRNS HYPDDPYWYF LCNKYGIYLE DEANIESHEY YYGAASLSHP
510 520 530 540 550
VEWKNAHVAR VMEMVRANVN NPSIVIWSLG NEAGPGKNFV AAYDALKKFD
560 570 580 590 600
TSRPVQYERN NDIVDMGSNQ YPSIGWVRGA VQGKYDIKYP FHISEYAHSM
610 620 630 640 650
GNACGNLIDY WEAMESTNFF CGGAIWDWVD QSMYNYDPKT GVRYLAYGGD
660 670 680 690 700
FGDTPNDGQF VMNGIVFGDL EPKPQYYEVK KVYQHIGVKA IDTEKGVFEI
710 720 730 740 750
FNKYYFKNLA EDYQLVYSLY EDGKPIMTGK PMDINIAPRQ RAQITLPYDH
760 770 780 790 800
ASLKKDAEYF MKLQFILKDQ RPWAAKGFPM AEEQILIKEA TDRPSISEVT
810 820 830 840 850
AGAAKLDGFV LDKDTKRILI KGADFEAIFD PQTGSIYSLK YGNETVIADG
860 870 880 890 900
NGPKLDALRA FTNNDNWFYA PWFEHGLHNL IHKATEYKVL NKGNGTLVLS
910 920 930 940 950
FTVESQAPNA ARIKGGTSSG KNSIEELTDR KFGSNDFKFV TNQIWTVYPD
960 970 980 990 1000
GSIELQSSIT SNRSSLVLPR LGYVMKVPQQ YSNFTYYGRG PIDNYADRKS
1010 1020 1030 1040 1050
GQFIEQYTNS VAGEFVNFPK PQDMGNHEDV RWCALTNQAG NGAVFVATDR
1060 1070 1080 1090 1100
LSASALQYSA LDLILASHPY QLPKAGDTYL HLDCAVTGLG GNSCGQGAPL
1110 1120 1130 1140 1150
VHDRVFANQH SMGFIIRPAD KELSVVANVA PAGDLPLSIT RTPAGMVELT
1160 1170 1180 1190 1200
SAKKDAVICY SIDGSKKVQE YTEPVPMRNG GTIKAWYKDS KDISSTMKFE
1210 1220 1230 1240 1250
KIESIQTQVV YASSQESGEG DASHLTDGDP NTIWHTMYSV TVAKYPHWVD
1260 1270 1280 1290 1300
LDAGEVKEIK GFTYLPRQNG GNGNIKDYSI QVSMDGKEWG EPVNKGTFAR
1310 1320 1330 1340
DSKEKRVLFD KPVKARYIRF TALSEQNGQD FASGAEITIL AN
Length:1,342
Mass (Da):151,288
Last modified:June 1, 2003 - v1
Checksum:i1F4BC3289C137A1B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE015928 Genomic DNA Translation: AAO79155.1
RefSeqiNP_812961.1, NC_004663.1
WP_011109085.1, NC_004663.1

Genome annotation databases

EnsemblBacteriaiAAO79155; AAO79155; BT_4050
GeneIDi1073210
KEGGibth:BT_4050
PATRICifig|226186.12.peg.4112

Similar proteinsi

Entry informationi

Entry nameiQ8A0H1_BACTN
AccessioniPrimary (citable) accession number: Q8A0H1
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health