Phosphohydrolase - Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

Preferred order of sections

Names and origin

Protein names

Submitted name:
Phosphohydrolase EMBL AAO79313.1

Gene names

Ordered Locus Names:

BT_4208

Organism

Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482)

Taxonomic identifier

226186 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	409 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	Nucleotide-binding PDB 2Q14
Molecular function	Hydrolase EMBL AAO79313.1
Technical term	3D-structure PDB 2Q14 Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	metal ion binding Inferred from electronic annotation. Source: InterPro nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Regions

Nucleotide binding

225 – 226

2

ADP PDB 2Q14

Sites

Binding site

7

1

ADP; via carbonyl oxygen PDB 2Q14

Binding site

24

1

ADP PDB 2Q14

Binding site

33

1

ADP PDB 2Q14

Binding site

46

1

ADP; via carbonyl oxygen PDB 2Q14

Binding site

202

1

ADP PDB 2Q14

Binding site

313

1

ADP PDB 2Q14

Sequences

Sequence

Length

Mass (Da)

Tools

Q8A013 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: DBCBC9DB373009B3
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FASTA

409

46,947

        10         20         30         40         50         60 
MPYERKIIND PVFGFINIPK GLLYDIVRHP LLQRLTRIKQ VGLSSVVYPG AQHTRFQHSL 

        70         80         90        100        110        120 
GAFYLMSEAI TQLTSKGNFI FDSEAEAVQA AILLHDIGHG PFSHVLEDTI VQGVSHEEIS 

       130        140        150        160        170        180 
LMLMERMNKE MNGQLSLAIQ IFKDEYPKRF LHQLVSGQLD MDRLDYLRRD SFYTGVTEGN 

       190        200        210        220        230        240 
IGSARIIKML DVADDRLVIE SKGIYSIENF LTARRLMYWQ VYLHKTSVAY ERMLISTLLR 

       250        260        270        280        290        300 
AKELASQGVE LFASPALHFF LYNDINHTEF HNNPDCLENF IQLDDNDIWT ALKVWSNHPD 

       310        320        330        340        350        360 
KVLSTLSLGM INRNIFKVEN SAEPIGEDRI KELTLQISQQ LGITLSEANY FVSTPSIEKN 

       370        380        390        400 
MYDPADDSID IIYKDGTIKN IAEASDMLNI SLLSKKVKKY YLCYQRLHR

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis." Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I. Science 299:2074-2076(2003) [PubMed: 12663928] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.
[2]	"Crystal structure of Phosphohydrolase (BT4208) from Bacteroides thetaiotaomicron VPI-5482 at 2.20 A resolution." Joint Center for Structural Genomics (JCSG) Submitted (MAY-2007) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS) IN COMPLEX WITH ADP.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE015928 Genomic DNA. Translation: AAO79313.1.

RefSeq

NP_813119.1. NC_004663.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2Q14	X-ray	2.20	A/B/C/D/E/F/G/H	1-409	[»]

ProteinModelPortal

Q8A013.

SMR

Q8A013. Positions 1-406.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

1074725.

GenomeReviews

Gene locus BT_4208 in contig AE015928_GR.

KEGG

bth:BT_4208.

NMPDR

fig|226186.1.peg.4206.

PATRIC

21063456. VBIBacThe70966_4275.

Phylogenomic databases

HOGENOM

HBG335288.

OMA

VSRYQMY.

PhylomeDB

Q8A013.

ProtClustDB

CLSK823835.

Family and domain databases

InterPro

IPR023279. HD.
IPR003607. Metal-dep_PHydrolase_HD_dom.
IPR006674. Metal-dep_PHydrolase_HD_sub.
[Graphical view]

Gene3D

G3DSA:1.10.3210.10. HD. 1 hit.

KO

K06885.

Pfam

PF01966. HD. 1 hit.
[Graphical view]

SMART

SM00471. HDc. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q8A013_BACTN

Accession

Primary (citable) accession number: Q8A013

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)