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Q8A012 (PYRF_BACTN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Orotidine 5'-phosphate decarboxylase

EC=4.1.1.23
Alternative name(s):
OMP decarboxylase
Short name=OMPDCase
Short name=OMPdecase
Gene names
Name:pyrF
Ordered Locus Names:BT_4209
OrganismBacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482) [Reference proteome] [HAMAP]
Taxonomic identifier226186 [NCBI]
Taxonomic lineageBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides

Protein attributes

Sequence length274 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 274274Orotidine 5'-phosphate decarboxylase HAMAP-Rule MF_01215
PRO_1000138945

Sites

Active site961Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8A012 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: DB4A532D4C38A7BC

FASTA27430,880
        10         20         30         40         50         60 
MNKQQLFENI KRKKSFLCVG LDTDIKKIPE HLLKEEDPIF AFNKAIIDAT ADLCIAYKPN 

        70         80         90        100        110        120 
LAFYESMGVK GWIAFEKTVK YIKENYPDQF IIADAKRGDI GNTSAMYART FFEELEIDSV 

       130        140        150        160        170        180 
TVAPYMGEDS VTPFLTYEGK WVILLALTSN KGSHDFQLTE DANGERLFEK VLRKSQEWAN 

       190        200        210        220        230        240 
DERMMYVVGA TQGRAFEDIR KIVPNHFLLV PGVGAQGGSL EEVCKYGMNS TCGLIVNSSR 

       250        260        270 
GIIYVDKTEK FAEAARLAAQ EVQVQMAEQL KAIL 

« Hide

References

[1]"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis."
Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I.
Science 299:2074-2076(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE015928 Genomic DNA. Translation: AAO79314.1.
RefSeqNP_813120.1. NC_004663.1.

3D structure databases

ProteinModelPortalQ8A012.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING226186.BT_4209.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAO79314; AAO79314; BT_4209.
GeneID1073762.
KEGGbth:BT_4209.
PATRIC21063458. VBIBacThe70966_4276.

Phylogenomic databases

eggNOGCOG0284.
HOGENOMHOG000245747.
KOK01591.
OMAREGPWSR.
OrthoDBEOG6DZF33.

Enzyme and pathway databases

BioCycBTHE226186:GJXV-4287-MONOMER.
UniPathwayUPA00070; UER00120.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_01215. OMPdecase_type2.
InterProIPR013785. Aldolase_TIM.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
TIGRFAMsTIGR02127. pyrF_sub2. 1 hit.
ProtoNetSearch...

Entry information

Entry namePYRF_BACTN
AccessionPrimary (citable) accession number: Q8A012
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 1, 2003
Last modified: May 14, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways