Reviewed, UniProtKB/Swiss-Prot Q89ZF2 (DEOC_BACTN)

Names and origin

Protein names

Recommended name:
    Deoxyribose-phosphate aldolase
    EC=4.1.2.4
Alternative name(s):
    Phosphodeoxyriboaldolase
      Short name=Deoxyriboaldolase
      Short name=DERA

Gene names

Name:	deoC
Ordered Locus Names:	BT_4425

Organism

Bacteroides thetaiotaomicron [Complete proteome] [HAMAP]

Taxonomic identifier

818 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	238 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde. HAMAP MF_00114
Pathway	Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2. HAMAP MF_00114
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Schiff base
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate catabolic process Inferred from electronic annotation. Source: HAMAP deoxyribonucleotide catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	deoxyribose-phosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 238	238	Deoxyribose-phosphate aldolase HAMAP MF_00114		PRO_0000057225
Sites
	Active site	168	1	Schiff-base intermediate with acetaldehyde By similarity
	Active site	197	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q89ZF2-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 7AE3BE59FCB8B5FF	FASTA	238	25,398
	10 20 30 40 50 60 MEKKNINEVI ANLSVEQLAG MIDHTFLKPF GTAENIEKLC AEARQYQFAM VAINPAEVET 70 80 90 100 110 120 CVKLLEGSGV RVGAAIGFPL GQNTVECKAF ETRDAIAKGA TEIDTVINVR ALQKGQTDIV 130 140 150 160 170 180 KKEIEDMVSI CKPAGVICKV ILETCYLTDE EKETVCRIAK EAGVDFVKTS TGFGTAGANV 190 200 210 220 230 HDVALMRRVV GPVIGVKAAG GIRDLDTALA LIQVGATRIG TSSGIQIVEA YKELKKGL

References

[1]

"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis." Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I. Science 299:2074-2076(2003) [PubMed: 12663928] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE015928 Genomic DNA. Translation: AAO79530.1.
RefSeq	NP_813336.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1071696.
GenomeReviews	Gene locus BT_4425 in contig AE015928_GR.
KEGG	bth:BT_4425.
NMPDR	fig|226186.1.peg.4423.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q89ZF2.
OMA	AKMIDHT.
Enzyme and pathway databases
BioCyc	BTHE226186:BT_4425-MON.
BRENDA	4.1.2.4. 21018.
Family and domain databases
HAMAP	MF_00114. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR011343. DeoC. IPR002915. DeoC/AroFGH_arch. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHER	PTHR10889. DeoC. 1 hit.
Pfam	PF01791. DeoC. 1 hit. [Graphical view]
PIRSF	PIRSF001357. DeoC. 1 hit.
TIGRFAMs	TIGR00126. deoC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DEOC_BACTN

Accession

Primary (citable) accession number: Q89ZF2

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 26, 2004
Last sequence update:	June 1, 2003
Last modified:	November 3, 2009
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)