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Reviewed, UniProtKB/Swiss-Prot Q89YZ2 (PTH_BACTN)

Last modified November 3, 2009. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Peptidyl-tRNA hydrolase
      Short name=PTH
    EC=3.1.1.29
Gene names
Name: pth
Ordered Locus Names: BT_4588
OrganismBacteroides thetaiotaomicron [Complete proteome] [HAMAP]
Taxonomic identifier818 [NCBI]
Taxonomic lineageBacteriaBacteroidetesBacteroidiaBacteroidalesBacteroidaceaeBacteroides

Protein attributes

Sequence length189 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis By similarity.

Catalytic activity

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. HAMAP MF_00083

Subunit structure

Monomer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the PTH family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtranslation

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionaminoacyl-tRNA hydrolase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 189189Peptidyl-tRNA hydrolase HAMAP MF_00083
PRO_0000187693

Sequences

Sequence LengthMass (Da)Tools
Q89YZ2-1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 7C177DEF62074540

FASTA18921,089
        10         20         30         40         50         60 
MIKYLIVGLG NIGPEYHETR HNIGFMTVEA LARINNAPPF IDGRYGFTTS FSIKGRQLIL 

        70         80         90        100        110        120 
LKPSTFMNLS GLAVRYWMQK ENIPLENVLI VVDDLALPFG TLRLKGKGSD AGHNGLKHIA 

       130        140        150        160        170        180 
AILGTQNYAR LRFGIGNDFP KGGQIDYVLG HFTDEDRKTM DERLETAGEI IKSFCLAGID 


ITMNQFNKK 

« Hide

References

[1]"A genomic view of the human-Bacteroides thetaiotaomicron symbiosis."
Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C., Hooper L.V., Gordon J.I.
Science 299:2074-2076(2003) [PubMed: 12663928] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482.

Cross-references

Sequence databases

AE015928 Genomic DNA. Translation: AAO79693.1.
RefSeqNP_813499.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID1072118.
GenomeReviewsGene locus BT_4588 in contig AE015928_GR.
KEGGbth:BT_4588.
NMPDRfig|226186.1.peg.4586.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ89YZ2.
OMAIKFKTGG.

Enzyme and pathway databases

BioCycBTHE226186:BT_4588-MON.
BRENDA3.1.1.29. 21018.

Family and domain databases

HAMAPMF_00083.
[Tree]
InterProIPR001328. Pept_tRNA_hydro.
IPR018171. Pept_tRNA_hydro_CS.
[Graphical view]
Gene3DG3DSA:3.40.50.1470. Pept_tRNA_hydro. 1 hit.
PANTHERPTHR17224. Pept_tRNA_hydro. 1 hit.
PfamPF01195. Pept_tRNA_hydro. 1 hit.
[Graphical view]
ProDomPD005324. PeptRNAhydrolase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsTIGR00447. pth. 1 hit.
PROSITEPS01195. PEPT_TRNA_HYDROL_1. 1 hit.
PS01196. PEPT_TRNA_HYDROL_2. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePTH_BACTN
AccessionPrimary (citable) accession number: Q89YZ2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: June 1, 2003
Last modified: November 3, 2009
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents