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Reviewed, UniProtKB/Swiss-Prot Q89XW8 (AROB_BRAJA)

Last modified February 9, 2010. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    3-dehydroquinate synthase
    EC=4.2.3.4
Gene names
Name: aroB
Ordered Locus Names: bll0187
OrganismBradyrhizobium japonicum [Complete proteome] [HAMAP]
Taxonomic identifier375 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium

Protein attributes

Sequence length382 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

NAD By similarity. HAMAP MF_00110

Divalent metal cations By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm Probable HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3823823-dehydroquinate synthase HAMAP MF_00110
PRO_0000140714

Sequences

Sequence LengthMass (Da)Tools
Q89XW8-1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 13189D8699216EE8

FASTA38240,277
        10         20         30         40         50         60 
MTAPLKHSDP VNVDVALGDR AYDIVIGRGV LASLGERVAA LRPGVRTAVV TDRTVAKHWL 

        70         80         90        100        110        120 
EPTEASLAAA GIPTSRIVVE EGEISKTYAG LEKVSEALIA AKIERNDLVI ALGGGVVGDL 

       130        140        150        160        170        180 
AGFAAAILRR GVDFVQVPTS LLAQVDSSVG GKTGINSPQG KNLLGAFHQP VLVIADTAVL 

       190        200        210        220        230        240 
DTLSPRQFHA GYAEVAKYGV LGDEAFFTWL EKNHSDIFKG GSAREHAIAT SCRAKAGIVS 

       250        260        270        280        290        300 
RDERETGERA LLNLGHTFGH ALEAATGFSD RLFHGEGVAI GMTLAAQFSA KLGMIGEADA 

       310        320        330        340        350        360 
ARVERHLIEA GLPTRLQDIA GFSQEGLADA DALMALMAQD KKVKRGKLTF ILLEAVGRAV 

       370        380 
IAKDVEPAPV RDFLKEKLAQ KA 

« Hide

References

[1]"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110."
Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.
DNA Res. 9:189-197(2002) [PubMed: 12597275] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: USDA 110.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000040 Genomic DNA. Translation: BAC45452.1.
RefSeqNP_766827.1.

3D structure databases

SMRQ89XW8. Positions 17-373.
ModBaseSearch...

Genome annotation databases

GeneID1049146.
GenomeReviewsGene locus bll0187 in contig BA000040_GR.
KEGGbja:bll0187.
NMPDRfig|224911.1.peg.187.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG632303.
OMAAPESMDF.
PhylomeDBQ89XW8.

Enzyme and pathway databases

BioCycBJAP224911:BLL0187-MONOMER.
BRENDA4.2.3.4. 280.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016303. DHQ_synth.
IPR002658. DHQ_synth_AroB.
IPR016037. DHQ_synth_AroB_sub.
[Graphical view]
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PfamPF01761. DHQ_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. aroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_BRAJA
AccessionPrimary (citable) accession number: Q89XW8
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: June 1, 2003
Last modified: February 9, 2010
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents