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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Tricarboxylic acid cycle

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

BioCyciBJAP224911:GJEJ-285-MONOMER.
UniPathwayiUPA00223; UER01008.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:bll0284
OrganismiBradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Taxonomic identifieri224911 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
Proteomesi
  • UP000002526 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 512512Probable malate:quinone oxidoreductasePRO_0000128707Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224911.bll0284.

Structurei

3D structure databases

ProteinModelPortaliQ89XM4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
HOGENOMiHOG000109379.
InParanoidiQ89XM4.
KOiK00116.
OMAiDLSRQFW.
OrthoDBiPOG091H0B7C.
PhylomeDBiQ89XM4.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.

Sequencei

Sequence statusi: Complete.

Q89XM4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPAASDRETD VVLIGAGIMS ATLGAFLKEL EPSLTIQMLE TLDDCAQESS
60 70 80 90 100
DSWNNAGTGH AANCEMNYTP QRPDGSIDIS KALQVNVEFD LSRQFWSYLI
110 120 130 140 150
GRGAIADPRS FIHPVPHMSF VHGTENVEFL RKRFKAMSAH HCYEGMEHTE
160 170 180 190 200
DPRKIAEWAP LVMDGRSGDE PVAATRIITG TDVDYGALTH LLVGHLVSQP
210 220 230 240 250
GCAVHYNSCV TGLVREQGGR WRIEVRDTAS GETRSVRAKF VFIGAGGGAL
260 270 280 290 300
PLLEKSGLPE ARGYGGFPVS GIWLRCDDPE INKRHHAKVY GKAAVGSPPM
310 320 330 340 350
SVPHLDTRVI GGKHSLLFGP YAGFSSKFLK HGSLLDLFES IRPANVKPLL
360 370 380 390 400
SVARDNFDLT EYLVGQVLQS ESHRLAALDE YFPKADPKDW RLQVAGQRVQ
410 420 430 440 450
IIKPDVKRGG LLEFGTELVG ADDHSLVALL GASPGASTAA FIAISVLEKC
460 470 480 490 500
FAGELTASAW LPKLKQIVPS YGVSLIDDAD FCRQIRATTA EVLKVDNIPQ
510
PAARAPAAAK RA
Length:512
Mass (Da):55,455
Last modified:June 1, 2003 - v1
Checksum:i5B0FF5455898F765
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000040 Genomic DNA. Translation: BAC45549.1.
RefSeqiNP_766924.1. NC_004463.1.
WP_011083116.1. NC_004463.1.

Genome annotation databases

EnsemblBacteriaiBAC45549; BAC45549; BAC45549.
GeneIDi1050556.
KEGGibja:bll0284.
PATRICi21183999. VBIBraJap65052_0279.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000040 Genomic DNA. Translation: BAC45549.1.
RefSeqiNP_766924.1. NC_004463.1.
WP_011083116.1. NC_004463.1.

3D structure databases

ProteinModelPortaliQ89XM4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224911.bll0284.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC45549; BAC45549; BAC45549.
GeneIDi1050556.
KEGGibja:bll0284.
PATRICi21183999. VBIBraJap65052_0279.

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
HOGENOMiHOG000109379.
InParanoidiQ89XM4.
KOiK00116.
OMAiDLSRQFW.
OrthoDBiPOG091H0B7C.
PhylomeDBiQ89XM4.

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.
BioCyciBJAP224911:GJEJ-285-MONOMER.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
HAMAPiMF_00212. MQO. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR006231. MQO.
[Graphical view]
PfamiPF06039. Mqo. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiMQO_BRADU
AccessioniPrimary (citable) accession number: Q89XM4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 2003
Last sequence update: June 1, 2003
Last modified: September 7, 2016
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.