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Reviewed, UniProtKB/Swiss-Prot Q89XH1 (HGD_BRAJA)

Last modified January 20, 2009. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Homogentisate 1,2-dioxygenase
    EC=1.13.11.5
Alternative name(s):
    Homogentisicase
    Homogentisate oxygenase
    Homogentisic acid oxidase
Gene names
Name: hmgA
Ordered Locus Names: bll0343
OrganismBradyrhizobium japonicum [Complete proteome] [HAMAP]
Taxonomic identifier375 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium

Protein attributes

Sequence length448 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

Homogentisate + O2 = 4-maleylacetoacetate. HAMAP MF_00334

Cofactor

Iron By similarity.

Pathway

Amino-acid degradation; L-phenylalanine degradation; acetoacetic acid and fumarate from L-phenylalanine: step 4/6. HAMAP MF_00334

Sequence similarities

Belongs to the homogentisate dioxygenase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 448448Homogentisate 1,2-dioxygenase HAMAP MF_00334
PRO_0000220246

Sites

Metal binding3461Iron By similarity
Metal binding3521Iron By similarity
Metal binding3821Iron By similarity

Sequences

Sequence LengthMass (Da)Tools
Q89XH1-1 [UniParc].

Last modified June 6, 2003. Version 1.
Checksum: F6DD465E68735D3C

FASTA44849,780
        10         20         30         40         50         60 
MNINTSPDQI IRSSAQVTPG YMSGFGNSFE TEALPGALPI GRNSPQRCAY GLYAEQLSGS 

        70         80         90        100        110        120 
PFTAPRGTNE RSWLYRIRPS VKHSGRFEKA DAGLWRSAPC HEYDLPIAQM RWDPTPVPKE 

       130        140        150        160        170        180 
EVTFVQGVQT MTTAGDVNTQ AGMAAHVYLI TKSMVDQHFY NADGELMFVL QQGNLRLVTE 

       190        200        210        220        230        240 
FGRIDAEPGE IVVIPRGVKF RVEIPNGPAR GYLCENYGGA FTLPERGPIG ANCLANARDF 

       250        260        270        280        290        300 
LTPVANYEDK DTPTELFVKW GGSLFKTTLP HSPIDVVAWH GNYAPYKYDL RTFSPVGAIG 

       310        320        330        340        350        360 
FDHPDPSIFT VLTSPSETAG TANIDFVIFP ERWMVADNTF RPPWYHMNIM SEFMGLIYGV 

       370        380        390        400        410        420 
YDAKPQGFVP GGMSLHNCML PHGPDRDAFE HASNGELKPV KLTGTMAFMF ETRYPQRVTA 

       430        440 
HAANASTLQD DYADCWKGLE KRFDPNRP 

« Hide

References

[1]"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110."
Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.
DNA Res. 9:189-197(2002) [PubMed: 12597275] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: USDA 110.

Cross-references

Sequence databases

BA000040 Genomic DNA. Translation: BAC45608.1. Different initiation.
RefSeqNP_766983.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID1053162.
GenomeReviewsGene locus bll0343 in contig BA000040_GR.
KEGGbja:bll0343.
NMPDRfig|224911.1.peg.343.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ89XH1.

Enzyme and pathway databases

BioCycBJAP224911:BLL0343-MON.
BRENDA1.13.11.5. 280.

Family and domain databases

HAMAPMF_00334.
[Tree]
InterProIPR005708. Homogentis_dOase.
[Graphical view]
PANTHERPTHR11056. Homogentis_dOase. 1 hit.
PfamPF04209. HgmA. 1 hit.
[Graphical view]
TIGRFAMsTIGR01015. hmgA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameHGD_BRAJA
AccessionPrimary (citable) accession number: Q89XH1
Entry history
Integrated into UniProtKB/Swiss-Prot: June 6, 2003
Last sequence update: June 6, 2003
Last modified: January 20, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents