ID   Q89XF5_BRADU            Unreviewed;       815 AA.
AC   Q89XF5;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 115.
DE   SubName: Full=Blr0359 protein {ECO:0000313|EMBL:BAC45624.1};
GN   OrderedLocusNames=blr0359 {ECO:0000313|EMBL:BAC45624.1};
OS   Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 /
OS   NBRC 14792 / USDA 110).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Nitrobacteraceae; Bradyrhizobium.
OX   NCBI_TaxID=224911 {ECO:0000313|EMBL:BAC45624.1, ECO:0000313|Proteomes:UP000002526};
RN   [1] {ECO:0000313|Proteomes:UP000002526}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110
RC   {ECO:0000313|Proteomes:UP000002526};
RX   PubMed=12597275; DOI=10.1093/dnares/9.6.189;
RA   Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S.,
RA   Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M.,
RA   Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
RT   "Complete genomic sequence of nitrogen-fixing symbiotic bacterium
RT   Bradyrhizobium japonicum USDA110.";
RL   DNA Res. 9:189-197(2002).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the adenylyl cyclase class-3 family.
CC       {ECO:0000256|ARBA:ARBA00005381}.
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DR   EMBL; BA000040; BAC45624.1; -; Genomic_DNA.
DR   RefSeq; NP_766999.1; NC_004463.1.
DR   RefSeq; WP_011083191.1; NZ_CP011360.1.
DR   AlphaFoldDB; Q89XF5; -.
DR   STRING; 224911.AAV28_41035; -.
DR   EnsemblBacteria; BAC45624; BAC45624; BAC45624.
DR   GeneID; 64020217; -.
DR   KEGG; bja:blr0359; -.
DR   PATRIC; fig|224911.44.peg.8883; -.
DR   eggNOG; COG2114; Bacteria.
DR   eggNOG; COG3850; Bacteria.
DR   HOGENOM; CLU_018096_0_0_5; -.
DR   InParanoid; Q89XF5; -.
DR   OrthoDB; 9762462at2; -.
DR   Proteomes; UP000002526; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0006171; P:cAMP biosynthetic process; IBA:GO_Central.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd18774; PDC2_HK_sensor; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR43081:SF16; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC; 1.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF158472; HAMP domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002526};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        16..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        284..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          304..356
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          620..751
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   COILED          355..382
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   815 AA;  88917 MW;  60046A2401B05704 CRC64;
     MAGANDKTRF LREGLFAKYV VSLVGLVVFV LAVSGAMETW ISYRATKTQL TDGLEDKAQA
     AARRVEQSIS ELERQISWVT RASQDTLEKR RADYAQLLHQ VAVVNQLFQL NGEGREVLRV
     SRQSTTTGGN ADLSRDMRFT DTVARGVSYA PAWFSDRTPL MSISVAHSGF NAGVTVAEID
     LSFLSELLSD AQVGKAAFAY VVDPRGRVLA TSSKGPDVGK DLSKLPQVAA AISPGRGPDT
     SGTDFNGYSV LTAASTVPKL GWSVLFEQPT TQALTPIRDQ LVRIALLIGM GLMVAILAGT
     LLARRMIIPI TALRDGAHKL GEGDFSHRID VHTSDELEDL AGQFNRMATQ IQETYSNLET
     KVEERTRDLA QSINELKVLE EVGRAVASSL DLNAVLPTIA ARAIEITHAD AVLIYGFDAG
     TRRFNLVESN GIDKSADGAH VTIDEGDNIL SDAAASCEPI ALADLDHAAE QPLRDVAIAA
     GFHSVLVVPL VDQQGTLGSL VVLRRAGGEF AASIIGLMRT FANQAVLAMR NARLFTEVDH
     KSHALEAAHE TVRAQADKLR VQTEQLKDWN KSLEERVEKQ LGEIERIRKL ERFLAPQVAQ
     LIASSDSPEG LLTSQRREVT VVFCDLRGFT AFTEATEPEE AMNVLREYHA ALGTLIFKYE
     GTLDKYAGDG VMILFNAPIQ FEDHTQRAVK MAVEMRDTIG PLTERWRNRG HSLGFGIGIA
     LGYATLGQVG FEQRLEYAAI GSVTNLASRL CGEAKANQIV VSRRVYGMVE PWVEARALDD
     LVLKGFNHPV LAMEILSWRE EVDNVVDAAA ARRRG
//