Reviewed, UniProtKB/Swiss-Prot Q89WM2 (COAA_BRAJA)

Names and origin

Protein names

Recommended name:
    Pantothenate kinase
    EC=2.7.1.33
Alternative name(s):
    Pantothenic acid kinase

Gene names

Name:	coaA
Synonyms:	panK
Ordered Locus Names:	blr0656

Organism

Bradyrhizobium japonicum [Complete proteome] [HAMAP]

Taxonomic identifier

375 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length	318 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate. HAMAP MF_00215
Pathway	Cofactor biosynthesis; coenzyme A biosynthesis; coenzyme A from pantothenate: step 1/5. HAMAP MF_00215
Subcellular location	Cytoplasm Probable.
Sequence similarities	Belongs to the prokaryotic pantothenate kinase family.

Ontologies

Keywords
Biological process	Coenzyme A biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme A biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP pantothenate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 318	318	Pantothenate kinase HAMAP MF_00215		PRO_0000194420
Regions
	Nucleotide binding	96 – 103	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q89WM2-1 [UniParc]. Last modified June 20, 2003. Version 1. Checksum: 07FB31D15C5471C1	FASTA	318	36,712
	10 20 30 40 50 60 MDIRAPEQQY NPYRVYTREQ WARLRDDTPM TLEPGEFDRL RSLHDRLDLQ EVEDIYLPLS 70 80 90 100 110 120 RLLSIYVDAM QRLYYAERQF LNIRDRKMPY IIGVAGSVAV GKSTTARVLQ ALLARWSPRP 130 140 150 160 170 180 KVDLITTDGF LYPNAVLDRQ GIMQKKGFPE SYDLPLLLGF LSDIKAGRRH VRAPVYSHLT 190 200 210 220 230 240 YDIVPNQWVE IDQPDILIVE GVNVLQTGKL PRDGKAVPVV SDFFDFSVYI DADEAALRRW 250 260 270 280 290 300 YIKRFLALRD TAFTNPKSYF NRYALLSDEE ATATAIAIWE RTNLANLEDN ILPTRPRATL 310 ILKKGPDHVV ESVALRRL

References

[1]

"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110." Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S. DNA Res. 9:189-197(2002) [PubMed: 12597275] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: USDA 110.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000040 Genomic DNA. Translation: BAC45921.1. Different initiation.
RefSeq	NP_767296.1.
3D structure databases
HSSP	HSSP built from PDB template 1ESM based on UniProtKB P15044.
ModBase	Search...
Genome annotation databases
GeneID	1049340.
GenomeReviews	Gene locus blr0656 in contig BA000040_GR.
KEGG	bja:blr0656.
NMPDR	fig|224911.1.peg.656.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q89WM2.
Enzyme and pathway databases
BioCyc	BJAP224911:BLR0656-MON.
BRENDA	2.7.1.33. 280.
Family and domain databases
HAMAP	MF_00215. [Tree]
InterPro	IPR004566. PanK_bact. [Graphical view]
PANTHER	PTHR10285:SF7. PanK_bact. 1 hit.
PIRSF	PIRSF000545. Pantothenate_kin. 1 hit.
TIGRFAMs	TIGR00554. panK_bact. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COAA_BRAJA

Accession

Primary (citable) accession number: Q89WM2

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 20, 2003
Last sequence update:	June 20, 2003
Last modified:	June 16, 2009
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)