Reviewed, UniProtKB/Swiss-Prot Q89WK5 (NTPA_BRAJA)

Names and origin

Protein names

Recommended name:
    Nucleoside-triphosphatase
    EC=3.6.1.15
Alternative name(s):
    Nucleoside triphosphate phosphohydrolase
      Short name=NTPase

Gene names

Ordered Locus Names:

bll0673

Organism

Bradyrhizobium japonicum [Complete proteome] [HAMAP]

Taxonomic identifier

375 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length	211 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions By similarity.
Catalytic activity	NTP + H2O = NDP + phosphate. HAMAP MF_01405
Cofactor	Divalent cations By similarity.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the HAM1 NTPase family.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	nucleoside-triphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 211	211	Nucleoside-triphosphatase HAMAP MF_01405		PRO_0000178140

Sequences

	Sequence		Length	Mass (Da)
	Q89WK5-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: BAB4CF5EBE236A3B	FASTA	211	22,761
	10 20 30 40 50 60 MHRRITGKLV IATHNPGKLA EMKELLAPYG IEAVSAGELG LSEPDETGND FRSNAAIKAI 70 80 90 100 110 120 AAAHASKLPS FADDSGIVVD ALDGAPGIYS ARWAGPTKDF TAAMTRIERL LQERGATAPD 130 140 150 160 170 180 KRKAHFVSAL CVAWPDDHLE EVEARVDGTL VWPPRGTAGF GYDPMFRPDG HTRTFGEMTS 190 200 210 IEKHGLPPLG LALSHRARAF VKLAEICLEP R

References

[1]

"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110." Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S. DNA Res. 9:189-197(2002) [PubMed: 12597275] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: USDA 110.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000040 Genomic DNA. Translation: BAC45938.1.
RefSeq	NP_767313.1.
3D structure databases
HSSP	HSSP built from PDB template 1K7K based on UniProtKB P52061.
ModBase	Search...
Genome annotation databases
GeneID	1049315.
GenomeReviews	Gene locus bll0673 in contig BA000040_GR.
KEGG	bja:bll0673.
NMPDR	fig|224911.1.peg.673.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q89WK5.
OMA	Q89WK5. VYTADWA.
Enzyme and pathway databases
BioCyc	BJAP224911:BLL0673-MON.
BRENDA	3.6.1.15. 280.
Family and domain databases
HAMAP	MF_01405. [Tree]
InterPro	IPR002637. Ham1p-like. [Graphical view]
PANTHER	PTHR11067. Ham1p_like. 1 hit.
Pfam	PF01725. Ham1p_like. 1 hit. [Graphical view]
TIGRFAMs	TIGR00042. Ham1p_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

NTPA_BRAJA

Accession

Primary (citable) accession number: Q89WK5

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 26, 2005
Last sequence update:	June 1, 2003
Last modified:	June 16, 2009
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)