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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciBJAP224911:GJEJ-752-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation (EC:5.3.1.24UniRule annotation)
Short name:
PRAIUniRule annotation
Gene namesi
Name:trpFUniRule annotation
Ordered Locus Names:blr0744
OrganismiBradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Taxonomic identifieri224911 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
ProteomesiUP000002526 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 223223N-(5'-phosphoribosyl)anthranilate isomerasePRO_1000018582Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224911.blr0744.

Structurei

3D structure databases

ProteinModelPortaliQ89WE6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
InParanoidiQ89WE6.
KOiK01817.
OrthoDBiEOG6N94DF.
PhylomeDBiQ89WE6.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

Q89WE6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLLVKICGL STRETLETAL DAGADMVGFV FFPPSPRHLS LELGRDLGRQ
60 70 80 90 100
VNRRALKVAL TVDADDATLD NIMDALSPDI FQLHGKETVA RLRDIKQRFG
110 120 130 140 150
RPVMKAVPVA TSADLAVLPG YAAVADRILF DARAPKDATR PGGLGAPFDW
160 170 180 190 200
HLLENLDLNL PYMVSGGLHA DNVAEALRIT RAGGVDVSSG VESAPGVKDP
210 220
EMIKAFIRAA RATQDASQEL SVR
Length:223
Mass (Da):23,923
Last modified:June 1, 2003 - v1
Checksum:i90ABB4F3BC909652
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000040 Genomic DNA. Translation: BAC46009.1.
RefSeqiNP_767384.1. NC_004463.1.
WP_011083568.1. NC_004463.1.

Genome annotation databases

EnsemblBacteriaiBAC46009; BAC46009; BAC46009.
GeneIDi1047874.
KEGGibja:blr0744.
PATRICi21184992. VBIBraJap65052_0768.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000040 Genomic DNA. Translation: BAC46009.1.
RefSeqiNP_767384.1. NC_004463.1.
WP_011083568.1. NC_004463.1.

3D structure databases

ProteinModelPortaliQ89WE6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224911.blr0744.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC46009; BAC46009; BAC46009.
GeneIDi1047874.
KEGGibja:blr0744.
PATRICi21184992. VBIBraJap65052_0768.

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
InParanoidiQ89WE6.
KOiK01817.
OrthoDBiEOG6N94DF.
PhylomeDBiQ89WE6.

Enzyme and pathway databases

UniPathwayiUPA00035; UER00042.
BioCyciBJAP224911:GJEJ-752-MONOMER.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110.

Entry informationi

Entry nameiTRPF_BRADU
AccessioniPrimary (citable) accession number: Q89WE6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 1, 2003
Last modified: May 27, 2015
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.