Q89W59 (Q89W59_BRAJA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP-Rule MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP-Rule MF_01401
EC=1.8.4.11 HAMAP-Rule MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP-Rule MF_01401

Gene names

Name:	msrA HAMAP-Rule MF_01401 EMBL BAC46099.1
Ordered Locus Names:	blr0834

Organism

Bradyrhizobium japonicum (strain USDA 110) [Reference proteome] [HAMAP] EMBL BAC46099.1

Taxonomic identifier

224911 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium › Bradyrhizobium japonicum

Protein attributes

Sequence length	218 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP-Rule MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP-Rule MF_01401 SAAS SAAS002569 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP-Rule MF_01401 SAAS SAAS002569
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP-Rule MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP-Rule MF_01401 SAAS SAAS002569
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cellular protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular_function	peptide-methionine (S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	54	1	By similarity HAMAP-Rule MF_01401

Sequences

	Sequence		Length	Mass (Da)
	Q89W59 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: C056AA1790C1F38E	FASTA	218	23,305
	10 20 30 40 50 60 MLFMRKTTAL PSATEALPGR AQAIPTASTH FVNGSKLQPP YPAGLEQAVF GLGCFWGAER 70 80 90 100 110 120 KFWELGDGVY TTAVGYAGGH TPNPTYEETC SGRTGHTEVV LVVFDPKKVS YEKLLKTFWE 130 140 150 160 170 180 SHNPTQGMRQ GNDVGTQYRS AIYTYSDAQK KAADESKALY QKALAAKGLG AITTEIAPAG 190 200 210 AFYFAEDYHQ QYLAKNPAGY CGLGGTGVSC PIGVGVSA

References

[1]

"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110." Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S. DNA Res. 9:189-197(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: USDA 110.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000040 Genomic DNA. Translation: BAC46099.1.
RefSeq	NP_767474.1. NC_004463.1.
3D structure databases
ProteinModelPortal	Q89W59.
SMR	Q89W59. Positions 12-211.
ModBase	Search...
Protein-protein interaction databases
STRING	224911.blr0834.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAC46099; BAC46099; BAC46099.
GeneID	1049129.
KEGG	bja:blr0834.
PATRIC	21185174. VBIBraJap65052_0859.
Phylogenomic databases
HOGENOM	HOG000263862.
KO	K07304.
OMA	SAIYCTT.
ProtClustDB	PRK00058.
Enzyme and pathway databases
BioCyc	BJAP224911:GJEJ-842-MONOMER.
Family and domain databases
Gene3D	3.30.1060.10. 1 hit.
HAMAP	MF_01401. MsrA.
InterPro	IPR002569. Met_Sox_Rdtase_MsrA. [Graphical view]
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. msrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q89W59_BRAJA

Accession

Primary (citable) accession number: Q89W59

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	May 29, 2013
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)