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Protein

DNA mismatch repair protein MutS

Gene

mutS

Organism
Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi661 – 6688ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA repair

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBJAP224911:GJEJ-933-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA mismatch repair protein MutSUniRule annotation
Gene namesi
Name:mutSUniRule annotation
Ordered Locus Names:bll0924
OrganismiBradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Taxonomic identifieri224911 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
Proteomesi
  • UP000002526 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 912912DNA mismatch repair protein MutSPRO_0000115076Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224911.bll0924.

Structurei

3D structure databases

ProteinModelPortaliQ89VX1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DNA mismatch repair MutS family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D86. Bacteria.
COG0249. LUCA.
HOGENOMiHOG000221407.
InParanoidiQ89VX1.
KOiK03555.
OrthoDBiEOG6Q5NPV.
PhylomeDBiQ89VX1.

Family and domain databases

Gene3Di3.30.420.110. 1 hit.
3.40.1170.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00096. MutS.
InterProiIPR005748. DNA_mismatch_repair_MutS-1.
IPR007695. DNA_mismatch_repair_MutS-lik_N.
IPR000432. DNA_mismatch_repair_MutS_C.
IPR007861. DNA_mismatch_repair_MutS_clamp.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR016151. DNA_mismatch_repair_MutS_N.
IPR007860. DNA_mmatch_repair_MutS_con_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01624. MutS_I. 1 hit.
PF05188. MutS_II. 1 hit.
PF05192. MutS_III. 1 hit.
PF05190. MutS_IV. 1 hit.
PF00488. MutS_V. 1 hit.
[Graphical view]
SMARTiSM00534. MUTSac. 1 hit.
SM00533. MUTSd. 1 hit.
[Graphical view]
SUPFAMiSSF48334. SSF48334. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF53150. SSF53150. 1 hit.
SSF55271. SSF55271. 1 hit.
TIGRFAMsiTIGR01070. mutS1. 1 hit.
PROSITEiPS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q89VX1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTMQQPIPVP PPDETPAPQA EAAARVTPMM EQYLEIKAAH QGLLLFYRMG
60 70 80 90 100
DFYELFFEDA EIASKTLGIV LTKRGKHQGA DIPMCGVPVE RAEDYLHRLI
110 120 130 140 150
SAGHRVAVCE QTEDPAAAKA RGNKSVVRRG VVRLVTPGTL TEDTLLDARA
160 170 180 190 200
NNYLLAIARA RSSTGGDRFG LAWIDISTAE FMVTECSGGE LAATLARINP
210 220 230 240 250
NEAIVTDALY NDNELGQTLR ELPAVTPLTR DVFDGATAEK RLCDYFAVAT
260 270 280 290 300
MDGLAQLTRL EATAASAAVT YVDRTQVGRH PPLSPPAREA SGATMAIDPA
310 320 330 340 350
TRANLELTRT LAGERRGSLL DAIDCTVTSA GSRLLAQRLA APLTDAPAIA
360 370 380 390 400
RRLDAVGAFV ADSAAREDIR SILRGAPDMS RALARLSVGR GGPRDLAGLR
410 420 430 440 450
DGIIAADQVL ARLGELDQPP QEIAAVMAAL TRPSRELAAE FATALDEQLP
460 470 480 490 500
LIKRDGGFVR QGYEPALDEA RNLRDASRLV VASMQARYAD DTGVKGLKIR
510 520 530 540 550
HNNVLGYFVE VTAQHGDKLM SAPLNATFIH RQTLAGQIRF TTSELGEIEA
560 570 580 590 600
KIANAGDRAL GLELEIFERL CAKALEISDD LRAAAQGFAL LDVATSLAKL
610 620 630 640 650
AVDENYVRPE VDSSLGFAIE AGRHPVVEQA LKRNGEPFIA NACDLSPAPA
660 670 680 690 700
QKSGQLWLLT GPNMAGKSTF LRQNALIALL AQIGSFVPAT RARIGIIDRL
710 720 730 740 750
FSRVGAADDL ARGRSTFMVE MVETAAILNQ AGERALVILD EIGRGTATFD
760 770 780 790 800
GLSIAWAAIE HLHESNRCRT LFATHYHELT ALSAKLPRMF NATVRVKEWQ
810 820 830 840 850
GNVVFLHEVL PGSADRSYGI QVAKLAGLPP AVITRAKSVL AKLEAQDRGQ
860 870 880 890 900
TARALADDLP LFAVPSRAAA EAAPPSEAEL LMDAVKALHP DEMSPREALD
910
ALYALKAKLP KQ
Length:912
Mass (Da):97,983
Last modified:June 1, 2003 - v1
Checksum:iE1EA85780D31643A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000040 Genomic DNA. Translation: BAC46189.1.
RefSeqiNP_767564.1. NC_004463.1.
WP_011083746.1. NC_004463.1.

Genome annotation databases

EnsemblBacteriaiBAC46189; BAC46189; BAC46189.
GeneIDi1049823.
KEGGibja:bll0924.
PATRICi21185344. VBIBraJap65052_0943.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000040 Genomic DNA. Translation: BAC46189.1.
RefSeqiNP_767564.1. NC_004463.1.
WP_011083746.1. NC_004463.1.

3D structure databases

ProteinModelPortaliQ89VX1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224911.bll0924.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC46189; BAC46189; BAC46189.
GeneIDi1049823.
KEGGibja:bll0924.
PATRICi21185344. VBIBraJap65052_0943.

Phylogenomic databases

eggNOGiENOG4105D86. Bacteria.
COG0249. LUCA.
HOGENOMiHOG000221407.
InParanoidiQ89VX1.
KOiK03555.
OrthoDBiEOG6Q5NPV.
PhylomeDBiQ89VX1.

Enzyme and pathway databases

BioCyciBJAP224911:GJEJ-933-MONOMER.

Family and domain databases

Gene3Di3.30.420.110. 1 hit.
3.40.1170.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00096. MutS.
InterProiIPR005748. DNA_mismatch_repair_MutS-1.
IPR007695. DNA_mismatch_repair_MutS-lik_N.
IPR000432. DNA_mismatch_repair_MutS_C.
IPR007861. DNA_mismatch_repair_MutS_clamp.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR016151. DNA_mismatch_repair_MutS_N.
IPR007860. DNA_mmatch_repair_MutS_con_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01624. MutS_I. 1 hit.
PF05188. MutS_II. 1 hit.
PF05192. MutS_III. 1 hit.
PF05190. MutS_IV. 1 hit.
PF00488. MutS_V. 1 hit.
[Graphical view]
SMARTiSM00534. MUTSac. 1 hit.
SM00533. MUTSd. 1 hit.
[Graphical view]
SUPFAMiSSF48334. SSF48334. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF53150. SSF53150. 1 hit.
SSF55271. SSF55271. 1 hit.
TIGRFAMsiTIGR01070. mutS1. 1 hit.
PROSITEiPS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110.

Entry informationi

Entry nameiMUTS_BRADU
AccessioniPrimary (citable) accession number: Q89VX1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 2004
Last sequence update: June 1, 2003
Last modified: February 17, 2016
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.