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Reviewed, UniProtKB/Swiss-Prot Q89UU4 (KHSE_BRAJA)

Last modified June 16, 2009. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Homoserine kinase
      Short name=HSK
      Short name=HK
    EC=2.7.1.39
Gene names
Name: thrB
Ordered Locus Names: blr1315
OrganismBradyrhizobium japonicum [Complete proteome] [HAMAP]
Taxonomic identifier375 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium

Protein attributes

Sequence length327 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

ATP + L-homoserine = ADP + O-phospho-L-homoserine. HAMAP MF_00301

Pathway

Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5. HAMAP MF_00301

Sequence similarities

Belongs to the pseudomonas-type thrB family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Threonine biosynthesis
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processthreonine biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

homoserine kinase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 327327Homoserine kinase HAMAP MF_00301
PRO_0000172185

Sequences

Sequence LengthMass (Da)Tools
Q89UU4-1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: E141F9F97F66CF79

FASTA32735,819
        10         20         30         40         50         60 
MAVYTDVAAD ELADFLSQYD LGELLSYKGI AEGVENSNFL LHTTKGSFIL TLYEKRVAKN 

        70         80         90        100        110        120 
DLPFFLALMT HLAEHGVNCP LPVKGRDGEA LRELSGRPAA IITFLEGVWP RKPNAAHCAG 

       130        140        150        160        170        180 
VGEGLARMHL AGANFAIRRA NALSVAGWRP LFDAAASRAD EVQPGLRAFL AAELDYLASG 

       190        200        210        220        230        240 
VWPTNLPEGV IHADLFNDNV FFLGDKLSGI IDFTFACNDM LAYDVAICLN AWCFEPDHSF 

       250        260        270        280        290        300 
NVTKARAFLN AYGRVRKLSE AEEAALPLLA RGAAIRFLLT RLVDWLNVPP GALVRPKDPL 

       310        320 
EYVRKLRFHQ SVSSVRDYGL MPSGLVA 

« Hide

References

[1]"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110."
Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.
DNA Res. 9:189-197(2002) [PubMed: 12597275] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: USDA 110.

Cross-references

Sequence databases

BA000040 Genomic DNA. Translation: BAC46580.1.
RefSeqNP_767955.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID1049260.
GenomeReviewsGene locus blr1315 in contig BA000040_GR.
KEGGbja:blr1315.
NMPDRfig|224911.1.peg.1315.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ89UU4.
OMAQ89UU4. ADLFRDN.

Enzyme and pathway databases

BioCycBJAP224911:BLR1315-MON.
BRENDA2.7.1.39. 280.

Family and domain databases

HAMAPMF_00301.
[Tree]
InterProIPR002575. APH_trans.
IPR005280. Homoserine_Kinase_ThrB.
[Graphical view]
PfamPF01636. APH. 1 hit.
[Graphical view]
TIGRFAMsTIGR00938. thrB_alt. 1 hit.
ProtoNetSearch...

Entry information

Entry nameKHSE_BRAJA
AccessionPrimary (citable) accession number: Q89UU4
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2003
Last sequence update: June 1, 2003
Last modified: June 16, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents