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Q89UU4 (KHSE_BRAJA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Homoserine kinase

Short name=HK
Short name=HSK
EC=2.7.1.39
Gene names
Name:thrB
Ordered Locus Names:blr1315
OrganismBradyrhizobium japonicum
Taxonomic identifier375 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium

Protein attributes

Sequence length327 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-homoserine = ADP + O-phospho-L-homoserine. HAMAP MF_00301

Pathway

Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5. HAMAP MF_00301

Sequence similarities

Belongs to the pseudomonas-type thrB family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 327327Homoserine kinase HAMAP MF_00301
PRO_0000172185

Sequences

Sequence LengthMass (Da)Tools
Q89UU4 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: E141F9F97F66CF79

FASTA32735,819
        10         20         30         40         50         60 
MAVYTDVAAD ELADFLSQYD LGELLSYKGI AEGVENSNFL LHTTKGSFIL TLYEKRVAKN 

        70         80         90        100        110        120 
DLPFFLALMT HLAEHGVNCP LPVKGRDGEA LRELSGRPAA IITFLEGVWP RKPNAAHCAG 

       130        140        150        160        170        180 
VGEGLARMHL AGANFAIRRA NALSVAGWRP LFDAAASRAD EVQPGLRAFL AAELDYLASG 

       190        200        210        220        230        240 
VWPTNLPEGV IHADLFNDNV FFLGDKLSGI IDFTFACNDM LAYDVAICLN AWCFEPDHSF 

       250        260        270        280        290        300 
NVTKARAFLN AYGRVRKLSE AEEAALPLLA RGAAIRFLLT RLVDWLNVPP GALVRPKDPL 

       310        320 
EYVRKLRFHQ SVSSVRDYGL MPSGLVA 

« Hide

References

[1]"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110."
Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.
DNA Res. 9:189-197(2002) [PubMed: 12597275] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: USDA 110.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000040 Genomic DNA. Translation: BAC46580.1.
RefSeqNP_767955.1. NC_004463.1.

3D structure databases

ProteinModelPortalQ89UU4.
SMRQ89UU4. Positions 5-320.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1049260.
GenomeReviewsGene locus blr1315 in contig BA000040_GR.
KEGGbja:blr1315.
NMPDRfig|224911.1.peg.1315.
PATRIC21186182. VBIBraJap65052_1359.

Phylogenomic databases

HOGENOMHBG309377.
OMAICLNAWC.
ProtClustDBPRK05231.

Enzyme and pathway databases

BioCycBJAP224911:BLR1315-MONOMER.

Family and domain databases

HAMAPMF_00301. Homoser_kinase_2.
[Tree]
InterProIPR002575. Aminoglycoside_PTrfase.
IPR005280. Homoserine_kinase_ThrB.
IPR011009. Kinase-like_dom.
[Graphical view]
KOK02204.
PfamPF01636. APH. 1 hit.
[Graphical view]
SUPFAMSSF56112. Kinase_like. 1 hit.
TIGRFAMsTIGR00938. ThrB_alt. 1 hit.
ProtoNetSearch...

Entry information

Entry nameKHSE_BRAJA
AccessionPrimary (citable) accession number: Q89UU4
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2003
Last sequence update: June 1, 2003
Last modified: January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families