Reviewed, UniProtKB/Swiss-Prot Q89UL9 (HIS82_BRAJA)

Names and origin

Protein names

Recommended name:
    Histidinol-phosphate aminotransferase 2
    EC=2.6.1.9
Alternative name(s):
    Imidazole acetol-phosphate transaminase 2

Gene names

Name:	hisC2
Ordered Locus Names:	bll1397

Organism

Bradyrhizobium japonicum [Complete proteome] [HAMAP]

Taxonomic identifier

375 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length	365 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP MF_01023
Cofactor	Pyridoxal phosphate By similarity.
Pathway	Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP MF_01023
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Histidine biosynthesis
Ligand	Pyridoxal phosphate
Molecular function	Aminotransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	histidinol-phosphate transaminase activity Inferred from electronic annotation. Source: HAMAP pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 365	365	Histidinol-phosphate aminotransferase 2 HAMAP MF_01023		PRO_0000153326
Amino acid modifications
	Modified residue	221	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q89UL9-1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 890FB3D6A7678269	FASTA	365	39,892
	10 20 30 40 50 60 MSCPVPNPGI LDIAPYTPGK SPVPEPGRKV FKLSANETPF GPSPKAIEAF KKVADHLEDY 70 80 90 100 110 120 PEGTSRVLRE AIGRTFGLDP NRIICGAGSD EILNLLAHTY LGQGDEAIST THGFLVYPIA 130 140 150 160 170 180 TMAVGARNVI AQEKNLTCDV DAILKAVTPK TKLVWLANPN NPTGTYIPFD EVKRLRAGLP 190 200 210 220 230 240 SHVLLVLDAA YCDYVSRNDY EMGIELVATT ENTVVTHTFS KIHGLAALRI GWMFGPEHII 250 260 270 280 290 300 DAVNRIRGPF NVSTPAMYAA VAAIEDTAHQ AMSKQFTETW RNWLTEEIGK LGLKVTPSVA 310 320 330 340 350 360 NFVLIHFPTD RGRTSDDADA FLTKRGLVLR ALKNYGLPHS LRMTIGTEEA NRLVVDGLRD FMAGK

References

[1]

"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110." Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S. DNA Res. 9:189-197(2002) [PubMed: 12597275] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: USDA 110.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000040 Genomic DNA. Translation: BAC46662.1.
RefSeq	NP_768037.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1055142.
GenomeReviews	Gene locus bll1397 in contig BA000040_GR.
KEGG	bja:bll1397.
NMPDR	fig|224911.1.peg.1397.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q89UL9.
OMA	TTIVWIC.
Enzyme and pathway databases
BioCyc	BJAP224911:BLL1397-MON.
BRENDA	2.6.1.9. 280.
Family and domain databases
HAMAP	MF_01023. [Tree]
InterPro	IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR005861. HisP_aminotrans. IPR015421. PyrdxlP-dep_Trfase_major_sub1. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
TIGRFAMs	TIGR01141. hisC. 1 hit.
PROSITE	PS00599. AA_TRANSFER_CLASS_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HIS82_BRAJA

Accession

Primary (citable) accession number: Q89UL9

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 2003
Last sequence update:	June 1, 2003
Last modified:	November 3, 2009
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)