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Protein

D-amino acid dehydrogenase

Gene

dadA

Organism
Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Oxidative deamination of D-amino acids.UniRule annotation

Catalytic activityi

A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor.UniRule annotation

Cofactori

FADUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi3 – 1715FADUniRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

BioCyciBJAP224911:GJEJ-2243-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
D-amino acid dehydrogenaseUniRule annotation (EC:1.4.99.-UniRule annotation)
Gene namesi
Name:dadAUniRule annotation
Ordered Locus Names:blr2222
OrganismiBradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Taxonomic identifieri224911 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
Proteomesi
  • UP000002526 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 421421D-amino acid dehydrogenasePRO_0000166127Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224911.blr2222.

Structurei

3D structure databases

ProteinModelPortaliQ89T28.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DadA oxidoreductase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105MWK. Bacteria.
COG0665. LUCA.
HOGENOMiHOG000217450.
InParanoidiQ89T28.
KOiK00285.
OrthoDBiEOG6KMBD9.
PhylomeDBiQ89T28.

Family and domain databases

Gene3Di3.50.50.60. 4 hits.
HAMAPiMF_01202. DadA.
InterProiIPR023080. DadA.
IPR006076. FAD-dep_OxRdtase.
IPR023753. FAD/NAD-binding_dom.
IPR006036. K_uptake_TrkA.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
[Graphical view]
PRINTSiPR00335. KUPTAKETRKA.
SUPFAMiSSF51905. SSF51905. 3 hits.

Sequencei

Sequence statusi: Complete.

Q89T28-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVLILGSGV IGVTSAYYLA GAGHDVTVVD RQPEPALETS FANAGEVSPG
60 70 80 90 100
YSSPWAGPGV PVKAVKWLLM KHGPLVIRPK LDPVMWVWLL KMLRNCTSAR
110 120 130 140 150
YAVNKSRMIP IAEYSRDCLR DLRRDIGIQY DERSQGTLQL FRHQAQLDGT
160 170 180 190 200
GEDIAVLKQY GVPFEVLGRE GCIAVEPALA GVKEKFAGGL RLPQDETGDC
210 220 230 240 250
HMFTQALAKH AQALGVRFMF NTGIDRIVTD GARVSGVVTS AGVLQADAYV
260 270 280 290 300
LALGSWSSRL VAPLGISLPV YPVKGYSITV PIKDASGAPE STVMDESYKV
310 320 330 340 350
AITRLGNRIR VGGTAEISGF SSKLYDARRA TLDHSLTDLF PRGGDLSKAT
360 370 380 390 400
FWSGLRPMTP DGPPVIGPTQ YANLHLNTGH GTLGWTMSCG SGRVLADMLS
410 420
GKKPEVDVSA LTVDRYAHRF G
Length:421
Mass (Da):45,326
Last modified:June 1, 2003 - v1
Checksum:i4859B8F71BFCB76C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000040 Genomic DNA. Translation: BAC47487.1.
RefSeqiNP_768862.1. NC_004463.1.
WP_011085010.1. NC_004463.1.

Genome annotation databases

EnsemblBacteriaiBAC47487; BAC47487; BAC47487.
GeneIDi1055326.
KEGGibja:blr2222.
PATRICi21187770. VBIBraJap65052_2146.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000040 Genomic DNA. Translation: BAC47487.1.
RefSeqiNP_768862.1. NC_004463.1.
WP_011085010.1. NC_004463.1.

3D structure databases

ProteinModelPortaliQ89T28.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224911.blr2222.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC47487; BAC47487; BAC47487.
GeneIDi1055326.
KEGGibja:blr2222.
PATRICi21187770. VBIBraJap65052_2146.

Phylogenomic databases

eggNOGiENOG4105MWK. Bacteria.
COG0665. LUCA.
HOGENOMiHOG000217450.
InParanoidiQ89T28.
KOiK00285.
OrthoDBiEOG6KMBD9.
PhylomeDBiQ89T28.

Enzyme and pathway databases

BioCyciBJAP224911:GJEJ-2243-MONOMER.

Family and domain databases

Gene3Di3.50.50.60. 4 hits.
HAMAPiMF_01202. DadA.
InterProiIPR023080. DadA.
IPR006076. FAD-dep_OxRdtase.
IPR023753. FAD/NAD-binding_dom.
IPR006036. K_uptake_TrkA.
[Graphical view]
PfamiPF01266. DAO. 1 hit.
[Graphical view]
PRINTSiPR00335. KUPTAKETRKA.
SUPFAMiSSF51905. SSF51905. 3 hits.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110.

Entry informationi

Entry nameiDADA_BRADU
AccessioniPrimary (citable) accession number: Q89T28
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2003
Last sequence update: June 1, 2003
Last modified: November 11, 2015
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.