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Q89SS3 (PNCB_BRADU) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:bll2327
OrganismBradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110) [Reference proteome] [HAMAP]
Taxonomic identifier224911 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium

Protein attributes

Sequence length434 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 434434Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000146832

Sequences

Sequence LengthMass (Da)Tools
Q89SS3 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 8EC682BBC4396356

FASTA43449,902
        10         20         30         40         50         60 
MTVTDIASRT YNHSWRLDPI IRSLLDTDFY KLLMLQMIRE DYSNQQVTFS VINRSRHVRL 

        70         80         90        100        110        120 
AEIIDEGELR AQLDHARTIR FTKKELIWLA GNTFYGKTHM FSADFIRWLA EFRLPEYELR 

       130        140        150        160        170        180 
KVEGQYELHF HGPWTHTTMW EIPALAILNE LRSRAAIKGR GRFELDVLYA RAKAKLWTKV 

       190        200        210        220        230        240 
ERLRKLENLR LSDFGTRRRH GFLWQRWCVE AVKEGLGPSF IGTSNVLLAM DNDLEAIGTN 

       250        260        270        280        290        300 
AHELPMVAAG LAKDDEELRW APYRILDQWR QTYGGNLLIA LPDAFGTKAF LRDAPEWVAD 

       310        320        330        340        350        360 
WTGFRPDSAP PIQAGEEIIA WWEKKGRNPR DKLLVFSDAM DVGSIEETYH HFTGRVRLSF 

       370        380        390        400        410        420 
GWGTNLTNDF VGCAPDGSFN LDPISLVCKV SSVDGHPAVK LSDNPEKATG LPSEIERYLR 

       430 
VFGDVGRVRK PVLV 

« Hide

References

[1]"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110."
Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.
DNA Res. 9:189-197(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000040 Genomic DNA. Translation: BAC47592.1.
RefSeqNP_768967.1. NC_004463.1.

3D structure databases

ProteinModelPortalQ89SS3.
SMRQ89SS3. Positions 1-424.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224911.bll2327.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAC47592; BAC47592; BAC47592.
GeneID1050912.
KEGGbja:bll2327.
PATRIC21187996. VBIBraJap65052_2258.

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284929.
KOK00763.
OrthoDBEOG6X10XB.
PhylomeDBQ89SS3.

Enzyme and pathway databases

BioCycBJAP224911:GJEJ-2349-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERPTHR11098:SF1. PTHR11098:SF1. 1 hit.
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_BRADU
AccessionPrimary (citable) accession number: Q89SS3
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: June 1, 2003
Last modified: July 9, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways