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Q89SS3

- PNCB_BRADU

UniProt

Q89SS3 - PNCB_BRADU

Protein

Nicotinate phosphoribosyltransferase

Gene

pncB

Organism
Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.UniRule annotation

    Catalytic activityi

    Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. ligase activity Source: UniProtKB-KW
    2. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro
    3. nicotinate phosphoribosyltransferase activity Source: InterPro

    GO - Biological processi

    1. NAD biosynthetic process Source: UniProtKB-UniPathway
    2. nicotinate nucleotide biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Ligase, Transferase

    Keywords - Biological processi

    Pyridine nucleotide biosynthesis

    Enzyme and pathway databases

    BioCyciBJAP224911:GJEJ-2349-MONOMER.
    UniPathwayiUPA00253; UER00457.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Nicotinate phosphoribosyltransferaseUniRule annotation (EC:6.3.4.21UniRule annotation)
    Short name:
    NAPRTaseUniRule annotation
    Gene namesi
    Name:pncBUniRule annotation
    Ordered Locus Names:bll2327
    OrganismiBradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
    Taxonomic identifieri224911 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
    ProteomesiUP000002526: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 434434Nicotinate phosphoribosyltransferasePRO_1000146832Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi224911.bll2327.

    Structurei

    3D structure databases

    ProteinModelPortaliQ89SS3.
    SMRiQ89SS3. Positions 1-424.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the NAPRTase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1488.
    HOGENOMiHOG000284929.
    KOiK00763.
    OrthoDBiEOG6X10XB.
    PhylomeDBiQ89SS3.

    Family and domain databases

    HAMAPiMF_00570. NAPRTase.
    InterProiIPR006406. Nic_PRibTrfase.
    IPR007229. Nic_PRibTrfase-Fam.
    IPR002638. Quinolinate_PRibosylTrfase_C.
    [Graphical view]
    PANTHERiPTHR11098. PTHR11098. 1 hit.
    PfamiPF04095. NAPRTase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000484. NAPRT. 1 hit.
    SUPFAMiSSF51690. SSF51690. 1 hit.
    TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q89SS3-1 [UniParc]FASTAAdd to Basket

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    MTVTDIASRT YNHSWRLDPI IRSLLDTDFY KLLMLQMIRE DYSNQQVTFS    50
    VINRSRHVRL AEIIDEGELR AQLDHARTIR FTKKELIWLA GNTFYGKTHM 100
    FSADFIRWLA EFRLPEYELR KVEGQYELHF HGPWTHTTMW EIPALAILNE 150
    LRSRAAIKGR GRFELDVLYA RAKAKLWTKV ERLRKLENLR LSDFGTRRRH 200
    GFLWQRWCVE AVKEGLGPSF IGTSNVLLAM DNDLEAIGTN AHELPMVAAG 250
    LAKDDEELRW APYRILDQWR QTYGGNLLIA LPDAFGTKAF LRDAPEWVAD 300
    WTGFRPDSAP PIQAGEEIIA WWEKKGRNPR DKLLVFSDAM DVGSIEETYH 350
    HFTGRVRLSF GWGTNLTNDF VGCAPDGSFN LDPISLVCKV SSVDGHPAVK 400
    LSDNPEKATG LPSEIERYLR VFGDVGRVRK PVLV 434
    Length:434
    Mass (Da):49,902
    Last modified:June 1, 2003 - v1
    Checksum:i8EC682BBC4396356
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000040 Genomic DNA. Translation: BAC47592.1.
    RefSeqiNP_768967.1. NC_004463.1.

    Genome annotation databases

    EnsemblBacteriaiBAC47592; BAC47592; BAC47592.
    GeneIDi1050912.
    KEGGibja:bll2327.
    PATRICi21187996. VBIBraJap65052_2258.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000040 Genomic DNA. Translation: BAC47592.1 .
    RefSeqi NP_768967.1. NC_004463.1.

    3D structure databases

    ProteinModelPortali Q89SS3.
    SMRi Q89SS3. Positions 1-424.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 224911.bll2327.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAC47592 ; BAC47592 ; BAC47592 .
    GeneIDi 1050912.
    KEGGi bja:bll2327.
    PATRICi 21187996. VBIBraJap65052_2258.

    Phylogenomic databases

    eggNOGi COG1488.
    HOGENOMi HOG000284929.
    KOi K00763.
    OrthoDBi EOG6X10XB.
    PhylomeDBi Q89SS3.

    Enzyme and pathway databases

    UniPathwayi UPA00253 ; UER00457 .
    BioCyci BJAP224911:GJEJ-2349-MONOMER.

    Family and domain databases

    HAMAPi MF_00570. NAPRTase.
    InterProi IPR006406. Nic_PRibTrfase.
    IPR007229. Nic_PRibTrfase-Fam.
    IPR002638. Quinolinate_PRibosylTrfase_C.
    [Graphical view ]
    PANTHERi PTHR11098. PTHR11098. 1 hit.
    Pfami PF04095. NAPRTase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000484. NAPRT. 1 hit.
    SUPFAMi SSF51690. SSF51690. 1 hit.
    TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110.

    Entry informationi

    Entry nameiPNCB_BRADU
    AccessioniPrimary (citable) accession number: Q89SS3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 28, 2009
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 77 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3