Q89SS3 (PNCB_BRAJA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Nicotinate phosphoribosyltransferase
Short name=NAPRTase
EC=2.4.2.11

Gene names

Name:	pncB
Ordered Locus Names:	bll2327

Organism

Bradyrhizobium japonicum (strain USDA 110) [Reference proteome] [HAMAP]

Taxonomic identifier

224911 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium › Bradyrhizobium japonicum

Protein attributes

Sequence length	434 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Beta-nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP-Rule MF_00570
Pathway	Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the NAPRTase family.

Ontologies

Keywords
Biological process	Pyridine nucleotide biosynthesis
Cellular component	Cytoplasm
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	NAD biosynthetic process Inferred from electronic annotation. Source: HAMAP nicotinate nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	nicotinate phosphoribosyltransferase activity Inferred from electronic annotation. Source: HAMAP nicotinate-nucleotide diphosphorylase (carboxylating) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 434	434	Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570		PRO_1000146832

Sequences

	Sequence		Length	Mass (Da)
	Q89SS3 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 8EC682BBC4396356	FASTA	434	49,902
	10 20 30 40 50 60 MTVTDIASRT YNHSWRLDPI IRSLLDTDFY KLLMLQMIRE DYSNQQVTFS VINRSRHVRL 70 80 90 100 110 120 AEIIDEGELR AQLDHARTIR FTKKELIWLA GNTFYGKTHM FSADFIRWLA EFRLPEYELR 130 140 150 160 170 180 KVEGQYELHF HGPWTHTTMW EIPALAILNE LRSRAAIKGR GRFELDVLYA RAKAKLWTKV 190 200 210 220 230 240 ERLRKLENLR LSDFGTRRRH GFLWQRWCVE AVKEGLGPSF IGTSNVLLAM DNDLEAIGTN 250 260 270 280 290 300 AHELPMVAAG LAKDDEELRW APYRILDQWR QTYGGNLLIA LPDAFGTKAF LRDAPEWVAD 310 320 330 340 350 360 WTGFRPDSAP PIQAGEEIIA WWEKKGRNPR DKLLVFSDAM DVGSIEETYH HFTGRVRLSF 370 380 390 400 410 420 GWGTNLTNDF VGCAPDGSFN LDPISLVCKV SSVDGHPAVK LSDNPEKATG LPSEIERYLR 430 VFGDVGRVRK PVLV

References

[1]

"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110." Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S. DNA Res. 9:189-197(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: USDA 110.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000040 Genomic DNA. Translation: BAC47592.1.
RefSeq	NP_768967.1. NC_004463.1.
3D structure databases
HSSP	HSSP built from PDB template 1YBE based on UniProtKB Q8UIS9.
ProteinModelPortal	Q89SS3.
SMR	Q89SS3. Positions 1-424.
ModBase	Search...
Protein-protein interaction databases
STRING	224911.bll2327.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAC47592; BAC47592; BAC47592.
GeneID	1050912.
KEGG	bja:bll2327.
PATRIC	21187996. VBIBraJap65052_2258.
Phylogenomic databases
eggNOG	COG1488.
HOGENOM	HOG000284929.
KO	K00763.
OMA	SFGWGTN.
ProtClustDB	PRK05321.
Enzyme and pathway databases
BioCyc	BJAP224911:GJEJ-2349-MONOMER.
UniPathway	UPA00253; UER00457.
Family and domain databases
HAMAP	MF_00570. NAPRTase.
InterPro	IPR006406. Nic_PRibTrfase. IPR015977. Nic_PRibTrfase-like. IPR007229. Nic_PRibTrfase-rel. IPR002638. Quinolinate_PRibosylTrfase_C. [Graphical view]
PANTHER	PTHR11098:SF1. PTHR11098:SF1. 1 hit.
Pfam	PF04095. NAPRTase. 1 hit. [Graphical view]
PIRSF	PIRSF000484. NAPRT. 1 hit.
SUPFAM	SSF51690. Q_phspho_trans. 1 hit.
TIGRFAMs	TIGR01514. NAPRTase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PNCB_BRAJA

Accession

Primary (citable) accession number: Q89SS3

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	June 1, 2003
Last modified:	May 1, 2013
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program