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Reviewed, UniProtKB/Swiss-Prot Q89SC2 (HEM6_BRAJA)

Last modified June 16, 2009. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Coproporphyrinogen-III oxidase, aerobic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase
    EC=1.3.3.3
Gene names
Name: hemF
Ordered Locus Names: bll2481
OrganismBradyrhizobium japonicum [Complete proteome] [HAMAP]
Taxonomic identifier375 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

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Protein attributes

Sequence length316 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

Coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O. HAMAP MF_00333

Pathway

Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1. HAMAP MF_00333

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the aerobic coproporphyrinogen-III oxidase family.

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Ontologies

Keywords
   Biological processPorphyrin biosynthesis
   Cellular componentCytoplasm
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

porphyrin biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioncoproporphyrinogen oxidase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 316316Coproporphyrinogen-III oxidase, aerobic
PRO_0000109886

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Sequences

Sequence LengthMass (Da)Tools
Q89SC2-1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 8698744018E989CF

FASTA31635,498
        10         20         30         40         50         60 
MVGTAQGRLC PPYGRSVREL NMDVSTIEDR KTRARAWFEA LRDDICASFE RLEDDAPQGL 

        70         80         90        100        110        120 
YPGEAGRFTR TPWQRTDHSG AAGGGGVMSM MSGRLFEKVG VHCSTVHGEF APEFRAQIPG 

       130        140        150        160        170        180 
AADDPRFWAS GISLIAHLRN PHVPAVHMNT RFVVTTKAWF GGGADLTPVL DRRRTQDDAD 

       190        200        210        220        230        240 
SIAFHAAMKE ACVQPNGVAD YDKYKKWCDE YFYLPHRKEA RGIGGIFYDW HDSGDWDADL 

       250        260        270        280        290        300 
AFTQDVGRAF LKIYPDIVRR NFASAWTAAD REEQLIRRGR YVEFNLLYDR GTIFGLKTGG 

       310 
NVDSILSSLP PEVKWP

« Hide

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References

[1]"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110."
Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.
DNA Res. 9:189-197(2002) [PubMed: 12597275] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: USDA 110.

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Cross-references

Sequence databases

BA000040 Genomic DNA. Translation: BAC47746.1.
RefSeqNP_769121.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID1050400.
GenomeReviewsGene locus bll2481 in contig BA000040_GR.
KEGGbja:bll2481.
NMPDRfig|224911.1.peg.2481.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ89SC2.
OMAQ89SC2. VKAYLLD.

Enzyme and pathway databases

BioCycBJAP224911:BLL2481-MON.
BRENDA1.3.3.3. 280.

Family and domain databases

HAMAPMF_00333.
[Tree]
InterProIPR001260. Coprogen_oxidas.
IPR018375. Coproporphyrinogen-3_ox_CS.
[Graphical view]
Gene3DG3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHERPTHR10755. Coprogen_oxidas. 1 hit.
PfamPF01218. Coprogen_oxidas. 1 hit.
[Graphical view]
PIRSFPIRSF000166. Coproporphyri_ox. 1 hit.
PRINTSPR00073. COPRGNOXDASE.
PROSITEPS01021. COPROGEN_OXIDASE. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameHEM6_BRAJA
AccessionPrimary (citable) accession number: Q89SC2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: June 1, 2003
Last modified: June 16, 2009
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents