Q89RY1 (AROC_BRAJA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Chorismate synthase
EC=4.2.3.5

Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase

Gene names

Name:	aroC
Ordered Locus Names:	blr2631

Organism

Bradyrhizobium japonicum

Taxonomic identifier

375 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bradyrhizobiaceae › Bradyrhizobium

Protein attributes

Sequence length	362 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300
Cofactor	Reduced flavin By similarity. HAMAP MF_00300
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300
Subunit structure	Homotetramer By similarity. HAMAP MF_00300
Sequence similarities	Belongs to the chorismate synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Molecular function	Lyase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	chorismate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 362	362	Chorismate synthase HAMAP MF_00300		PRO_0000140560

Sequences

	Sequence		Length	Mass (Da)
	Q89RY1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 4F46B06A06D0ED0C	FASTA	362	38,947
	10 20 30 40 50 60 MSFNTFGHMF RVTTFGESHG VAIGCVVDGC PPMIPLTEAD IQGDLDRRRP GQSRFTTQRQ 70 80 90 100 110 120 EPDQVKILSG VMAHPETGVQ VTTGTPIGLL IENTDQRSKD YSEIKDKFRP GHADFTYEAK 130 140 150 160 170 180 YGLRDYRGGG RSSARETATR VAAGAIARKV LPDVKVRGAL VQMGPHKIDR EKWDWDEVAR 190 200 210 220 230 240 NPFFCPDKDK AAFFETYLDG IRKSGSSIGA VLEIVAEGVP AGLGAPIYAK LDSDLAGAMM 250 260 270 280 290 300 TINAVKGVEI GAGFGAAELT GEENADEMRT GNDGTRFLSN HAGGVLGGIS TGQPVVVRFA 310 320 330 340 350 360 VKPTSSILQP RLTVDRQGAD TEIMTKGRHD PCVGIRAVPV GEAMMACVLA DHFIRDRGQV GR

References

[1]

"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110." Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S. DNA Res. 9:189-197(2002) [PubMed: 12597275] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: USDA 110.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000040 Genomic DNA. Translation: BAC47896.1.
RefSeq	NP_769271.1. NC_004463.1.
3D structure databases
ProteinModelPortal	Q89RY1.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1048968.
GenomeReviews	Gene locus blr2631 in contig BA000040_GR.
KEGG	bja:blr2631.
NMPDR	fig|224911.1.peg.2631.
PATRIC	21188692. VBIBraJap65052_2605.
Phylogenomic databases
HOGENOM	HBG292336.
OMA	SRFTTQR.
PhylomeDB	Q89RY1.
ProtClustDB	PRK05382.
Enzyme and pathway databases
BioCyc	BJAP224911:BLR2631-MONOMER.
Family and domain databases
HAMAP	MF_00300. Chorismate_synth. [Tree]
InterPro	IPR000453. Chorismate_synth. IPR020541. Chorismate_synthase_CS. [Graphical view]
KO	K01736.
PANTHER	PTHR21085. Chorismate_synth. 1 hit.
Pfam	PF01264. Chorismate_synt. 1 hit. [Graphical view]
PIRSF	PIRSF001456. Chorismate_synth. 1 hit.
SUPFAM	SSF103263. Chorismate_synth. 1 hit.
TIGRFAMs	TIGR00033. AroC. 1 hit.
PROSITE	PS00787. CHORISMATE_SYNTHASE_1. 1 hit. PS00788. CHORISMATE_SYNTHASE_2. 1 hit. PS00789. CHORISMATE_SYNTHASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

AROC_BRAJA

Accession

Primary (citable) accession number: Q89RY1

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 7, 2005
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program