ID   Q89RT2_BRADU            Unreviewed;       300 AA.
AC   Q89RT2;
DT   01-JUN-2003, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2003, sequence version 1.
DT   27-MAR-2024, entry version 120.
DE   SubName: Full=Bll2680 protein {ECO:0000313|EMBL:BAC47945.1};
GN   OrderedLocusNames=bll2680 {ECO:0000313|EMBL:BAC47945.1};
OS   Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 /
OS   NBRC 14792 / USDA 110).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Nitrobacteraceae; Bradyrhizobium.
OX   NCBI_TaxID=224911 {ECO:0000313|EMBL:BAC47945.1, ECO:0000313|Proteomes:UP000002526};
RN   [1] {ECO:0000313|Proteomes:UP000002526}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110
RC   {ECO:0000313|Proteomes:UP000002526};
RX   PubMed=12597275; DOI=10.1093/dnares/9.6.189;
RA   Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S.,
RA   Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M.,
RA   Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
RT   "Complete genomic sequence of nitrogen-fixing symbiotic bacterium
RT   Bradyrhizobium japonicum USDA110.";
RL   DNA Res. 9:189-197(2002).
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DR   EMBL; BA000040; BAC47945.1; -; Genomic_DNA.
DR   RefSeq; NP_769320.1; NC_004463.1.
DR   RefSeq; WP_011085465.1; NZ_CP011360.1.
DR   AlphaFoldDB; Q89RT2; -.
DR   STRING; 224911.AAV28_10405; -.
DR   EnsemblBacteria; BAC47945; BAC47945; BAC47945.
DR   GeneID; 64022434; -.
DR   KEGG; bja:bll2680; -.
DR   PATRIC; fig|224911.44.peg.2287; -.
DR   eggNOG; COG2084; Bacteria.
DR   HOGENOM; CLU_035117_0_6_5; -.
DR   InParanoid; Q89RT2; -.
DR   OrthoDB; 9812907at2; -.
DR   PhylomeDB; Q89RT2; -.
DR   Proteomes; UP000002526; Chromosome.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IBA:GO_Central.
DR   GO; GO:0016054; P:organic acid catabolic process; IEA:UniProt.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR006115; 6PGDH_NADP-bd.
DR   InterPro; IPR029154; HIBADH-like_NADP-bd.
DR   InterPro; IPR015815; HIBADH-related.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR22981:SF7; 3-HYDROXYISOBUTYRATE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR22981; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED; 1.
DR   Pfam; PF14833; NAD_binding_11; 1.
DR   Pfam; PF03446; NAD_binding_2; 1.
DR   PIRSF; PIRSF000103; HIBADH; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002526}.
FT   DOMAIN          7..166
FT                   /note="6-phosphogluconate dehydrogenase NADP-binding"
FT                   /evidence="ECO:0000259|Pfam:PF03446"
FT   DOMAIN          173..288
FT                   /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT                   /evidence="ECO:0000259|Pfam:PF14833"
FT   ACT_SITE        175
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000103-1"
SQ   SEQUENCE   300 AA;  30966 MW;  6A962F24DFC7106E CRC64;
     MTDASRNVAF IGIGKMGLPM SVLVAKAGYA VTAFDRSAAR TNEARAQGIS IAASPDDAVS
     GKEAVITSLP DDTALRGALL GPAGVIAAMA PGAVLIETST VSVEASTEVA ASAQARGVLY
     LRAPVSGNAS IVHTGALTCF VSGPKDAFDN AKPLFAAFTR ARTYLGPAEE ARYAKLAVNL
     MIAVSAAMMA ESLALARKGG IAWQDILKVL DDSAVASPMV KYKTAPLRTR DFESTFSCKQ
     MAKDLDLILG AGHAVGVPLQ LAAQVRETYG SLVAQGDGEA DFIATVKHLE RLSGLGEPKL
//