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Protein

60 kDa chaperonin 4

Gene

groL4

Organism
Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperonin 4
Alternative name(s):
GroEL protein 4
Protein Cpn60 4
Gene namesi
Name:groL4
Synonyms:groEL
Ordered Locus Names:blr3683
OrganismiBradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Taxonomic identifieri224911 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
Proteomesi
  • UP000002526 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000632971 – 54360 kDa chaperonin 4Add BLAST543

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi224911.blr3683.

Structurei

3D structure databases

ProteinModelPortaliQ89P00.
SMRiQ89P00.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.Curated

Phylogenomic databases

eggNOGiENOG4108MFQ. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
InParanoidiQ89P00.
KOiK04077.
OMAiGYLSHHM.
OrthoDBiPOG091H1MHT.
PhylomeDBiQ89P00.

Family and domain databases

Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF52029. SSF52029. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

Q89P00-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPKVLLHDIE ARRALARGVQ KLAAAIESTL GPKGMNAMVD RPIGTPIVSR
60 70 80 90 100
DGVTIASEIE LPDRFENMGA QVVREVSMQT NEVAGDGTTT AMVLANGLIQ
110 120 130 140 150
GGVAALERGA KAVDLCKGID RAVEVVVESL KSAAIPVSDR RTLQAVATIA
160 170 180 190 200
STDSHLGDLI AEAVERVGKD GIISSDYGLT TSTTLEVVEG MSFDRGYISH
210 220 230 240 250
HMVTDVEKME VVLEQPYILL TDLKIKAPGE LAAVRARVAE TGKPLVIVAE
260 270 280 290 300
EIAPEVVVTL LGEGNRGKVL VVNPPDYGHW RKAMMDDLAI ITGGRVIARE
310 320 330 340 350
LGGMLEEASL ADLGTARQVR ASARETVIIR GGGDDAAIAA RRQQVAKQHD
360 370 380 390 400
LAPPNIEQDK LKERLAKLSG GTAVIFAGGV TPVEQKRTIQ LIDDALSAAR
410 420 430 440 450
AAAEEGIVPG GGTALAQCAP VVVRALGNIN GDLGEGIKLV RETLSRPAAF
460 470 480 490 500
IARNAGHDAA KVVAELQSSR AGVGFDAANG VFIDMVSAGI VDPVRVTYTA
510 520 530 540
LRNAASVATL VLTTNTLVAD VPEYVDPTQG PALGGGAEKL GRA
Length:543
Mass (Da):56,659
Last modified:June 1, 2003 - v1
Checksum:i555F36077A6C5574
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000040 Genomic DNA. Translation: BAC48948.1.
RefSeqiNP_770323.1. NC_004463.1.
WP_011086464.1. NZ_CP011360.1.

Genome annotation databases

EnsemblBacteriaiBAC48948; BAC48948; BAC48948.
GeneIDi1051467.
KEGGibja:blr3683.
PATRICifig|224911.44.peg.3347.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000040 Genomic DNA. Translation: BAC48948.1.
RefSeqiNP_770323.1. NC_004463.1.
WP_011086464.1. NZ_CP011360.1.

3D structure databases

ProteinModelPortaliQ89P00.
SMRiQ89P00.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224911.blr3683.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC48948; BAC48948; BAC48948.
GeneIDi1051467.
KEGGibja:blr3683.
PATRICifig|224911.44.peg.3347.

Phylogenomic databases

eggNOGiENOG4108MFQ. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
InParanoidiQ89P00.
KOiK04077.
OMAiGYLSHHM.
OrthoDBiPOG091H1MHT.
PhylomeDBiQ89P00.

Family and domain databases

Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF52029. SSF52029. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCH604_BRADU
AccessioniPrimary (citable) accession number: Q89P00
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: June 1, 2003
Last modified: June 7, 2017
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.