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Protein

Glutaminase 1

Gene

glsA1

Organism
Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei75SubstrateBy similarity1
Binding sitei124SubstrateBy similarity1
Binding sitei168SubstrateBy similarity1
Binding sitei175SubstrateBy similarity1
Binding sitei199SubstrateBy similarity1
Binding sitei251SubstrateBy similarity1
Binding sitei269Substrate; via amide nitrogenBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi480 – 595cNMPAdd BLAST116

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciBDIA224911:G1G3J-3960-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase 1 (EC:3.5.1.2)
Gene namesi
Name:glsA1
Ordered Locus Names:bll3935
OrganismiBradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Taxonomic identifieri224911 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
Proteomesi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001105971 – 613Glutaminase 1Add BLAST613

Proteomic databases

PRIDEiQ89NA7

Interactioni

Subunit structurei

Homotetramer.By similarity

Protein-protein interaction databases

STRINGi224911.bll3935

Structurei

3D structure databases

ProteinModelPortaliQ89NA7
SMRiQ89NA7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini345 – 457STASAdd BLAST113

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni33 – 315GlutaminaseAdd BLAST283

Sequence similaritiesi

Belongs to the glutaminase family.Curated

Phylogenomic databases

eggNOGiENOG4105CSV Bacteria
COG2066 LUCA
HOGENOMiHOG000216890
InParanoidiQ89NA7
KOiK01425
OMAiERPRNPM
OrthoDBiPOG091H02PU
PhylomeDBiQ89NA7

Family and domain databases

CDDicd00038 CAP_ED, 1 hit
Gene3Di2.60.120.10, 1 hit
3.30.750.24, 1 hit
HAMAPiMF_00313 Glutaminase, 1 hit
InterProiView protein in InterPro
IPR012338 Beta-lactam/transpept-like
IPR018490 cNMP-bd-like
IPR000595 cNMP-bd_dom
IPR015868 Glutaminase
IPR014710 RmlC-like_jellyroll
IPR002645 STAS_dom
IPR036513 STAS_dom_sf
PANTHERiPTHR12544 PTHR12544, 1 hit
PfamiView protein in Pfam
PF00027 cNMP_binding, 1 hit
PF04960 Glutaminase, 1 hit
SMARTiView protein in SMART
SM00100 cNMP, 1 hit
SUPFAMiSSF51206 SSF51206, 1 hit
SSF52091 SSF52091, 1 hit
SSF56601 SSF56601, 1 hit
TIGRFAMsiTIGR03814 Gln_ase, 1 hit
PROSITEiView protein in PROSITE
PS50042 CNMP_BINDING_3, 1 hit
PS50801 STAS, 1 hit

Sequencei

Sequence statusi: Complete.

Q89NA7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPPPASAWT RSKPPLLRFL DTCLNEFSAE TSGAVADYIP ELGNADPAYF
60 70 80 90 100
GISLATLDGH VYEVGDSRVP FTIQSMSKPF VFALALDLLG AGRVESAIGV
110 120 130 140 150
EPSGDPFNSI RLNSDNHPFN PMVNAGAIAC TGLIYDSKGA EAFEQIRLAL
160 170 180 190 200
SRFAGRDLAV DEAVYSSESQ TGDRNRAIGY LLKTNAVISD NVAAVLDVYF
210 220 230 240 250
RQCAVLVTAR DIAVMAATLA NRGINPVTGE QVMSAYAISR TLSVMTSSGM
260 270 280 290 300
YDYAGEWIYR IGIPAKSGVG GGILAALPAR LGLGSYSPKL DKHGNSVRGI
310 320 330 340 350
KVCEALSSHY DLHMLNRSDD ARNAVIADYD IGKSPSRRVR RAQEREILAA
360 370 380 390 400
HEQEVRIIEL VGTLSLSAVD YVSRRLAGRP RPQFVIFDLH RVTSTTRAGA
410 420 430 440 450
RLVAEAFEEL AALNVTVVLS GVRRASKEWN TLREWTAELK NVRDFYLLDT
460 470 480 490 500
AIEWAEDQIV YRYGGSIDFH ETTELAEQPL LEGLSADELA ELGAICTIRT
510 520 530 540 550
YQSGAKILTT GDPADALFFL RSGAVHVTLP DGVRLATLTA GMAFGEMALL
560 570 580 590 600
EQTRSADVFA DMAATAFEAP LKDFERFREQ HPRASERIMR NLAQLLADRL
610
IVANAKVDIL TST
Length:613
Mass (Da):66,635
Last modified:June 1, 2003 - v1
Checksum:i2F7F6A35D48DA118
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000040 Genomic DNA Translation: BAC49200.1
RefSeqiNP_770575.1, NC_004463.1
WP_011086712.1, NZ_CP011360.1

Genome annotation databases

EnsemblBacteriaiBAC49200; BAC49200; BAC49200
GeneIDi1053915
KEGGibja:bll3935
PATRICifig|224911.44.peg.3628

Entry informationi

Entry nameiGLSA1_BRADU
AccessioniPrimary (citable) accession number: Q89NA7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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