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Protein

Guanylate kinase

Gene

gmk

Organism
Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi22 – 29ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBDIA224911:G1G3J-4113-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:blr4088
OrganismiBradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Taxonomic identifieri224911 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
Proteomesi
  • UP000002526 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001705071 – 219Guanylate kinaseAdd BLAST219

Interactioni

Protein-protein interaction databases

STRINGi224911.blr4088

Structurei

3D structure databases

ProteinModelPortaliQ89MV4
SMRiQ89MV4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini15 – 194Guanylate kinase-likeUniRule annotationAdd BLAST180

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UHA Bacteria
COG0194 LUCA
HOGENOMiHOG000037638
InParanoidiQ89MV4
KOiK00942
OMAiAGNYYGT
OrthoDBiPOG091H01Q4
PhylomeDBiQ89MV4

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q89MV4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTGGHGTDG VERRGLMFVL SSPSGAGKTT LSRLLIERMP GLRMSVSATT
60 70 80 90 100
RPMRPGEVDG RDYLFVDKPR FEAMVRDDEL LEWATVFDNR YGTPRAPVEA
110 120 130 140 150
ALSAGQDVLF DIDWQGTQQL REKARADVVS VFILPPSAGD LEKRLHSRAQ
160 170 180 190 200
DSDEVIRKRM SRASHEMSHW AEYDYIVINH DVDEAFAEVQ SILKAERLKR
210
ERRIGLVGFV RGLQGQLQG
Length:219
Mass (Da):24,628
Last modified:June 20, 2003 - v1
Checksum:i330AFCAADBB04C02
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000040 Genomic DNA Translation: BAC49353.1
RefSeqiNP_770728.1, NC_004463.1
WP_011086862.1, NZ_CP011360.1

Genome annotation databases

EnsemblBacteriaiBAC49353; BAC49353; BAC49353
GeneIDi1048138
KEGGibja:blr4088
PATRICifig|224911.5.peg.4102

Similar proteinsi

Entry informationi

Entry nameiKGUA_BRADU
AccessioniPrimary (citable) accession number: Q89MV4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 20, 2003
Last sequence update: June 20, 2003
Last modified: March 28, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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